Chronic fluoride toxicity decreases the number of nicotinic acetylcholine receptors in rat brain.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Neurotoxicology and Teratology

• Publication date

  2002-11-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/S0892-0362(02)00273-8PMID 12460657
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Changes in nicotinic acetylcholine receptor subunits expression in brain of patients with Down syndrome and Alzheimer's disease.

  2001cited by this paper
• Down syndrome: advances in molecular biology and the neurosciences.

  2001cited by this paper
• Reduced expression of neuronal nicotinic acetylcholine receptors during the early stages of damage by oxidative stress in PC12 cells

  2001cited by this paper
• Neuronal nicotinic receptors in the human brain.

  2000cited by this paper
• Influence of lipid peroxidation on the nicotinic acetylcholine receptors in PC12 cells.

  2000cited by this paper
• Decreased Protein Levels of Nicotinic Receptor Subunits in the Hippocampus and Temporal Cortex of Patients with Alzheimer’s Disease

  2000cited by this paper
• Nicotinic receptors in the brain: correlating physiology with function.

  1999cited by this paper
• Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain.

  1999cited by this paper
• The Role of Superoxide Dismutation in Malaria Parasites

  1999cited by this paper
• Lipid Peroxides in the Free Radical Pathophysiology of Brain Diseases

  1998cited by this paper
• Schizophrenia, sensory gating, and nicotinic receptors.

  1998cited by this paper
• Influence of chronic fluorosis on membrane lipids in rat brain.

  1998cited by this paper
• Nicotinic System Involvement in Alzheimer’s and Parkinson’s Diseases

  1997cited by this paper
• 3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat α7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner

  1997cited by this paper
• Nicotinic acetylcholine receptors in health and disease

  1997cited by this paper
• 3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat alpha7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner.

  1997cited by this paper
• Human neuronal nicotinic receptors.

  1997cited by this paper
• The great dilemma.

  1995cited by this paper
• Neurotoxicity of sodium fluoride in rats.

  1995cited by this paper
• [Effect of excessive fluoride intake on mental work capacity of children and a preliminary study of its mechanism].

  1994cited by this paper
• Recent studies on endemic fluorosis in China

  1994cited by this paper
• Human nicotinic receptors--their role in aging and dementia.

  1994cited by this paper
• Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

  1993cited by this paper
• [The effect of fluorine on the developing human brain].

  1992cited by this paper
• An experimental study of blood biochemical diagnostic indices for chronic fluorosis

  1991cited by this paper
• A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX.

  1990cited by this paper
• [Experimental study of behavior and cerebral morphology of rat pups generated by fluorotic female rat].

  1989cited by this paper
• Experimental study of behavior and cerebral morphology of rat pups generated by fluorotic female rat

  1989cited by this paper
• Stabilization of acetylcholine receptor secondary structure by cholesterol and negatively charged phospholipids in membranes.

  1987cited by this paper
• Correlation between acetylcholine receptor function and structural properties of membranes.

  1986cited by this paper
• Fluoride tissue distribution: short-term kinetics.

  1979cited by this paper
• Direct potentiometric determination of total ionic fluoride in biological fluids.

  1972cited by this paper

• Prenatal fluoride exposure and autistic behaviors in preschool-aged children: the Maternal-Infant Research on Environmental Chemicals (MIREC) cohort study

  2025cites this paper
• The Role of GSK3β Signaling Mediated Lysosomal Biosynthesis Dysregulation in Fluoride-Induced Neurological Impairment.

  2025cites this paper
• Maternal Urinary Fluoride and Child Neurobehavior at Age 36 Months

  2024cites this paper
• Molecular basis of fluoride toxicities: Beyond benefits and implications in human disorders

  2022cites this paper
• Study on Environmental Factors of Fluorine in Chagan Lake Catchment, Northeast China

  2021cites this paper
• Fluoride and human health: Systematic appraisal of sources, exposures, metabolism, and toxicity

  2020cites this paper
• Renal adaptive response to exposure to low doses of uranyl nitrate and sodium fluoride in mice.

  2020cites this paper
• LITERATURE SEARCH RESULTS FOR THE SYSTEMATIC REVIEW OF FLUORIDE EXPOSURE AND NEURODEVELOPMENTAL AND COGNITIVE HEALTH EFFECTS

  2020cites this paper
• Apoptotic and Degenerative Changes in the Enteric Nervous System Following Exposure to Fluoride During Pre- and Post-natal Periods

  2020cites this paper
• Transcriptome analysis reveals the mechanism of fluorine exposure on memory loss of common carp.

