Age-matched comparison reveals early electrocardiography and echocardiography changes in dystrophin-deficient dogs.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Neuromuscular Disorders

• Publication date

  2011-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.nmd.2011.03.010PMID 21570848PMCID PMC3298689
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Muscle Gene Therapy

  2011cited by this paper
• Duchenne Cardiomyopathy Gene Therapy

  2010cited by this paper
• M-mode echocardiographic changes in growing beagles.

  2010cited by this paper
• An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed

  2010cited by this paper
• Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs.

  2010cited by this paper
• The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice.

  2010cited by this paper
• Lack of correlation between canine heart rate and body size in veterinary clinical practice.

  2010cited by this paper
• Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs.

  2010cited by this paper
• Canine dilated cardiomyopathy: a retrospective study of prognostic findings in 367 clinical cases.

  2010cited by this paper
• Gender influences cardiac function in the mdx model of duchenne cardiomyopathy

  2010cited by this paper
• Genotype–phenotype analysis in 2,405 patients with a dystrophinopathy using the UMD–DMD database: a model of nationwide knowledgebase

  2009cited by this paper
• Re-examination of the electrocardiogram in boys with Duchenne muscular dystrophy and correlation with its dilated cardiomyopathy.

  2009cited by this paper
• Evaluation of vascular delivery methodologies to enhance rAAV6-mediated gene transfer to canine striated musculature.

  2009cited by this paper
• Mutational spectrum of DMD mutations in dystrophinopathy patients: application of modern diagnostic techniques to a large cohort

  2009cited by this paper
• Cardiac expression of a mini-dystrophin that normalizes skeletal muscle force only partially restores heart function in aged Mdx mice.

  2009cited by this paper
• Selective Vacuolar Degeneration in Dystrophin-Deficient Canine Purkinje Fibers Despite Preservation of Dystrophin-Associated Proteins With Overexpression of Dp71

  2008cited by this paper
• Prevention of Dystrophin-Deficient Cardiomyopathy in Twenty-One-Month-Old Carrier Mice by Mosaic Dystrophin Expression or Complementary Dystrophin/Utrophin Expression

  2008cited by this paper
• Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines.

  2008cited by this paper
• Holter electrocardiogram should be systematic in Duchenne muscular dystrophy.

  2008cited by this paper
• High incidence of electrocardiogram abnormalities in young patients with duchenne muscular dystrophy.

  2008cited by this paper
• Prevalence of cardiomyopathy in Duchenne and Becker's muscular dystrophy.

  2008cited by this paper
• Adeno-Associated Virus Serotype-9 Microdystrophin Gene Therapy Ameliorates Electrocardiographic Abnormalities in mdx Mice

  2008cited by this paper
• Duchenne muscular dystrophy: how bad is the heart?

  2008cited by this paper
• A single intravenous injection of adeno-associated virus serotype-9 leads to whole body skeletal muscle transduction in dogs.

  2008cited by this paper
• Percutaneous Transendocardial Delivery of Self-complementary Adeno-associated Virus 6 Achieves Global Cardiac Gene Transfer in Canines.

  2008cited by this paper
• Sustained AAV-mediated dystrophin expression in a canine model of Duchenne muscular dystrophy with a brief course of immunosuppression.

  2007cited by this paper
• New approaches in the therapy of cardiomyopathy in muscular dystrophy.

  2007cited by this paper
• Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interd

  2006cited by this paper
• The electrocardiogram of the Beagle dog: reference values and effect of sex, genetic strain, body position and heart rate

  2006cited by this paper
• Challenges and opportunities in dystrophin-deficient cardiomyopathy gene therapy.

  2006cited by this paper
• Entries in the Leiden Duchenne muscular dystrophy mutation database: An overview of mutation types and paradoxical cases that confirm the reading‐frame rule

  2006cited by this paper
• Cardiac involvement in Beagle-based canine X-linked muscular dystrophy in Japan (CXMDJ): electrocardiographic, echocardiographic, and morphologic studies

  2006cited by this paper
• Rapid progression from hypertrophic cardiomyopathy to heart failure in a patient with Becker's muscular dystrophy

  2005cited by this paper
• Canine and feline models of human inherited muscle diseases.

  2005cited by this paper
• Cardiomyopathy in dystrophin-deficient hearts is prevented by expression of a neuronal nitric oxide synthase transgene in the myocardium.

  2005cited by this paper
• Tissue Doppler imaging detects early asymptomatic myocardial abnormalities in a dog model of Duchenne's cardiomyopathy.

  2004cited by this paper
• Allometric scaling of M-mode cardiac measurements in normal adult dogs.

