MicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  American Journal of Physiology - Lung cellular and Molecular Physiology

• Publication date

  2014-10-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/ajplung.00127.2014PMID 25172912PMCID PMC4200385
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway.

  2014cited by this paper
• miR-17-5p Downregulation Contributes to Paclitaxel Resistance of Lung Cancer Cells through Altering Beclin1 Expression

  2014cited by this paper
• Integrated analyses identify the involvement of microRNA-26a in epithelial–mesenchymal transition during idiopathic pulmonary fibrosis

  2014cited by this paper
• IPF Fibroblasts Are Desensitized to Type I Collagen Matrix-Induced Cell Death by Suppressing Low Autophagy via Aberrant Akt/mTOR Kinases

  2014cited by this paper
• The antifibrotic effects and mechanisms of microRNA-26a action in idiopathic pulmonary fibrosis.

  2014cited by this paper
• Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity.

  2013cited by this paper
• PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells

  2013cited by this paper
• Epigenetic regulation of miR-17~92 contributes to the pathogenesis of pulmonary fibrosis.

  2013cited by this paper
• Circulating MicroRNAs in Relation to EGFR Status and Survival of Lung Adenocarcinoma in Female Non-Smokers

  2013cited by this paper
• Foxo3a Expression Is a Prognostic Marker in Breast Cancer

  2013cited by this paper
• FoxO3a (Forkhead Box O3a) Deficiency Protects Idiopathic Pulmonary Fibrosis (IPF) Fibroblasts from Type I Polymerized Collagen Matrix-Induced Apoptosis via Caveolin-1 (cav-1) and Fas

  2013cited by this paper
• miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer.

  2013cited by this paper
• Deregulation of FoxO3a accelerates prostate cancer progression in TRAMP mice

  2013cited by this paper
• Serum miR-21 and miR-155 expression in idiopathic pulmonary fibrosis

  2013cited by this paper
• Antagonism between FOXO and MYC Regulates Cellular Powerhouse

  2013cited by this paper
• Gene silencing in vitro and in vivo using intronic microRNAs.

  2013cited by this paper
• Activity of the selective IκB kinase inhibitor BMS-345541 against T-cell acute lymphoblastic leukemia

  2012cited by this paper
• Forkhead Transcription Factor FOXO3a Protein Activates Nuclear Factor κB through B-cell lymphoma/leukemia 10 (BCL10) Protein and Promotes Tumor Cell Survival in Serum Deprivation*

  2012cited by this paper
• An Aqueous Extract of Fagonia cretica Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Breast Cancer Cells via FOXO3a and p53 Expression

  2012cited by this paper
• Noncoding RNAs in gene regulation

  2011cited by this paper
• FoxO3a Functions as a Key Integrator of Cellular Signals That Control Glioblastoma Stem‐like Cell Differentiation and Tumorigenicity

  2011cited by this paper
• Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis.

  2011cited by this paper
• Pathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrix.

  2011cited by this paper
• Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors

  2011cited by this paper
• Pancreatic Tumor Suppression by Benzyl Isothiocyanate Is Associated with Inhibition of PI3K/AKT/FOXO Pathway

  2011cited by this paper
• Constitutively Nuclear FOXO3a Localization Predicts Poor Survival and Promotes Akt Phosphorylation in Breast Cancer

  2010cited by this paper
• Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer.

  2010cited by this paper
• Unregulated miR-96 Induces Cell Proliferation in Human Breast Cancer by Downregulating Transcriptional Factor FOXO3a

  2010influential reference
• PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27Kip1

  2008cited by this paper
• Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

  2008influential reference
• Dynamic FoxO transcription factors

  2007cited by this paper
• Enhanced myofibroblastic differentiation and survival in Thy-1(-) lung fibroblasts.

  2007cited by this paper
• Gene silencing in vitro and in vivo using intronic microRNAs.

  2006cited by this paper
• PI3K/Akt/FOXO3a Pathway Contributes to Thrombopoietin-Induced Proliferation of Primary Megakaryocytes In Vitro and In Vivo Via Modulation of p27 Kip1 .

  2005cited by this paper
• NPM-ALK fusion kinase of anaplastic large-cell lymphoma regulates survival and proliferative signaling through modulation of FOXO3a.

  2004cited by this paper
• Focal Adhesion Kinase Is Upstream of Phosphatidylinositol 3-Kinase/Akt in Regulating Fibroblast Survival in Response to Contraction of Type I Collagen Matrices via a β1 Integrin Viability Signaling Pathway*

  2004cited by this paper
• FoxO3a Transcriptional Regulation of Bim Controls Apoptosis in Paclitaxel-treated Breast Cancer Cell Lines*

  2003cited by this paper
• Idiopathic pulmonary fibrosis: relationship between histopathologic features and mortality.

  2001cited by this paper
• Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway.

  2001cited by this paper
• Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.

  1999cited by this paper
• Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification.

  1998cited by this paper
• Idiopathic pulmonary fibrosis: predicting response to therapy and survival.

  1998cited by this paper
• CT findings during phase of accelerated deterioration in patients with idiopathic pulmonary fibrosis.

  1997cited by this paper
• The roles of the myofibroblast in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis.

  1991cited by this paper
• An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis.

  1989cited by this paper
• Intraluminal fibrosis in interstitial lung disorders.

  1986cited by this paper

• The dual missions of FoxO3a in inflammatory diseases: Regulation of antioxidant enzymes and involvement in programmed cell death.