  2020cites this paper
• Principles of fluoride toxicity and the cellular response: a review

  2020cites this paper
• Inorganic fluoride and functions of brain

  2020cites this paper
• Effect of Andrographis paniculata and Phyllanthus amarus leaf extracts on selected biochemical indices in Drosophila melanogaster model of neurotoxicity

  2020cites this paper
• Integrated transcriptomic and proteomic analysis indicated that neurotoxicity of rats with chronic fluorosis may be in mechanism involved in the changed cholinergic pathway and oxidative stress.

  2020cites this paper
• Submission to NAS on the revised draft NTP Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects

  2019cites this paper
• Selective, Fast-Response, and Regenerable Metal-Organic Framework for Sampling Excess Fluoride Levels in Drinking Water.

  2019cites this paper
• Long-term exposure to fluoride as a factor promoting changes in the expression and activity of cyclooxygenases (COX1 and COX2) in various rat brain structures.

  2019cites this paper
• 52-76 sfs Epub061 Oto Anxiety Nov 6 1133.fm

  2019cites this paper
• EFFECT OF ACUTE AND CHRONIC FLUORIDE ADMINISTRATION ON BONE HISTOPATHOLOGY, BONE FLUORIDE ACCUMULATION, AND LOCOMOTOR ACTIVITY IN AN ANIMAL MODEL OF PALEOPATHOLOGICAL FLUOROSIS

  2019cites this paper
• 77-89 sfs Epub059 Arihan bone Oct 5 0634.fm

  2019cites this paper
• A mechanism underlying the neurotoxicity induced by sodium fluoride and its reversal by epigallocatechin gallate in the rat hippocampus: involvement of NrF2/Keap-1 signaling pathway

  2018cites this paper
• Association between water fluoride and the level of children's intelligence: a dose-response meta-analysis.

  2018cites this paper
• Effect of acetylcholinesterase inhibitors donepezil and rivastigmine on the activity and expression of cyclooxygenases in a model of the inflammatory action of fluoride on macrophages obtained from THP-1 monocytes.

  2018cites this paper
• Alterations in the memory of rat offspring exposed to low levels of fluoride during gestation and lactation: Involvement of the α7 nicotinic receptor and oxidative stress.

  2018cites this paper
• Effects of Fluoride Exposure on Motor Performance, Depression and Memory in Elderly Mice

  2018cites this paper
• Fluoride Induces Neuroinflammation and Alters Wnt Signaling Pathway in BV2 Microglial Cells

  2017cites this paper
• Fluoride: A review of pre-clinical and clinical studies.

  2017cites this paper
• Neuroprotective influence of taurine on fluoride-induced biochemical and behavioral deficits in rats.

  2017cites this paper
• Deficit in learning and memory of rats with chronic fluorosis correlates with the decreased expressions of M1 and M3 muscarinic acetylcholine receptors

  2015cites this paper
• Effects of fluoride on microtubule ultrastructure and expression of Tubα1a and Tubβ2a in mouse hippocampus.

  2015cites this paper
• Behavioral and general effects of subacute oral arsenic exposure in rats with and without fluoride

  2015cites this paper
• Distribution and Removal of Fluoride Ions in the Drinking Waters in the Algerian South (Ouargla as a Showcase)

  2015cites this paper
• Fluoride-Induced Neuron Apoptosis and Expressions of Inflammatory Factors by Activating Microglia in Rat Brain

  2015cites this paper
• ALTERATIONS OF APOPTOSIS AND EXPRESSIONS OF Bax AND Bcl-2 IN THE CEREBRAL CORTICES OF RATS WITH CHRONIC FLUOROSIS

  2014cites this paper
• Fluoride and Arsenic Exposure Impairs Learning and Memory and Decreases mGluR5 Expression in the Hippocampus and Cortex in Rats

  2014cites this paper
• EFFECTS OF FLUORIDE EXPOSURE ON THE GROWTH , METAMORPHOSIS , AND SKELETAL DEVELOPMENT OF RANA CHENSINESIS AND RANA NIGROMACULATA LARVAE

  2014cites this paper
• Fluoride exposure during development affects both cognition and emotion in mice.

  2014cites this paper
• The influence of chronic fluorosis on mitochondrial dynamics morphology and distribution in cortical neurons of the rat brain

  2013cites this paper
• A brief review on experimental fluorosis.

