Effects of Chronic Vanadate Administration in the STZ-Induced Diabetic Rat: The Antihyperglycemic Action of Vanadate Is Attributable Entirely to Its Suppression of Feeding

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Diabetes

• Publication date

  1994-01-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.2337/diab.43.1.9PMID 8262323
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intense exercise and food restriction cause similar hypothalamic neuropeptide Y increases in rats.

  1993cited by this paper
• Abstracts of Communications

  1993cited by this paper
• Oral Vanadate Reduces Na+-Dependent Glucose Transport in Rat Small Intestine

  1993influential reference
• Peripheral insulin administration attenuates the increase in neuropeptide Y concentrations in the hypothalamic arcuate nucleus of fasted rats.

  1992cited by this paper
• Effects of vanadate on glycolytic enzymes and malic enzyme in insulin-dependent and -independent tissues of diabetic rats.

  1992influential reference
• Insulin deficiency is a specific stimulus to hypothalamic neuropeptide Y: a comparison of the effects of insulin replacement and food restriction in streptozocin-diabetic rats.

  1992influential reference
• Insulin in the brain: a hormonal regulator of energy balance.

  1992influential reference
• Neuropeptide Y release from the paraventricular nucleus increases in association with hyperphagia in streptozotocin-induced diabetic rats.

  1992cited by this paper
• Inhibition of hypothalamic neuropeptide Y gene expression by insulin.

  1992influential reference
• Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food.

  1991cited by this paper
• Acute fenfluramine administration reduces neuropeptide Y concentrations in specific hypothalamic regions of the rat: possible implications for the anorectic effect of fenfluramine.

  1991cited by this paper
• Neuropeptides and intestinal tract in the control of glucose Homeostasis Hypothalamic regulatory peptides and the regulation of food intake and energy balance: signals or noise?

  1991influential reference
• Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism.

  1991cited by this paper
• Insulin-like effect of vanadate on malic enzyme and glucose-6-phosphate dehydrogenase activities in streptozotocin-induced diabetic rat liver.

  1991cited by this paper
• Central insulin administration reduces neuropeptide Y mRNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) Zucker rats.

  1991influential reference
• Vanadate normalizes hyperglycemia in two mouse models of non-insulin-dependent diabetes mellitus.

  1991cited by this paper
• Unchanged hypothalamic neuropeptide Y concentrations in hyperphagic, hypoglycemic rats: evidence for specific metabolic regulation of hypothalamic NPY.

  1991cited by this paper
• Rapid and localized alterations of neuropeptide Y in discrete hypothalamic nuclei with feeding status.

  1990cited by this paper
• Neuropeptide-Y concentration in microdissected hypothalamic regions and in vitro release from the medial basal hypothalamus-preoptic area of streptozotocin-diabetic rats with and without insulin substitution therapy.

  1990influential reference
• Increased hypothalamic content of preproneuropeptide-Y messenger ribonucleic acid in streptozotocin-diabetic rats.

  1990cited by this paper
• Interregional Elderly Migration and Population Redistribution in Four Industrialized Countries

  1990cited by this paper
• Insulin-Mimetic Effects of Vanadate: Possible Implications for Future Treatment of Diabetes

  1990cited by this paper
• Elevated Neuropeptide Y Concentrations in the Central Hypothalamus of the Spontaneously Diabetic BB/E Wistar Rat

  1989cited by this paper
• Increased Neuropeptide Y Concentrations in Specific Hypothalamic Regions of Streptozocin-Induced Diabetic Rats

  1989influential reference
• Long-Term Effects of Vanadyl Treatment on Streptozocin-Induced Diabetes in Rats

  1989influential reference
• Insulin-like effects of vanadate on glucokinase activity and fructose 2,6-bisphosphate levels in the liver of diabetic rats.

  1988cited by this paper
• Increased Hypothalamic Neuropeptide Y Concentrations in Diabetic Rat

  1988cited by this paper
• Effect of neuropeptide Y on ingestive behaviors in the rat.

  1987cited by this paper
• Neuropeptide regulation of appetite and weight.

  1987cited by this paper
• Effects of chronic administration of vanadate to the rat on the sensitivity of glycolysis and glycogen synthesis in skeletal muscle to insulin.