  2004cited by this paper
• Tissue Doppler assessment of diastolic and systolic alterations of radial and longitudinal left ventricular motions in Golden Retrievers during the preclinical phase of cardiomyopathy associated with muscular dystrophy.

  2004cited by this paper
• The dystrophin glycoprotein complex: signaling strength and integrity for the sarcolemma.

  2004cited by this paper
• Full-length dystrophin expression in half of the heart cells ameliorates beta-isoproterenol-induced cardiomyopathy in mdx mice.

  2004cited by this paper
• The Heart in Human Dystrophinopathies

  2003cited by this paper
• Doppler echocardiography in the dog: measurement variability and reproducibility.

  2002cited by this paper
• Is the value of QT dispersion a valid method to foresee the risk of sudden death? A study in Becker patients

  2002cited by this paper
• Prognostic value of electrocardiograms, ventricular late potentials, ventricular arrhythmias, and left ventricular systolic dysfunction in patients with Duchenne muscular dystrophy.

  2002cited by this paper
• Evaluation of four 2-dimensional echocardiographic methods of assessing left atrial size in dogs.

  2000cited by this paper
• QT dispersion in patients with Duchenne-type progressive muscular dystrophy.

  1999cited by this paper
• Manual of Veterinary Echocardiography

  1998cited by this paper
• The role of cytoskeletal proteins in cardiomyopathies.

  1998cited by this paper
• Mutation segregation and rapid carrier detection of X-linked muscular dystrophy in dogs.

  1996cited by this paper
• Non-invasive evaluation of the cardiac function in golden retriever dogs by radionuclide angiography.

  1993cited by this paper
• Recommendations for standards in transthoracic two-dimensional echocardiography in the dog and cat. Echocardiography Committee of the Specialty of Cardiology, American College of Veterinary Internal Medicine.

  1993cited by this paper
• Echocardiographic parameters and indices in the normal Beagle dog

  1992cited by this paper
• Effect of breed and body weight on echocardiographic values in four breeds of dogs of differing somatotype.

  1992cited by this paper
• Duchenne's cardiomyopathy in a canine model: electrocardiographic and echocardiographic studies.

  1991cited by this paper
• The incidence and evolution of cardiomyopathy in Duchenne muscular dystrophy.

  1990cited by this paper
• Development of Duchenne-type cardiomyopathy. Morphologic studies in a canine model.

  1989cited by this paper
• Muscular dystrophy in a litter of golden retriever dogs

  1988cited by this paper
• The homologue of the Duchenne locus is defective in X-linked muscular dystrophy of dogs

  1988cited by this paper
• Canine X-linked muscular dystrophy. An animal model of Duchenne muscular dystrophy: clinical studies.

  1988cited by this paper
• Essentials of canine and feline electrocardiography: interpretation and treatment

  1985cited by this paper
• Cardiac rhythm and conduction in Duchenne's muscular dystrophy: a prospective study of 20 patients.

  1984cited by this paper
• Alterations in regional myocardial metabolism, perfusion, and wall motion in Duchenne muscular dystrophy studied by radionuclide imaging.

  1984cited by this paper
• Cardiac Conduction Abnormalities in Children with Duchenne's Progressive Muscular Dystrophy: Electrocardiographic Features and Morphologic Correlates

  1982cited by this paper
• An Ultrastructural Basis for Electrocardiographic Alterations Associated with Duchenne's Progressive Muscular Dystrophy

  1978cited by this paper
• The distinctive electrocardiogram of Duchenne's progressive muscular dystrophy. An electrocardiographic-pathologic correlative study.

  1967cited by this paper
• The Cardiomyopathy of Progressive Muscular Dystrophy

  1966cited by this paper

• Circulatory CCL2 distinguishes Duchenne muscular dystrophy dogs

  2025cites this paper
• Adeno‐Associated Virus 8 and 9 Myofibre Type/Size Tropism Profiling Reveals Therapeutic Effect of Microdystrophin in Canines

  2025cites this paper
• SERCA2a overexpression improves muscle function in a canine Duchenne muscular dystrophy model

  2024cites this paper
• Extensor carpi ulnaris muscle shows unexpected slow-to-fast fiber-type switch in Duchenne muscular dystrophy dogs

  2021influential citation
• Focus on the road to modelling cardiomyopathy in muscular dystrophy.

  2021cites this paper
• Dystrophin deficiency impairs vascular structure and function in the canine model of Duchenne muscular dystrophy

  2021cites this paper
• Micro-dystrophin gene therapy prevents heart failure in an improved Duchenne muscular dystrophy cardiomyopathy mouse model

  2021cites this paper
• Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MHCK7.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effect on muscle strength

  2021cites this paper
• A Dystrophin Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping

  2021cites this paper
• Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models

  2021cites this paper
• Australian Labradoodle Dystrophinopathy: A Novel Canine Model for the Study of Duchenne Muscular Dystrophy Cardiomyopathy

  2020influential citation
• Parent Project Muscular Dystrophy Females with Dystrophinopathy Conference, Orlando, Florida June 26 – June 27, 2019

  2020cites this paper
• High prevalence of plasma lipid abnormalities in human and canine Duchenne and Becker muscular dystrophies depicts a new type of primary genetic dyslipidemia.

