Stimulants as Specific Inducers of Dopamine-Independent σ Agonist Self-Administration in Rats

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Pharmacology and Experimental Therapeutics

• Publication date

  2013-10-01

• Fields of study

  Medicine, Chemistry, Psychology

• Identifiers
  DOI 10.1124/jpet.113.207522PMID 23908387PMCID PMC3781409
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Self-Administration of Cocaine Induces Dopamine-Independent Self-Administration of Sigma Agonists

  2013influential reference
• Cocaine Inhibits Dopamine D2 Receptor Signaling via Sigma-1-D2 Receptor Heteromers

  2013cited by this paper
• Dews Award Lecture Behavioral and Pharmacological Determinants of Pharmacological Plasticity

  2013cited by this paper
• Agents in Development for the Management of Cocaine Abuse

  2012cited by this paper
• Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement

  2012cited by this paper
• A Role for Sigma Receptors in Stimulant Self Administration and Addiction

  2011cited by this paper
• Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors

  2011cited by this paper
• Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and (cid:1) Receptors

  2011cited by this paper
• Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis.

  2011influential reference
• Lack of cocaine-like discriminative-stimulus effects of &sgr;-receptor agonists in rats

  2011cited by this paper
• Reinforcing Effects of σ-Receptor Agonists in Rats Trained to Self-Administer Cocaine

  2010cited by this paper
• Reinforcing Effects of (cid:1) -Receptor Agonists in Rats Trained to Self-Administer Cocaine

  2010cited by this paper
• Direct involvement of σ-1 receptors in the dopamine D1 receptor-mediated effects of cocaine

  2010cited by this paper
• The Hallucinogen N,N-Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator

  2009cited by this paper
• Assessment of Reinforcing Effects of Benztropine Analogs and Their Effects on Cocaine Self-Administration in Rats: Comparisons with Monoamine Uptake Inhibitors

  2009cited by this paper
• The pharmacology of sigma-1 receptors.

  2009cited by this paper
• Influence of conditioned reinforcement on the response-maintaining effects of quinpirole in rats

  2009cited by this paper
• Targeting sigma receptors: novel medication development for drug abuse and addiction

  2009cited by this paper
• Alterations in Fos-Related Antigen 2 and σ1 Receptor Gene and Protein Expression Are Associated with the Development of Cocaine-Induced Behavioral Sensitization: Time Course and Regional Distribution Studies

  2008cited by this paper
• Drug and Reinforcement History as Determinants of the Response-Maintaining Effects of Quinpirole in the Rat

  2007cited by this paper
• Protein Kinase A Activation Down-Regulates, Whereas Extracellular Signal-Regulated Kinase Activation Up-Regulates σ-1 Receptors in B-104 Cells: Implication for Neuroplasticity

  2007cited by this paper
• Differential Effects of σ1 Receptor Blockade on Self-Administration and Conditioned Reinstatement Motivated by Cocaine vs Natural Reward

  2007cited by this paper
• Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival.

  2007cited by this paper
• Interactions of Cocaine with Dopamine Uptake Inhibitors or Dopamine Releasers in Rats Discriminating Cocaine

  2006cited by this paper
• Medication development for addictive disorders: the state of the science.

  2005cited by this paper
• Repeated Cocaine Administration Induces Gene Expression Changes through the Dopamine D1 Receptors

  2005cited by this paper
• Cocaine Up-Regulates Fra-2 and σ-1 Receptor Gene and Protein Expression in Brain Regions Involved in Addiction and Reward

  2005cited by this paper
• Pharmacotherapy and other treatments for cocaine abuse and dependence

  2005cited by this paper
• Dopamine Agonist-Induced Yawning in Rats: A Dopamine D3 Receptor-Mediated Behavior

  2005cited by this paper
• Sigma1 receptor upregulation after chronic methamphetamine self-administration in rats: a study with yoked controls

  2004cited by this paper
• Sigma1 receptor agonist-mediated regulation of N-methyl-D-aspartate-stimulated [3H]dopamine release is dependent upon protein kinase C.

  2003cited by this paper
• ς1 Receptor Agonist-Mediated Regulation ofN-Methyl-d-aspartate-Stimulated [3H]Dopamine Release Is Dependent upon Protein Kinase C

  2003cited by this paper
• The sigma receptor as a ligand-regulated auxiliary potassium channel subunit.

  2002cited by this paper
• Involvement of the Sigma1 Receptor in Cocaine-induced Conditioned Place Preference: Possible Dependence on Dopamine Uptake Blockade

  2002cited by this paper
• Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice.

  2001cited by this paper
• Involvement of the σ1 receptor in the cocaine‐induced conditioned place preference

  2000cited by this paper
• Self-administration of remifentanil, an ultra-short acting opioid, under continuous and progressive-ratio schedules of reinforcement in rats

  2000cited by this paper
• Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference.

  2000cited by this paper
• Two novel sigma receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activity.

  1999cited by this paper
• Two novel σ receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activity

  1999cited by this paper
• Neuroadaptations in the dopaminergic system after active self-administration but not after passive administration of methamphetamine.

  1999cited by this paper
• Discriminative stimulus properties of the putative dopamine D3 receptor agonist, (+)-PD 128907: role of presynaptic dopamine D2 autoreceptors.

  1998cited by this paper
• Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism.

  1997cited by this paper
• Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

  1996cited by this paper
• Preclinical Evaluation of Pharmacotherapies for Treatment of Cocaine and Opioid Abuse Using Drug Self-Administration Procedures

  1996cited by this paper
• Comparison of binding parameters of σ1 and σ2 binding sites in rat and guinea pig brain membranes: novel subtype-selective trishomocubanes

  1996cited by this paper
• Comparison of binding parameters of sigma 1 and sigma 2 binding sites in rat and guinea pig brain membranes: novel subtype-selective trishomocubanes.

