Preclinical Alterations in the Serum of COL(IV)A3(-)/(-) Mice as Early Biomarkers of Alport Syndrome.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Journal of Proteome Research

• Publication date

  2015-11-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1021/acs.jproteome.5b00814PMID 26487288
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Alport syndrome from bench to bedside: the potential of current treatment beyond RAAS blockade and the horizon of future therapies.

  2014cited by this paper
• Site-Specific Glycan Microheterogeneity of Inter-Alpha-Trypsin Inhibitor Heavy Chain H4

  2014cited by this paper
• Global analysis reveals the complexity of the human glomerular extracellular matrix.

  2014cited by this paper
• Diagnosis of Alport syndrome—search for proteomic biomarkers in body fluids

  2013cited by this paper
• Comparative proteomics, network analysis and post-translational modification identification reveal differential profiles of plasma Con A-bound glycoprotein biomarkers in gastric cancer.

  2013cited by this paper
• Ontogenic expression pattern and genetic polymorphisms of the retinol-binding protein 4 (RBP4) gene in Erlang mountainous chickens.

  2013cited by this paper
• Gelsolin: The tail of a molecular gymnast

  2013cited by this paper
• Colorful quality control of chromatographic sample preparation.

  2013cited by this paper
• An update on the pathomechanisms and future therapies of Alport syndrome

  2013cited by this paper
• Alport syndrome—insights from basic and clinical research

  2013cited by this paper
• Functional anatomy of complement factor H.

  2013cited by this paper
• A Secreted Disulfide Catalyst Controls Extracellular Matrix Composition and Function

  2013cited by this paper
• Expert guidelines for the management of Alport syndrome and thin basement membrane nephropathy.

  2013cited by this paper
• LRG1 promotes angiogenesis by modulating endothelial TGFß signalling

  2013cited by this paper
• Chemosensory signals and their receptors in the olfactory neural system.

  2013cited by this paper
• Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury.

  2012cited by this paper
• Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy.

  2012cited by this paper
• Incidence of renal failure and nephroprotection by RAAS inhibition in heterozygous carriers of X-chromosomal and autosomal recessive Alport mutations.

  2012cited by this paper
• Renal cortical hemopexin accumulation in response to acute kidney injury.

  2012cited by this paper
• Outcomes of male patients with Alport syndrome undergoing renal replacement therapy.

  2012cited by this paper
• Balance between apoptosis or survival induced by changes in extracellular-matrix composition in human mesangial cells: a key role for ILK-NFκB pathway

  2012cited by this paper
• Role of the podocyte (and glomerular endothelium) in building the GBM.

  2012cited by this paper
• Clinical practice recommendations for the treatment of Alport syndrome: a statement of the Alport Syndrome Research Collaborative

  2012cited by this paper
• Serum complement factor H is associated with clinical and pathological activities of patients with lupus nephritis.

  2012cited by this paper
• β2‐Glycoprotein I: evolution, structure and function

  2011cited by this paper
• Clinical utility gene card for: Alport syndrome

  2011cited by this paper
• Clinical Significance of Fibroblast-Specific Protein-1 Expression on Podocytes in Patients with Focal Segmental Glomerulosclerosis

  2011cited by this paper
• An alternative view of the proposed alternative activities of hemopexin

  2011cited by this paper
• Evaluation of protein expression in bovine bronchoalveolar fluid following challenge with Mannheimia haemolytica

  2011cited by this paper
• Efficacy and safety of losartan in children with Alport syndrome--results from a subgroup analysis of a prospective, randomized, placebo- or amlodipine-controlled trial.

  2011cited by this paper
• High-Throughput Microarray Detection of Vomeronasal Receptor Gene Expression in Rodents

  2010cited by this paper
• Inter-alpha-trypsin inhibitor heavy chain 4 as a marker of acute rejection in pancreas allotransplantation in pigs.

  2010cited by this paper
• Mass spectrometric characterization of gelsolin isoforms.

  2010cited by this paper
• Alterations of retinol-binding protein 4 species in patients with different stages of chronic kidney disease and their relation to lipid parameters.

  2010cited by this paper
• X-inactivation modifies disease severity in female carriers of murine X-linked Alport syndrome.

  2010cited by this paper
• Heme Scavenging and the Other Facets of Hemopexin

  2010cited by this paper
• Alport syndrome. Molecular genetic aspects.

  2009cited by this paper
• Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism.

  2009cited by this paper
• Acute phase response in animals: a review.

  2009cited by this paper
• Hemopexin down‐regulates LPS‐induced proinflammatory cytokines from macrophages

  2009cited by this paper
• Structure and Function of Inter-α-Trypsin Inhibitor Heavy Chains

  2008cited by this paper
• Serum inter-alpha-trypsin inhibitor and matrix hyaluronan promote angiogenesis in fibrotic lung injury.

  2008cited by this paper
• Adipocytokines and the metabolic complications of obesity.

  2008cited by this paper
• Hemopexin induces nephrin-dependent reorganization of the actin cytoskeleton in podocytes.

  2008cited by this paper
• Spironolactone exhibits direct renoprotective effects and inhibits renal renin-angiotensin-aldosterone system in diabetic rats.