  2025cites this paper
• Emerging roles of non-coding RNAs in fibroblast to myofibroblast transition and fibrotic diseases

  2024cites this paper
• Sirolimus-eluting airway stent reduces profibrotic Th17 cells and inhibits laryngotracheal stenosis

  2023cites this paper
• Systematic review of overlapping microRNA patterns in COVID-19 and idiopathic pulmonary fibrosis

  2023cites this paper
• Epigenetic hallmarks in pulmonary fibrosis: New advances and perspectives.

  2023cites this paper
• Emerging delivery approaches for targeted pulmonary fibrosis treatment.

  2023cites this paper
• FoxO3 and oxidative stress: a multifaceted role in cellular adaptation

  2023cites this paper
• Delivery of anti-microRNA-21 by lung-targeted liposomes for pulmonary fibrosis treatment

  2023cites this paper
• The mRNA expression of Forkhead box O3a (FOXO3a) as a longevity-associated gene in leucocytes of elderly women.

  2021cites this paper
• Zanubrutinib Attenuated Bleomycin-Induced Pulmonary Fibrosis by Inhibiting the TGF-β1 Signaling Pathway

  2021cites this paper
• Carbon black nanoparticles induce pulmonary fibrosis through NLRP3 inflammasome pathway modulated by miR-96 targeted FOXO3a.

  2020cites this paper
• More than a Genetic Code: Epigenetics of Lung Fibrosis

  2020cites this paper
• Autophagy-related MicroRNAs in chronic lung diseases and lung cancer.

  2020cites this paper
• RETRACTED ARTICLE: Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13

  2020cites this paper
• P27 Promotes TGF-β-Mediated Pulmonary Fibrosis via Interacting with MTORC2

  2019cites this paper
• Molecular determinants of mesenchymal cell activation in fibroproliferative diseases

  2019cites this paper
• Fibroblasts from patients with idiopathic pulmonary fibrosis are resistant to cisplatin-induced cell death via enhanced CK2-dependent XRCC1 activity

  2019cites this paper
• Aberrant MicroRNAomics in Pulmonary Complications: Implications in Lung Health and Diseases

  2019cites this paper
• Molecular pathogenesis involved in human idiopathic pulmonary fibrosis based on an integrated microRNA-mRNA interaction network

  2018cites this paper
• MicroRNAs in idiopathic pulmonary fibrosis, new research progress and their pathophysiological implication

  2018cites this paper
• FOXO1/3: Potential suppressors of fibrosis.

  2018cites this paper
• Critical role of FOXO3a in carcinogenesis

  2018cites this paper
• FoxM1-dependent RAD51 and BRCA2 signaling protects idiopathic pulmonary fibrosis fibroblasts from radiation-induced cell death

  2018cites this paper
• Association of rno‐miR‐183‐96‐182 cluster with diethyinitrosamine induced liver fibrosis in Wistar rats

  2018cites this paper
• Treprostinil inhibits proliferation and extracellular matrix deposition by fibroblasts through cAMP activation

  2018cites this paper
• The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis

  2018influential citation
• Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1

  2017cites this paper
• Transforming growth factor-beta and Forkhead box O transcription factors as cardiac fibroblast regulators.

  2017cites this paper
• The effects of collagen-rich extracellular matrix on the intracellular delivery of glycol chitosan nanoparticles in human lung fibroblasts

  2017cites this paper
• A systematic review of overlapping microRNA patterns in systemic sclerosis and idiopathic pulmonary fibrosis

  2017cites this paper
• miR-96-5p prevents hepatic stellate cell activation by inhibiting autophagy via ATG7

  2017cites this paper
• Aryl hydrocarbon receptor (AhR)-dependent regulation of pulmonary miRNA by chronic cigarette smoke exposure

  2017cites this paper
• Posttranscriptional regulation of FOXO expression: microRNAs and beyond

  2017cites this paper
• IPF and lung cancer: homologous but different endings, the progress in the correlation research

  2017cites this paper
• MicroRNAs in Idiopathic Pulmonary Fibrosis: Partners in Health and Disease

  2017cites this paper
• MicroRNAs in idiopathic pulmonary fibrosis: involvement in pathogenesis and potential use in diagnosis and therapeutics

  2016cites this paper
• Serum extracellular vesicular miR-21-5p is a predictor of the prognosis in idiopathic pulmonary fibrosis

  2016cites this paper
• MicroRNAs as regulators and mediators of forkhead box transcription factors function in human cancers

  2016cites this paper
• Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease.

  2016cites this paper
• An oncogenic role of miR-592 in tumorigenesis of human colorectal cancer by targeting Forkhead Box O3A (FoxO3A)

  2016cites this paper
• Na/K-ATPase signaling regulates collagen synthesis through microRNA-29b-3p in cardiac fibroblasts.

  2016cites this paper
• Na / K-ATPase signaling regulates collagen synthesis through microRNA-29 b-3 p in cardiac fibroblasts

  2016cites this paper
• Idiopathic pulmonary fibrosis fibroblasts become resistant to Fas ligand‐dependent apoptosis via the alteration of decoy receptor 3

  2016cites this paper
• Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients

  2015cites this paper
• MiR-592 represses FOXO3 expression and promotes the proliferation of prostate cancer cells.

  2015cites this paper
• MicroRNAs in lung diseases: Recent findings and their pathophysiological implications.

  2015cites this paper
• miR-124 regulates fetal pulmonary epithelial cell maturation.

  2015cites this paper
• MicroRNAs as potential targets for progressive pulmonary fibrosis

  2015cites this paper
• The code of non-coding RNAs in lung fibrosis

  2015influential citation
• The Role of Aging in Idiopathic Pulmonary Fibrosis

  2015cites this paper
• The case for epigenomics in idiopathic pulmonary fibrosis

  2015cites this paper