Positive regulation of jun/AP-1 by E1A

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Molecular and Cellular Biology

• Publication date

  1991-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/mcb.11.1.192-201.1991PMID 1824713PMCID PMC359609
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein.

  1990cited by this paper
• Differential activation of the E2F transcription factor by the adenovirus EIa and EIV products in F9 cells.

  1990cited by this paper
• Ectopic expression of c‐jun leads to differentiation of P19 embryonal carcinoma cells.

  1990cited by this paper
• Cross-talk in signal transduction: TPA-inducible factor jun/AP-1 activates cAMP-responsive enhancer elements.

  1990cited by this paper
• Distinct adenosine 3',5'-monophosphate and phorbol ester-responsive signal transduction pathways converge at the level of transcriptional activation by the interactions of DNA-binding proteins.

  1989cited by this paper
• Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains.

  1989cited by this paper
• The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation.

  1989cited by this paper
• ras-induced neuronal differentiation of PC12 cells: possible involvement of fos and jun

  1989cited by this paper
• Characterization of junD: a new member of the jun proto‐oncogene family.

  1989cited by this paper
• The adenovirus early region 4 open reading frame 6/7 protein regulates the DNA binding activity of the cellular transcription factor, E2F, through a direct complex.

  1989cited by this paper
• Distinguishable promoter elements are involved in transcriptional activation by E1a and cyclic AMP.

  1989cited by this paper
• Transcription activation by the adenovirus E1a protein

  1989cited by this paper
• Multiple sequence elements in the c-fos promoter mediate induction by cAMP.

  1989cited by this paper
• jun-D: a third member of the jun gene family.

  1989cited by this paper
• TPA can overcome the requirement for EIa and together act synergistically in stimulating expression of the adenovirus EIII promoter.

  1989cited by this paper
• Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers.

  1989cited by this paper
• Induction of transcription factor AP-1 by adenovirus E1A protein and cAMP.

  1989cited by this paper
• An AP1-binding site in the c-fos gene can mediate induction by epidermal growth factor and 12-O-tetradecanoyl phorbol-13-acetate

  1989cited by this paper
• Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter

  1989cited by this paper
• The adenovirus-5 12S E1a protein, but not the 13S induces expression of the endoA differentiation marker in F9 cells.

  1989cited by this paper
• Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element.

  1988cited by this paper
• Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription.

  1988cited by this paper
• Structural determinants for transcriptional activation by cAMP-responsive DNA elements.

  1988cited by this paper
• A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1.

  1988cited by this paper
• Purification and functional characterization of a cellular transcription factor that binds to an enhancer element within the adenovirus early EIIa promoter.

  1988cited by this paper
• DNA‐binding properties of an adenovirus 289R E1A protein.

  1988cited by this paper
• cAMP acts in synergy with E1A protein to activate transcription of the adenovirus early genes E4 and E1A.

  1988cited by this paper
• Cyclic AMP induction of early adenovirus promoters involves sequences required for E1A trans-activation.

  1988cited by this paper
• Interaction of a common cellular transcription factor, ATF, with regulatory elements in both E1a- and cyclic AMP-inducible promoters.

  1988cited by this paper
• Fos and Jun: the AP-1 connection.

  1988cited by this paper
• Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

  1988cited by this paper
• Expression of a human placental alkaline phosphatase gene in transfected cells: use as a reporter for studies of gene expression.

  1988cited by this paper
• Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts.

  1988cited by this paper
• Cellular transcription factor binds to adenovirus early region promoters and to a cyclic AMP response element

  1988cited by this paper
• A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing.

  1988cited by this paper
• DNA binding activities of three murine Jun proteins: stimulation by Fos.

  1988cited by this paper
• Induction of proto-oncogene JUN/AP-1 by serum and TPA

  1988cited by this paper
• Activation of a preexisting cellular factor as a basis for adenovirus E1A-mediated transcription control.

  1988influential reference
• The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1.

  1988influential reference
• c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities.

  1988cited by this paper
• Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

  1988cited by this paper
• The role of the leucine zipper in the fos–jun interaction

  1988cited by this paper
• The CGTCA sequence motif is essential for biological activity of the vasoactive intestinal peptide gene cAMP-regulated enhancer.

  1988cited by this paper
• A gene activated by growth factors is related to the oncogene v-jun.

  1988cited by this paper
• Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor.

  1988cited by this paper
• Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1.

  1987cited by this paper
• Promoter trans-activation of protooncogenes c-fos and c-myc, but not c-Ha-ras, by products of adenovirus early region 1A.

  1987cited by this paper
• Two promoter-specific host factors interact with adjacent sequences in an EIA-inducible adenovirus promoter.

  1987cited by this paper
• Multiple functional domains in the adenovirus E1A gene.

  1987cited by this paper
• The adenovirus Ela gene induces differentiation of F9 teratocarcinoma cells

  1987cited by this paper
• Identification of factors that interact with the E1A-inducible adenovirus E3 promoter.