  2008cited by this paper
• Adipokines and Insulin Resistance

  2008cited by this paper
• Searching biomarker candidates in serum using multidimensional native chromatography. II Method evaluation with Alport syndrome and severe inflammation.

  2008cited by this paper
• Mouse podocyte complement factor H: the functional analog to human complement receptor 1.

  2007cited by this paper
• Mouse Inter-Alpha-Trypsin Inhibitor Family Heavy Chain-Related Protein is an Acute Phase Protein Induced by Inflammation

  2006cited by this paper
• Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells.

  2006cited by this paper
• High sodium chloride intake decreases betaine-homocysteine S-methyltransferase expression in guinea pig liver and kidney.

  2005cited by this paper
• Immunodepletion of albumin for two‐dimensional gel detection of new mouse acute‐phase protein and other plasma proteins

  2005cited by this paper
• Cell-specific localization of the sulphydryl oxidase QSOX in rat peripheral tissues

  2005cited by this paper
• Expression of membrane-associated carbonic anhydrase isoforms IV, IX, XII, and XIV in the rabbit: induction of CA IV and IX during maturation.

  2005cited by this paper
• The human complement factor H: functional roles, genetic variations and disease associations.

  2004cited by this paper
• Inter-alpha-trypsin inhibitor, a covalent protein-glycosaminoglycan-protein complex.

  2004cited by this paper
• Antifibrotic, nephroprotective potential of ACE inhibitor vs AT1 antagonist in a murine model of renal fibrosis.

  2004cited by this paper
• Inter-α-trypsin Inhibitor, a Covalent Protein-Glycosaminoglycan-Protein Complex*

  2004cited by this paper
• Regulation of Plasma Hemopexin Activity by Stimulated Endothelial or Mesangial Cells

  2004cited by this paper
• Production of hemopexin by TNF-α stimulated human mesangial cells

  2003cited by this paper
• Preemptive ramipril therapy delays renal failure and reduces renal fibrosis in COL4A3-knockout mice with Alport syndrome.

  2003cited by this paper
• Novel COL4A4 splice defect and in-frame deletion in a large consanguine family as a genetic link between benign familial haematuria and autosomal Alport syndrome.

  2003cited by this paper
• Production of hemopexin by TNF-alpha stimulated human mesangial cells.

  2003cited by this paper
• Alport's syndrome, Goodpasture's syndrome, and type IV collagen.

  2003cited by this paper
• Meta-analysis of genotype-phenotype correlation in X-linked Alport syndrome: impact on clinical counselling.

  2002cited by this paper
• Hemopexins suppress phorbol ester-induced necrosis of polymorphonuclear leucocytes.

  2001cited by this paper
• X-linked Alport syndrome: natural history in 195 families and genotype- phenotype correlations in males.

  2000cited by this paper
• Acute-phase proteins and other systemic responses to inflammation.

  1999cited by this paper
• FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulated.

  1999cited by this paper
• Hepatic and extra-hepatic transcription of inter-alpha-inhibitor family genes under normal or acute inflammatory conditions in rat.

  1998cited by this paper
• Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome.

  1996cited by this paper
• Human inter-alpha-inhibitor family in inflammation: simultaneous synthesis of positive and negative acute-phase proteins.

  1993cited by this paper
• Extrahepatic expression of plasma protein genes during inflammation

  1991cited by this paper
• Clinical and nutritional aspects of changes in acute-phase proteins during inflammation

  1989cited by this paper
• Genetics of classic Alport's syndrome.

  1988cited by this paper
• HEREDITARY FAMILIAL CONGENITAL HAEMORRHAGIC NEPHRITIS

  1927cited by this paper
• HEREDITARY FAMILIAL CONGENITAL HAEMORRHAGIC NEPHRITIS

  1927cited by this paper
• MUTATION IN BRIEF

  year unknowncited by this paper

• Biomarkers for the early diagnosis of Alport syndrome and associated kidney damage

  2025influential citation
• Preclinical Detection of Early Glomerular Injury in Children with Kidney Diseases—Independently of Usual Markers of Kidney Impairment and Inflammation

  2024cites this paper
• Urinary Protein-Biomarkers Reliably Indicate Very Early Kidney Damage in Children With Alport Syndrome Independently of Albuminuria and Inflammation

  2023influential citation
• Radiation nephropathy: Mechanisms of injury and recovery in a murine model.

  2023cites this paper
• Potential Renal Damage Biomarkers in Alport Syndrome—A Review of the Literature

  2022cites this paper
• A novel frameshift mutation of COL4A5 in a Chinese family with presumed IgA nephropathy and chronic glomerulonephritis

  2020cites this paper
• Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome

  2020cites this paper
• A next generation setup for pre-fractionation of non-denatured proteins reveals diverse albumin proteoforms each carrying several post-translational modifications

  2019cites this paper
• Traditional Renal Biomarkers and New Approaches to Diagnostics

  2018cites this paper
• Alport syndrome: facts and opinions

  2017cites this paper
• ISN Nexus 2016 Symposia: Translational Immunology in Kidney Disease—The Berlin Roadmap

  2016cites this paper
• The intricacy of biomarker complexity–the identification of a genuine proteomic biomarker is more complicated than believed

  2016cites this paper
• Acute phase proteins as promising biomarkers: Perspectives and limitations for human and veterinary medicine

  2016influential citation