  1987cited by this paper
• Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. Characterization and mode of action.

  1987influential reference
• Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity.

  1986cited by this paper
• Interaction of vanadate with phenol and tyrosine: implications for the effects of vanadate on systems regulated by tyrosine phosphorylation.

  1986cited by this paper
• Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats.

  1985influential reference
• An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat.

  1985cited by this paper
• Insulin-like stimulation of glucose oxidation in rat adipocytes by vanadyl (IV) ions

  1980cited by this paper
• The insulin-mimetic effects of vanadate in isolated rat adipocytes. Dissociation from effects of vanadate as a (Na+-K+)ATPase inhibitor.

  1980cited by this paper
• Effects of vanadium on glucose metabolism in vitro.

  1979cited by this paper

• Adsorption Behavior and Mechanism of MnMgAl-Layered Double Hydroxide for the Removal of V(V): Experiments and DFT Calculation

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• Antidepressant-like effect of sodium orthovanadate in a mouse model of chronic unpredictable mild stress.

  2021cites this paper
• Delineating Vanadium (V) Ecological Distribution, Its Toxicant Potential, and Effective Remediation Strategies from Contaminated Soils

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• Effects of Insulin and Insulin-Mimetics on mRNA Levels of c-fos and c-jun in Primary Rat Hepatocytes in Culture

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• Toxicological Evaluation of Brassica napus Extract Containing Vanadium, Nutricultured in Jeju Water

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• Antidiabetic, Antioxidant, Antibacterial, and Antifungal Activities of Vanadyl Schiff Base Complexes

  2018cites this paper
• The Molecular Mechanisms and Rational Design of Anti-Diabetic Vanadium Compounds.

  2015cites this paper
• Is the Hypoglycemic Action of Vanadium Compounds Related to the Suppression of Feeding?

  2014cites this paper
• /RQJWHUP(IøFDF\DQG6DIHW\RI9DQDGLXPLQWKH7UHDWPHQWRI Type 1 Diabetes

  2013cites this paper
• Long- term efficacy and safety of vanadium in the treatment of type 1 diabetes.

  2013cites this paper
• The Effect of Extract Powder from Fresh and Black Garlic on Main Components in Serum and Organs of Streptozotocin-Induced Diabetic Rats

  2013cites this paper
• The Effect of Extract Powder from Fresh and Black Garlic on Main Components in Serum and Organs of Streptozotocin-Induced Diabetic Rats

  2013cites this paper
• Effect of Artemisia iwayomogi Ethanol Extract on Hypoglycemic and Antioxidant Activities in Diabetic Rats

  2012cites this paper
• A tea/vanadate decoction delivered orally over 14 months to diabetic rats induces long-term glycemic stability without organ toxicity.

  2012cites this paper
• Effect of Soybeans, Chungkukjang, and Doenjang on Blood Glucose and Serum Lipid Profile in Streptozotocin-induced Diabetic Rats

  2012cites this paper
• Antihyperglycemic of Gleditschiae Spina Extracts in Streptozotocin-Nicotinamide Induced Type 2 Diabetic Rats

  2011cites this paper
• Streptozotocin-Nicotinamide로 유도된 제2형 당뇨모델 쥐에서 조각자( Gleditschiae Spina) 추출물의 항당뇨효과

  2011cites this paper
• Antioxidant enzyme activity and lipid peroxidation in the blood of rats co-treated with vanadium (V+5) and chromium (Cr+3)

  2010influential citation
• Anti-diabetic effect of material fermented using rice bran and soybean as the main ingredient by Bacillus sp.

  2010cites this paper
• Effects of Compositae Plants on Plasma Glucose and Lipid Level in Streptozotocin Induced Diabetic Rats

  2009cites this paper
• COMPARISON OF THE EFFECTS OF SODIUM METAVANADATE AND ZINC SULFATE SUPPLEMENTATION ON LIPID AND GLUCOSE IN PATIENTS WITH TYPE 2 DIABETES

  2009cites this paper
• The Effects of Chungkookjang Biopolymer on Blood Glucose and Serum Lipid Lowering in Streptozotocin-Induced Diabetic Rats

  2008cites this paper
• Effect of sodium metavanadate supplementation on lipid and glucose metabolism biomarkers in type 2 diabetic patients.

