Intraarterial Delivery of Adenovirus Vectors and Liposome-DNA Complexes to Experimental Brain Neoplasms

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Human Gene Therapy

• Publication date

  1999-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/10430349950019093PMID 10022555
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Direct Exposure of Mouse Spermatogenic Cells to High Doses of Adenovirus Gene Therapy Vector Does Not Result in Germ Cell Transduction

  2000cited by this paper
• Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects.

  2000cited by this paper
• Gene therapy for brain tumors

  2000cited by this paper
• Characterization of a Canine Glioma Cell Line As Related to Established Experimental Brain Tumor Models

  2000cited by this paper
• Correction of Acid beta-Galactosidase Deficiency in GM1 Gangliosidosis Human Fibroblasts by Retrovirus VectorMediated Gene Transfer: Higher Efficiency of Release and Cross-Correction by the Murine Enzyme

  2000cited by this paper
• Delivery of Lipoplexes for Genotherapy of Solid Tumours: Role of Vascular Endothelial Cells

  2000cited by this paper
• Emerging therapeutic targets for glioblastoma multiform

  1999cited by this paper
• Selective delivery of herpes virus vectors to experimental brain tumors using RMP-7

  1999cited by this paper
• Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors

  1998cited by this paper
• Gene Transfer into Mammalian Cells Using Histone-Condensed Plasmid DNA

  1996cited by this paper
• Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: a phase I trial.

  1996cited by this paper
• Unlocking the blood-brain barrier: a role for RMP-7 in brain tumor therapy.

  1996cited by this paper
• Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: long-term follow-up by magnetic resonance imaging.

  1996cited by this paper
• Liposomal delivery of the herpes simplex virus thymidine kinase gene in glioma: improvement of cell sensitization to ganciclovir.

  1996cited by this paper
• In vivo gene transfer of insulin gene into neonatal rats by the HVJ-liposome method resulted in sustained transgene expression.

  1996cited by this paper
• A continuous intracerebral gene delivery system for in vivo liposome-mediated gene therapy.

  1996cited by this paper
• Treatment of Advanced CNS Malignancies with the Recombinant Adenovirus H5.010RSVTK: A Phase I Trial. University of Pennsylvania Medical Center, Philadelphia

  1996cited by this paper
• Long-Term Survival in a Rodent Model of Disseminated Brain Tumors by Combined Intrathecal Delivery of Herpes Vectors and Ganciclovir Treatment

  1996cited by this paper
• A New Cationic Liposome DNA Complex Enhances the Efficiency of Arterial Gene Transfer In Vivo

  1996cited by this paper
• Herpes Simplex Virus Thymidine Kinase Gene Therapy for Rat Malignant Brain Tumors

  1996cited by this paper
• Improved Cationic Lipid Formulations for In Vivo Gene Therapy

  1995cited by this paper
• A novel nonviral cytoplasmic gene expression system and its implications in cancer gene therapy.

  1995cited by this paper
• Selective Uptake of Viral and Monocrystalline Particles Delivered Intra-Arterially to Experimental Brain Neoplasms

  1995cited by this paper
• The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants.

  1995cited by this paper
• Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption.

  1995cited by this paper
• Non-viral approaches to gene therapy.

  1995cited by this paper
• Adenovirally mediated gene transfer into experimental solid brain tumors and leptomeningeal cancer cells.

  1995cited by this paper
• Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats.

  1995cited by this paper
• Gene expression from recombinant viral vectors in the central nervous system after blood-brain barrier disruption.

  1995cited by this paper
• Gene Therapy for Brain Tumors

  1995cited by this paper
• Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations.

  1994cited by this paper
• Bradykinin Selectively Opens Blood-Tumor Barrier in Experimental Brain Tumors

  1994cited by this paper
• Efficient transfection of human interferon-beta gene to human glioma cells by means of cationic multilamellar liposomes coupled with a monoclonal antibody [corrected].

  1994cited by this paper
• Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene.