  1996cited by this paper
• Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens.

  1995cited by this paper
• Effects of buprenorphine and other opioid agonists and antagonists on alfentanil- and cocaine-reinforced responding in rhesus monkeys.

  1992cited by this paper
• Behavioral effects of selective dopaminergic compounds in rats discriminating cocaine injections.

  1991cited by this paper
• Antagonism of cocaine self‐administration by selective dopamine D1 and D2 antagonists

  1990cited by this paper
• Evidence for a model of activation of central sigma systems.

  1989cited by this paper
• Reinforcing effect of alfentanil is mediated by mu opioid receptors: apparent pA2 analysis.

  1989cited by this paper
• Comparison of the pharmacological characteristics of [3H]raclopride and [3H]SCH 23390 binding to dopamine receptors in vivo in mouse brain.

  1988cited by this paper
• Naloxone-inaccessible sigma receptor in rat central nervous system.

  1983cited by this paper
• Continuous intravenous naltrexone effects on morphine self-administration in rhesus monkeys.

  1978cited by this paper
• STATISTICAL METHODS

  1967cited by this paper
• Regulation of (cid:1) -1 Receptors and Endoplasmic Reticulum Chaperones in the Brain of Methamphetamine Self-Administering Rats

  year unknowncited by this paper

• Relational Databases for Behavior Science

  2025cites this paper
• Preclinical Profile of CM699 as a Medication Candidate for Stimulant Use Disorder.

  2025cites this paper
• A Sigma1 Receptor Agonist Alters Fluidity and Stability of Lipid Monolayers.

  2024cites this paper
• Therapeutic targeting of neuroinflammation in methamphetamine use disorder.

  2024cites this paper
• Ventilatory Effects of Fentanyl, Heroin, and d-Methamphetamine, Alone and in Mixtures in Male Rats Breathing Normal Air 

  2023cites this paper
• In vitro and in vivo pharmacology of kratom.

  2022cites this paper
• Therapeutic potentials of NOP and MOP receptor coactivation for the treatment of pain and opioid abuse

  2020cites this paper
• Structure-Activity Relationships for a series of bis(4-fluorophenyl)methyl)sulfinyl)alkyl alicyclic amines at the dopamine transporter: functionalizing the terminal nitrogen affects affinity, selectivity and metabolic stability.

  2019cites this paper
• Effects of NOP-Related Ligands in Nonhuman Primates.

  2019cites this paper
• Inhibition of naltrexone on relapse in methamphetamine self-administration and conditioned place preference in rats.

  2019cites this paper
• The sigma-1 receptor as a regulator of dopamine neurotransmission: A potential therapeutic target for methamphetamine addiction.

  2018cites this paper
• Selective Pharmacological Augmentation of Hippocampal Activity Produces a Sustained Antidepressant-Like Response without Abuse-Related or Psychotomimetic Effects

  2017cites this paper
• Methamphetamine Induces Dopamine Release in the Nucleus Accumbens Through a Sigma Receptor-Mediated Pathway

  2017cites this paper
• A Role for Sigma Receptors in Stimulant Self-Administration and Addiction.

  2017cites this paper
• σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration

  2017cites this paper
• Effects of environmental enrichment on self-administration of the short-acting opioid remifentanil in male rats

  2017cites this paper
• A role for sigma receptors in stimulant self-administration and addiction

  2016influential citation
• Potential Molecular Mechanisms on the Role of the Sigma-1 Receptor in the Action of Cocaine and Methamphetamine.

  2016cites this paper
• Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors.

  2016cites this paper
• Identification of Antagonists Selective for Sigma Receptor Subtypes that are Active In vivo.

  2016cites this paper
• Identification of the Sigma-2 Receptor: Distinct from the Progesterone Receptor Membrane Component 1 (PGRMC1)

  2016cites this paper
• Importance of Substrate-Coupled Proton Antiport by the Vesicular Monoamine Transporter in the Actions of Amphetamines in Drosophila Brain.

  2016cites this paper
• Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists

  2016influential citation
• Role for Reactive Oxygen Species in Methamphetamine Modulation of Dopamine Release in the Striatum

  2016cites this paper
• Blockade of Cocaine or Sigma Receptor Agonist Self-Administration by Subtype- Selective Sigma Receptor Antagonists

  2016influential citation
• Ketamine: Promising Path or False Prophecy in the Development of Novel Therapeutics for Mood Disorders?

  2015cites this paper
• Trace Amine-Associated Receptor Type 1 as A Target for The Development of Treatments for Stimulant Abuse

  2015cites this paper
• Differential Roles for Dopamine D1-Like and D2-Like Receptors in Mediating the Reinforcing Effects of Cocaine: Convergent Evidence from Pharmacological and Genetic Studies

  2015cites this paper
• Medications Discovery: Importance of Assessment of Drug Self Administration Dose-Effect Curves

  2015cites this paper
• Self-Administration of an Endogenous Cannabinoid 2-Arachidonoylglycerol in Experimentally Naïve Rats

  2015cites this paper
• Ketamine: Promising Path or False Prophecy in the Development of Novel Therapeutics for Mood Disorders?

  2015cites this paper
• Preclinical Efficacy of N-Substituted Benztropine Analogs as Antagonists of Methamphetamine Self-Administration in Rats

  2014cites this paper
• Role of the σRs for Development of Medications.

  2014cites this paper