  2008cites this paper
• Pair feeding-mediated changes in metabolism: stress response and pathophysiology in insulin-resistant, atherosclerosis-prone JCR:LA-cp rats.

  2008cites this paper
• A survey in the United States on complementary and alternative medicine ( CAM ) use in diabetes , based on 1996 Medical Expenditure Panel

  2008influential citation
• Differences in plasma homocysteine levels between Zucker fatty and Zucker diabetic fatty rats following 3 weeks oral administration of organic vanadium compounds.

  2006cites this paper
• Comparative study on the preventing effects of oral vanadyl sulfate and dietary restriction on the age-related glucose intolerance in rats

  2005cites this paper
• Study of the hypoglycaemic activity of Lepidium sativum L. aqueous extract in normal and diabetic rats.

  2005cites this paper
• Hypoglycaemic effect of Triticum repens P. Beauv. in normal and diabetic rats.

  2005cites this paper
• The effects of peroxovanadate and peroxovanadyl on glucose metabolism in vivo and identification of signal transduction proteins involved in the mechanism of action in isolated soleus muscle

  2005cites this paper
• Insulino‐mimetic and anti‐diabetic effects of vanadium compounds

  2005cites this paper
• Effects of three and eight weeks oral administration of bis(maltolato)oxovanadium(IV) on plasma homocysteine and cysteine levels in streptozotocin-induced diabetic rats.

  2004cites this paper
• Codelivery of a tea extract prevents morbidity and mortality associated with oral vanadate therapy in streptozotocin-induced diabetic rats.

  2004cites this paper
• Oral selenate improves glucose homeostasis and partly reverses abnormal expression of liver glycolytic and gluconeogenic enzymes in diabetic rats

  2004cites this paper
• REDUÇÃO DA GLICEMIA EM RATOS DIABÉTICOS TRATADOS COM SAIS DE VANÁDIO PEROXIDADOS

  2004cites this paper
• The influence of sodium metavanadate on the process of diabetogenesis in BB rats

  2003cites this paper
• Vanadium Effects in Diabetes

  2003cites this paper
• The effect of dietary taurine supplementation on plasma and urinary free amino acid concentrations in diabetic rats.

  2003cites this paper
• Decrease of Hypothalamic Neuropeptide Y Gene Expression by Vanadyl Sulfate in Streptozotocin-Induced Diabetic Rats

  2001cites this paper
• Diazoxide effects on hypothalamic and extra-hypothalamic NPY content in Zucker rats.

  2001cites this paper
• Effect of vanadium on insulin sensitivity and appetite.

  2001cites this paper
• Treatment of diabetes with vanadium salts: general overview and amelioration of nutritionally induced diabetes in the Psammomys obesus gerbil

  2001cites this paper
• HMR390 96__100

  2001cites this paper
• Anti-diabetic and toxic effects of vanadium compounds

  2000cites this paper
• Attempt to prevent the development of diabetes in non-obese diabetic mice by oral vanadate administration.

  2000cites this paper
• Trophic effects of vanadium on beta-cells of STZ-induced insulin dependent diabetic rats & evidence for long-term relief of diabetes mellitus.

  1999cites this paper
• Distinct glucose lowering and beta cell protective effects of vanadium and food restriction in streptozotocin-diabetes.

  1999cites this paper
• Acute and chronic oral administration of bis(maltolato)oxovanadium(IV) in Zucker diabetic fatty (ZDF) rats.

  1999cites this paper
• Obesity: Autonomic circuits versus feeding

  1999cites this paper
• Vanadate treatment normalizes exaggerated vascular smooth muscle responses in the obese Zucker rat.

  1998cites this paper
• Nutritional factors that can favorably influence the glucose/insulin system: vanadium.

  1998cites this paper
• Vanadium and diabetes

  1998cites this paper
• Vanadyl Treatment Normalizes Submandibular Salivary Gland Insulin-Like Immunoreactivity in Streptozotocin-Diabetic Rats

  1998cites this paper
• Dietary xylitol supplementation prevents osteoporotic changes in streptozotocin-diabetic rats.

  1998cites this paper
• Glucose-lowering properties of vanadium compounds: comparison of coordination complexes with maltol or kojic acid as ligands.