  1987cited by this paper
• Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element.

  1987cited by this paper
• Proto-oncogene fos: complex but versatile regulation.

  1987cited by this paper
• Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements.

  1987cited by this paper
• Modification of fos proteins: phosphorylation of c-fos, but not v-fos, is stimulated by 12-tetradecanoyl-phorbol-13-acetate and serum

  1987cited by this paper
• Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor.

  1987influential reference
• Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements

  1987cited by this paper
• The nerve growth factor: thirty‐five years later.

  1987cited by this paper
• An adenovirus E1a protein region required for transformation and transcriptional repression.

  1986influential reference
• Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

  1986cited by this paper
• Adenovirus promoters and E1A transactivation.

  1986cited by this paper
• Establishment of a differentiated mesodermal line from P19 EC cells expressing functional PDGF and EGF receptors.

  1986cited by this paper
• Induction of the proto-oncogene fos by nerve growth factor.

  1985cited by this paper
• Adenovirus E1a proteins repress transcription from the SV40 early promoter.

  1985cited by this paper
• Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein

  1985cited by this paper
• Clonal variants of differentiated P19 embryonal carcinoma cells exhibit epidermal growth factor receptor kinase activity.

  1985cited by this paper
• Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation.

  1985cited by this paper
• Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation.

  1985cited by this paper
• The adenovirus‐2 early EIIa transcription unit possesses two overlapping promoters with different sequence requirements for EIa‐dependent stimulation.

  1985cited by this paper
• Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family.

  1985cited by this paper
• Repression of the immunoglobulin heavy chain enhancer by the adenovirus-2 E1A products.

  1985cited by this paper
• Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

  1985cited by this paper
• HeLa cell beta-tubulin gene transcription is stimulated by adenovirus 5 in parallel with viral early genes by an E1a-dependent mechanism

  1984cited by this paper
• Individual products of the adenovirus 12S and 13S EIa mRNAs stimulate viral EIIa and EIII expression at the transcriptional level.

  1984cited by this paper
• Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

  1984influential reference
• Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

  1984cited by this paper
• Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.

  1983cited by this paper
• Eukaryotic gene transcription with purified components.

  1983cited by this paper
• Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection

  1983cited by this paper
• Cis-acting induction of adenovirus transcription.

  1983cited by this paper
• Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

  1983cited by this paper
• FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA

  1982cited by this paper
• Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line

  1982cited by this paper
• Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

  1982cited by this paper
• Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis.

  1981cited by this paper
• Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs.

  1979cited by this paper
• Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

  1979cited by this paper
• An adenovirus type 5 early gene function regulates expression of other early viral genes.

  1979influential reference
• The CGTCA sequence motif is essential for biological activity of the vasoactive intestinal peptide gene cAMP-regulated enhancer (neuropeptide/gene

  year unknowncited by this paper

• Tyrosine hydroxylase gene promoter activity is upregulated in female catecholaminergic neuroblastoma cells following activation of a Gαq-coupled designer receptor.

  2022cites this paper
• Immediate-early transcriptional response to insulin receptor stimulation.

  2021cites this paper
• Sprouty is a cytoplasmic target of adenoviral E1A oncoproteins to regulate the receptor tyrosine kinase signalling pathway

  2011cites this paper
• Tumor Suppression and Sensitization to Taxol Induces Apoptosis of EIA in Breast Cancer Cells

  2005cites this paper
• The X-gene of human hepatitis B virus transactivates the c-jun and α-fetoprotein genes

  2005cites this paper
• Latent adenoviral infection induces production of growth factors relevant to airway remodeling in COPD.

  2004cites this paper
• E1A-mediated suppression of EGFR expression and induction of apoptosis in head and neck squamous carcinoma cell lines

  2003cites this paper
• Transgenic Expression in Mouse Lung Reveals Distinct Biological Roles for the Adenovirus Type 5 E1A 243- and 289-Amino-Acid Proteins

  2002cites this paper
• Identification of the full-length huntingtin- interacting protein p231HBP/HYPB as a DNA-binding factor.

  2001cites this paper
• E1A: Tumor suppressor or oncogene? Preclinical and clinical investigations ofE1A gene therapy

  2001cites this paper
• Zinc finger and carboxyl regions of adenovirus E1A 13S CR3 are important for transactivation of the cytomegalovirus major immediate early promoter by adenovirus.

  2000cites this paper
• Axl-Gas6 Interaction Counteracts E1A-Mediated Cell Growth Suppression and Proapoptotic Activity

  1999cites this paper
• The role of Homeobox genes in normal hematopoiesis and hematological malignancies

  1999cites this paper
• Dual action of the adenovirus E1A 243R oncoprotein on the human proliferating cell nuclear antigen promoter: repression of transcriptional activation by p53

  1999cites this paper
• The coactivators p300 and CBP have different functions during the differentiation of F9 cells

  1999cites this paper
• The erbB2 gene as a cancer therapeutic target and the tumor- and metastasis-suppressing function of E1A

  1998cites this paper
• induction of cellular immediate-early genes . to its receptor , VLA-2 , is required for the Echovirus 1 replication , not only virus binding

  1997cites this paper
• A cis-acting element 7 bp upstream of the ESF-1-binding motif is involved in E1A 13S autoregulation of the adenovirus 12 TS2 promoter.