  2020cites this paper
• Laminin-111 protein therapy enhances muscle regeneration and repair in the GRMD dog model of Duchenne muscular dystrophy.

  2019cites this paper
• Alteration in Left Ventricular Contractile Function Develops in Puppies With Duchenne Muscular Dystrophy.

  2019cites this paper
• The Dog Model in the Spotlight: Legacy of a Trustful Cooperation

  2019cites this paper
• Natural History of Cardiomyopathy in Adult Dogs With Golden Retriever Muscular Dystrophy

  2019cites this paper
• Animal Models for Muscle Disease and Muscle Gene Therapy

  2019cites this paper
• Nitric oxide‐dependent attenuation of noradrenaline‐induced vasoconstriction is impaired in the canine model of Duchenne muscular dystrophy

  2018cites this paper
• Characterization of Australian Labradoodle dystrophinopathy.

  2018cites this paper
• Electrocardiography

  2018cites this paper
• Non-invasive evaluation of muscle disease in the canine model of Duchenne muscular dystrophy by electrical impedance myography

  2017cites this paper
• Cardiomyocyte marker expression in dogs with left atrial enlargement due to dilated cardiomyopathy or myxomatous mitral valve disease.

  2017cites this paper
• The golden retriever model of Duchenne muscular dystrophy

  2017cites this paper
• A Five-Repeat Micro-Dystrophin Gene Ameliorated Dystrophic Phenotype in the Severe DBA/2J-mdx Model of Duchenne Muscular Dystrophy

  2017cites this paper
• Dual AAV Gene Therapy for Duchenne Muscular Dystrophy with a 7-kb Mini-Dystrophin Gene in the Canine Model

  2017cites this paper
• Suspected acute myocardial infarction in a dystrophin-deficient dog.

  2016cites this paper
• Canine-Inherited Dystrophinopathies and Centronuclear Myopathies

  2016cites this paper
• AAV-8 Is More Efficient than AAV-9 in Transducing Neonatal Dog Heart

  2015cites this paper
• Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy

  2015cites this paper
• A Translational Pathway Toward a Clinical Trial Using the Second-Generation AAV Micro Dystrophin Vector

  2015cites this paper
• Contemporary Cardiac Issues in Duchenne Muscular Dystrophy

  2015cites this paper
• Duchenne Muscular Dystrophy Gene Therapy in the Canine Model

  2015cites this paper
• Safe and bodywide muscle transduction in young adult Duchenne muscular dystrophy dogs with adeno-associated virus.

  2015cites this paper
• Night Activity Reduction is a Signature Physiological Biomarker for Duchenne Muscular Dystrophy Dogs

  2015cites this paper
• Systemic gene transfer reveals distinctive muscle transduction profile of tyrosine mutant AAV-1, -6, and -9 in neonatal dogs

  2014cites this paper
• Pharmacologic management of Duchenne muscular dystrophy: target identification and preclinical trials.

  2014cites this paper
• Characterization of 65 Epitope-Specific Dystrophin Monoclonal Antibodies in Canine and Murine Models of Duchenne Muscular Dystrophy by Immunostaining and Western Blot

  2014cites this paper
• Long-Term Robust Myocardial Transduction of the Dog Heart from a Peripheral Vein by Adeno-Associated Virus Serotype-8

  2013cites this paper
• Quantitative Phenotyping of Duchenne Muscular Dystrophy Dogs by Comprehensive Gait Analysis and Overnight Activity Monitoring

  2013influential citation
• Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophy.

  2013cites this paper
• Cardiac structure and function in female carriers of a canine model of Duchenne muscular dystrophy.

  2013cites this paper
• Humoral Immunity to AAV-6, 8, and 9 in Normal and Dystrophic Dogs

  2012cites this paper
• Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies

  2012cites this paper
• Progress in gene therapy of dystrophic heart disease

  2012cites this paper
• Dystrophin Deficiency Compromises Force Production of the Extensor Carpi Ulnaris Muscle in the Canine Model of Duchenne Muscular Dystrophy

  2012cites this paper
• A Simplified Immune Suppression Scheme Leads to Persistent Micro-dystrophin Expression in Duchenne Muscular Dystrophy Dogs

  2012influential citation
• Canine Model of Duchenne Muscular Dystrophy.

  year unknowncites this paper