  1997cites this paper
• Partial preservation of pancreatic β-cells by vanadian: Evidence for long-term amelioration of diabetes

  1997cites this paper
• Effects of bis(maltolato)oxovanadium(IV) are distinct from food restriction in STZ-diabetic rats.

  1997cites this paper
• Partial preservation of pancreatic beta-cells by vanadium: evidence for long-term amelioration of diabetes.

  1997cites this paper
• Effects of vanadyl sulphate on glucose homeostasis in severe diabetes induced by streptozotocin in rats.

  1997cites this paper
• Vanadyl sulphate differently influences insulin response to glucose in isolated pancreas of normal rats after in vivo or in vitro exposure.

  1996cites this paper
• Oral Antidiabetic Drugs in Research and Development

  1996cites this paper
• The serotonergic agent fluoxetine reduces neuropeptide Y levels and neuropeptide Y secretion in the hypothalamus of lean and obese rats.

  1996cites this paper
• Vanadium complexes with insulin mimic actions—A second line of protection against diabetes

  1996cites this paper
• Phlorizin or Vanadate Treatment Reverses Impaired Expression of Albumin and Hepatocyte Nuclear Factor 1 in Diabetic Rats

  1996cites this paper
• Oral Vanadyl Sulfate Improves Insulin Sensitivity in NIDDM but Not in Obese Nondiabetic Subjects

  1996cites this paper
• Differential effects of the 5-HT 1B/2C receptor agonist mCPP and the 5-HT1A agonist flesinoxan on hypothalamic neuropeptide Y in the rat: evidence that NPY may mediate serotonin's effects on food intake.

  1996cites this paper
• Increased feeding and neuropeptide Y (NPY) but not NPY mRNA levels in the hypothalamus of the rat following central administration of the serotonin synthesis inhibitor p-chlorophenylalanine.

  1996cites this paper
• Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus.

  1996cites this paper
• The role of vanadium in the management of diabetes.

  1995cites this paper
• Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies.

  1995cites this paper
• Insulin-like effects of vanadate and selenate on the expression of glucose-6-phosphate dehydrogenase and fatty acid synthase in diabetic rats.

  1995cites this paper
• Long-term correction of STZ-diabetic rats after short-term i.p. VOSO4 treatment: Persistence of insulin secreting capacities assessed by isolated pancreas studies

  1995cites this paper
• The serotonin (5-HT) antagonist methysergide increases neuropeptide Y (NPY) synthesis and secretion in the hypothalamus of the rat.

  1995cites this paper
• In vivo andin vitro studies of vanadate in human and rodent diabetes mellitus

  1995cites this paper
• Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus.

  1995cites this paper
• Toxicology of vanadium compounds in diabetic rats: The action of chelating agents on vanadium accumulation

  1995cites this paper
• Effects of vanadate on the expression of genes involved in fuel homeostasis in animal models of Type I and Type II diabetes

  1995cites this paper
• Hypoglycemic Effects of Peroxovanadium Compounds in Sprague-Dawley and Diabetic BB Rats

  1995cites this paper
• Comparison of the glucose-lowering properties of vanadyl sulfate and bis(maltolato)oxovanadium(IV) following acute and chronic administration.

  1995cites this paper
• Improved glucose tolerance by acute vanadate but not by selenate exposure in genetically obese rats (fa/fa).

  1995cites this paper
• In vivo effects of peroxovanadium compounds in BB rats

  1995cites this paper
• Section Review—Oncologic, Endocrine & Metabolic: Potential Use of Vanadium Compounds in the Treatment of Diabetes Mellitus

  1995cites this paper
• Chapter 17. Recent Advancements in the Discovery and Development of Agents for the Treatment of Diabetes.

  1995cites this paper
• Section Editor, Oncologic, Endocrine and Metabolic: Editorial Commentary

  1994cites this paper
• Relationship Between Reduction in Food Intake and Amelioration of Hyperglycemia by Oral Vanadate in STZ-Induced Diabetic Rats

  1994influential citation
• Oral Vanadium and Lowering of Blood Glucose

  1994influential citation
• Improvement in cardiac function in streptozotocin-diabetic rats by salt loading.

  1994cites this paper
• Neuropeptide Y and energy balance: one way ahead for the treatment of obesity?

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