  1997cites this paper
• Peripheral Noxious Stimulation Induces CREM Expression in Dorsal Horn: Involvement of Glutamate

  1997cites this paper
• Echovirus 1 replication, not only virus binding to its receptor, VLA-2, is required for the induction of cellular immediate-early genes

  1997cites this paper
• Repression of c-Jun-induced mouse major histocompatibility class I promoter (H-2Kb) activity by the Adenovirus type 12-unique 52R E1A protein.

  1996cites this paper
• Altered AP-1/ATF complexes in adenovirus-E1-transformed cells due to EIA-dependent induction of ATF3.

  1996cites this paper
• The adenoviral transcription factor, E1A 13S, trans-activates the human tumor necrosis factor-alpha promoter.

  1996cites this paper
• Jun: transcription factor and oncoprotein

  1996cites this paper
• Adenovirus E1A downregulates cJun- and JunB-mediated transcription by targeting their coactivator p300

  1996cites this paper
• Adenovirus E 1 A Downregulates cJun-and JunB-Mediated Transcription by Targeting Their Coactivator p 300

  1996cites this paper
• Adenovirus 5 E1A induced differentiation of P19 embryonal carcinoma cells requires binding to p300.

  1995cites this paper
• Modulation of gene expression by adenovirus transformation.

  1995cites this paper
• Regulation of viral and cellular gene expression by E1A proteins encoded by the oncogenic adenovirus type 12.

  1995cites this paper
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  1995cites this paper
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  1995cites this paper
• Induction by adenovirus-5 E1A of the differentiation phenotype of F9 teratocarcinoma cells involves a conserved region (CR1) of E1A.

  1995cites this paper
• Adenovirus E1A antagonizes both negative and positive growth signals elicited by transforming growth factor beta 1.

  1995cites this paper
• Differential induction and regulation of c-jun, junB, junD and c-fos by human papillomavirus type 11 E5a oncoprotein.

  1995cites this paper
• Induction of the mitogen-activated p70 S6 kinase by adenovirus E1A.

  1995cites this paper
• Adenovirus E1A functions as a cofactor for retinoic acid receptor beta (RAR beta) through direct interaction with RAR beta

  1995cites this paper
• Phosphorylation of the adenovirus E1A‐associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cells.

  1995cites this paper
• Neuronal expression of AP-1 proteins in excitotoxic-neurodegenerative disorders and following nerve fiber lesions

  1995cites this paper
• Modulation of AP‐1/ATF transcription factor activity by the adenovirus‐e1a oncogene products

  1995cites this paper
• Goals for signal transduction pathways: linking up with transcriptional regulation.

  1994cites this paper
• Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains

  1994cites this paper
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  1994cites this paper
• The X-gene of human hepatitis B virus transactivates the c-jun and alpha-fetoprotein genes.

  1994cites this paper
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  1994cites this paper
• Adenovirus e1a proteins and transformation (review).

  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1992cites this paper
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  1992cites this paper
• Transcriptional regulation of the c‐jun gene by retinoic acid and E1A during differentiation of F9 cells.

  1992cites this paper
• Biological and biochemical characteristics of a series of human uveal and cutaneous melanomas

  1992cites this paper
• Oncogenes and cell proliferation

  1992cites this paper
• Activation of Jun/AP-1 by protein kinase A.

  1992cites this paper
• Expression of matrix metalloproteinase genes in transformed rat cell lines of high and low metastatic potential.

  1992cites this paper
• Transformation and transactivation suppressor activity of the c-Jun leucine zipper fused to a bacterial repressor.

  1992cites this paper
• SV40 large T inhibits myogenic differentiation partially through inducing c-jun.

  1992cites this paper
• Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1

  1992cites this paper
• Alterations in the levels of expression of specific cellular genes in adenovirus-infected and -transformed cells.

  1992cites this paper
• Cell‐specific inhibitory and stimulatory effects of Fos and Jun on transcription activation by nuclear receptors.

  1991cites this paper
• Analysis of the specificity and mechanism of transcriptional activation of the human hsp70 gene during infection by DNA viruses

  1991cites this paper
• The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site

  1991cites this paper
• Differential regulation of JunB and JunD by adenovirus type 5 and 12 E1A proteins.

  1991cites this paper
• Transcriptional control of c-jun by retinoic acid.

  1991cites this paper
• Interactions between adenovirus E1A and members of the AP-1 family of cellular transcription factors.

  1991cites this paper
• Adenovirus E4orf4 Protein Reduces Phosphorylation of c-Fos and ElA

  year unknowncites this paper