  2013cites this paper
• Impaired Heart Rate Recovery in Patients with Endemic Fluorosis

  2013cites this paper
• an ethical and health issue which affects everyone's health

  2013cites this paper
• Efeitos da suspensão da administração subcrônica de fluoreto de sódio em ratos e seus efeitos amnésicos

  2013cites this paper
• on experimental fluorosis

  2013cites this paper
• Sources and toxicity of fluoride in the environment

  2013cites this paper
• UNIVERSIDADE FEDERAL DO PARÁ INSTITUTO DE CIÊNCIAS BIOLÓGICAS PROGRAMA DE PÓS-GRADUAÇÃO EM NEUROCIÊNCIAS E BIOLOGIA CELULAR

  2012cites this paper
• Combined Impact of Exercise and Temperature in Learning and Memory Performance of Fluoride Toxicated Rats

  2012cites this paper
• Fluoride Toxicity and Status of Serum Thyroid Hormones, Brain Histopathology, and Learning Memory in Rats: A Multigenerational Assessment

  2011cites this paper
• Fluorine—A current literature review. An NRC and ATSDR based review of safety standards for exposure to fluorine and fluorides

  2011cites this paper
• Toxicity effects and action mechanism of fluoride

  2011cites this paper
• Changes of learning and memory ability and brain nicotinic receptors of rat offspring with coal burning fluorosis.

  2010cites this paper
• Alterations of nAChRs and ERK1/2 in the brains of rats with chronic fluorosis and their connections with the decreased capacity of learning and memory.

  2010cites this paper
• Neurobehavioral toxicity produced by sodium fluoride in drinking water of laboratory rats

  2010cites this paper
• Fluoride effects: the two faces of janus.

  2010cites this paper
• Effects of developmental fluoride exposure on rat ultrasonic vocalization, acoustic startle reflex and pre-pulse inhibition.

  2010cites this paper
• Memory Impairment Induced by Sodium Fluoride is Associated with Changes in Brain Monoamine Levels

  2009cites this paper
• Use of the Rey-Osterrieth Complex Figure Test for neurotoxicity evaluation of mixtures in children.

  2009cites this paper
• Decreased learning and memory ability in rats with fluorosis: increased oxidative stress and reduced cholinesterase activity in the brain.

  2009cites this paper
• Subchronic fluoride intake induces impairment in habituation and active avoidance tasks in rats.

  2008cites this paper
• Elucidating the role of the alpha7 subunit of the nicotinic receptor in the etiology of schizophrenia

  2008cites this paper
• Fluoride contents in groundwaters and the main consumed foods (dates and tea) in Southern Algeria region

  2008cites this paper
• Elucidating the Role of the α7 Nicotinic Receptor in the Etiology of Schizophrenia.

  2008cites this paper
• Oxidative stress might be a mechanism connected with the decreased alpha 7 nicotinic receptor influenced by high-concentration of fluoride in SH-SY5Y neuroblastoma cells.

  2008influential citation
• Neurofunctional effects of developmental sodium fluoride exposure in rats.

  2007cites this paper
• My Fluoride Position

  2007cites this paper
• Ingestão cronica de flúor induz prejuízo nos testes de habituação e esquiva ativa em ratos

  2007cites this paper
• Objections and Request for Hearing Docket No. OPP-2005-0174 Sulfuryl fluoride; Pesticide Tolerance. Final Rule.

  2005cites this paper
• Fluoride - toxic and pathologic aspects: review of current literature on some aspects of fluoride toxicity.

  2005cites this paper
• stop Fluoridation Now : New Research on Fluoride ' s Brain and Thyroid Toxicity

  2005cites this paper
• Decreased nicotinic receptors in PC12 cells and rat brains influenced by fluoride toxicity--a mechanism relating to a damage at the level in post-transcription of the receptor genes.

  2004cites this paper
• 50 Reasons to Oppose Fluoridation

  2004cites this paper
• BIOCHEMICAL EFFECTS OF SODIUM FLUORIDE AND ARSENIC TRIOXIDE TOXICITY AND THEIR REVERSAL IN THE BRAIN OF MICE

  2004cites this paper
• Selective decreases of nicotinic acetylcholine receptors in PC12 cells exposed to fluoride.

  2003cites this paper
• Environmental Health Environmental Health Exposure to Fluoridated Water and Attention Deficit Hyperactivity Disorder Prevalence among Children and Adolescents in the United States: an Ecological Association Exposure to Fluoridated Water and Attention Deficit Hyperactivity Disorder Prevalence among C

  year unknowncites this paper
• Quality of the Aquifers Groundwater of the Algerian Northern Sahara (Case of HASSI MESSAOUD).

  year unknowncites this paper