  1994cited by this paper
• Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo.

  1994cited by this paper
• Virus-Mediated Genetic Treatment of Rodent Gliomas

  1994cited by this paper
• High‐Efficiency Gene Transfer Mediated by Adenovirus‐Polylysine‐DNA Complexes

  1994influential reference
• Strategies to achieve targeted gene delivery via the receptor-mediated endocytosis pathway.

  1994cited by this paper
• Gene Transfer into Experimental Brain Tumors Mediated by Adenovirus, Herpes Simplex Virus, and Retrovirus Vectors

  1994cited by this paper
• Adenovirus‐mediated gene therapy of experimental gliomas

  1994cited by this paper
• Non-viral approaches to gene therapy.

  1993cited by this paper
• Safety and short-term toxicity of a novel cationic lipid formulation for human gene therapy.

  1993cited by this paper
• Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor.

  1992cited by this paper
• Liposomes for the transformation of eukaryotic cells.

  1991influential reference
• Delivery of ultraviolet-inactivated 35S-herpesvirus across an osmotically modified blood-brain barrier.

  1991cited by this paper
• Lineage-independent determination of cell type in the embryonic mouse retina.

  1990cited by this paper
• Brain tumor epidemiology, growth, and invasion.

  1990cited by this paper
• Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA.

  1989cited by this paper
• A commentary on the biology and growth kinetics of low-grade and high-grade gliomas.

  1984cited by this paper
• The fine structure of blood vessels in ethylnitrosourea-induced tumours of the rat nervous system: with special reference to the breakdown of the blood-brain barrier.

  1976cited by this paper

• Advances in CNS drug delivery strategies to cross the blood-brain barrier

  2025cites this paper
• Nanostructured Lipid Carriers (NLC): A Targeting Approach to the Brain via Intranasal Administration

  2020cites this paper
• Current approaches and prospective drug targeting to brain

  2020cites this paper
• Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis

  2019cites this paper
• Brain Tumor Models for Cancer Therapy

  2018cites this paper
• Progress in brain targeting drug delivery system by nasal route

  2017cites this paper
• Nanobiotechnology-based delivery strategies: New frontiers in brain tumor targeted therapies.

  2016cites this paper
• Intra-arterial delivery of AAV vectors to the mouse brain after mannitol mediated blood brain barrier disruption.

  2014cites this paper
• Targeted Gene Delivery: Importance of Administration Routes

  2013cites this paper
• Development and characterization of artificial viruses for gene therapy

  2013cites this paper
• Angiogenesis in Brain Tumors

  2013cites this paper
• Intracarotid Drug Delivery: Revisiting the Past or Looking into the Future

  2010cites this paper
• Strategy for effective brain drug delivery.

  2010cites this paper
• Drug Delivery to the Central Nervous System

  2010cites this paper
• Dendrimer nanocarriers as versatile vectors in gene delivery.

  2009cites this paper
• Delivery of peptide and protein drugs over the blood-brain barrier.

  2009cites this paper
• Safety and Short-term Toxicity of a Novel Cationic Lipid Formulation for Human Gene Therapy

  2009cites this paper
• Intracarotid Delivery of Drugs: The Potential and the Pitfalls

  2008cites this paper
• Cancer angiogenesis: Targeting the heel of Achilles

  2008cites this paper
• Cancer angiogenesis: targeting the heel of Achilles.

  2008cites this paper
• Cancer gene therapy with targeted adenoviruses

  2008cites this paper
• Cancer gene therapy with targeted adenoviruses.

  2008cites this paper
• The Potential and the Pitfalls

  2008cites this paper
• Nonviral Approaches for Neuronal Delivery of Nucleic Acids

  2007cites this paper
• Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis

  2007cites this paper
• A new method for superselective middle cerebral artery infusion in the rat.

  2007cites this paper
• Intra-arterial Drug Delivery: A Concise Review

  2007cites this paper
• Intravenously administered oligonucleotides can be delivered to conducting airway epithelium via the bronchial circulation

  2006cites this paper
• CHAPTER 10 – Delivery of Molecular Therapeutics into the CNS and their Distribution within the Brain

  2006cites this paper
• Gene technology based therapies in the brain.

  2006cites this paper
• CHAPTER 4 – Brain Tumor Models for Cancer Therapy

  2006cites this paper
• Striking out at disseminated metastases: the systemic delivery of oncolytic viruses.

  2006cites this paper
• Chapter 14 – Gene Therapy for Malignant Gliomas

  2005cites this paper
• Intra-arterial delivery of endostatin gene to brain tumors prolongs survival and alters tumor vessel ultrastructure

  2004cites this paper
• Direct Exposure of Mouse Spermatozoa to Very High Concentrations of a Serotype-2 Adeno-Associated Virus Gene Therapy Vector Fails to Lead to Germ Cell Transduction

  2004cites this paper
• Vascular microenvironment in gliomas.

  2004cites this paper
• Lipoplex-mediated delivery of nucleic acids: factors affecting in vivo transfection

  2004cites this paper
• Tumour Angiogenesis, Vascular Biology and Enhanced Drug Delivery

  2004cites this paper
• Intravascular Delivery of Neural Stem Cell Lines to Target Intracranial and Extracranial Tumors of Neural and Non-Neural Origin

  2003cites this paper
• Molecular therapy: clinical applications. intra-arterial adenoviruses administration.

  2003cites this paper
• Seminiferous tubule cannulation (STC): a new, sensitive technique for detecting gene transfer in developing sperm

  2003cites this paper
• Improving anti-angiogenic therapy via selective delivery of cationic liposomes to tumour vasculature.

  2003cites this paper
• Cationic lipids for transfection.

  2003cites this paper
• Nonviral approaches satisfying various requirements for effective in vivo gene therapy.

  2002cites this paper
• Oncolytic adenoviruses for treatment of brain tumours

  2002cites this paper
• Vehicles for oligonucleotide delivery to tumours

  2002cites this paper
• Biochemical and biophysical characteristics of lipoplexes pertinent to solid tumour gene therapy.

  2002cites this paper
• Cationic liposomes conjugation to recombinant adenoviral vectors containing herpes simplex virus thymidine kinase gene followed by ganciclovir treatment reduces viral antigenicity and maintains antitumor activity in mouse experimental glioma models

  2002cites this paper
• Routes of vector application for brain tumor gene therapy Review Article

  2001influential citation
• Direct exposure of mouse ovaries and oocytes to high doses of an adenovirus gene therapy vector fails to lead to germ cell transduction.

  2001cites this paper
• Nonviral Vectors in the New Millennium: Delivery Barriers in Gene Transfer

  2001cites this paper
• Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects.

  2000cites this paper
• Combination gene therapy using multiple immunomodulatory genes transferred by a defective infectious single-cycle herpes virus in squamous cell cancer

  2000cites this paper
• Correction of Acid beta-Galactosidase Deficiency in GM1 Gangliosidosis Human Fibroblasts by Retrovirus VectorMediated Gene Transfer: Higher Efficiency of Release and Cross-Correction by the Murine Enzyme

  2000cites this paper
• Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.

  2000cites this paper
• Characterization of a Canine Glioma Cell Line As Related to Established Experimental Brain Tumor Models

  2000cites this paper
• Direct Exposure of Mouse Spermatogenic Cells to High Doses of Adenovirus Gene Therapy Vector Does Not Result in Germ Cell Transduction

  2000cites this paper
• Delivery of Lipoplexes for Genotherapy of Solid Tumours: Role of Vascular Endothelial Cells

  2000cites this paper
• Vascular Microenvironment in Gliomas

  2000cites this paper
• Emerging therapeutic targets for glioblastoma multiform

  1999cites this paper
• Genetic Engineering for CNS Regeneration

  1999cites this paper
• A review of gene therapy for the treatment of central nervous system tumors.

  1999cites this paper