Simulated first-phase insulin release using Humulin or insulin analog HIM2 is associated with prolonged improvement in postprandial glycemia.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  American Journal of Physiology. Endocrinology and Metabolism

• Publication date

  2005-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1152/AJPENDO.00583.2004PMID 15713685
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nonesterified fatty acids and hepatic glucose metabolism in the conscious dog.

  2004cited by this paper
• Dose-response effect of a single administration of oral hexyl-insulin monoconjugate 2 in healthy nondiabetic subjects.

  2004cited by this paper
• Oral modified insulin (HIM2) in patients with type 1 diabetes mellitus: results from a phase I/II clinical trial.

  2004cited by this paper
• Control of postprandial plasma glucose by an oral insulin product (HIM2) in patients with type 2 diabetes.

  2003cited by this paper
• Direct and indirect effects of insulin on glucose uptake and storage by the liver.

  2002cited by this paper
• Development of oral insulin: progress and current status

  2002cited by this paper
• Is reduced first-phase insulin release the earliest detectable abnormality in individuals destined to develop type 2 diabetes?

  2002cited by this paper
• FFA cause hepatic insulin resistance by inhibiting insulin suppression of glycogenolysis.

  2002cited by this paper
• Development of oral insulin: progress and current status.

  2002cited by this paper
• Physiological consequences of phasic insulin release in the normal animal.

  2002cited by this paper
• The importance of first‐phase insulin secretion: implications for the therapy of type 2 diabetes mellitus

  2001cited by this paper
• Effects of free fatty acids on gluconeogenesis and autoregulation of glucose production in type 2 diabetes.

  2001cited by this paper
• Effect of vagal cooling on the counterregulatory response to hypoglycemia induced by a low dose of insulin in the conscious dog.

  2001cited by this paper
• The head arterial glucose level is not the reference site for generation of the portal signal in conscious dogs.

  1999cited by this paper
• Effect of fast duration on disposition of an intraduodenal glucose load in the conscious dog.

  1999cited by this paper
• Biphasic insulin secretion during intravenous glucose tolerance test promotes optimal interstitial insulin profile.

  1998cited by this paper
• Hepatic glucose uptake rapidly decreases after removal of the portal signal in conscious dogs.

  1998cited by this paper
• Hepatic glucose uptake rapidly decreases after removal of the portal signal in conscious dogs

  1998cited by this paper
• The Role of Fatty Acids in Mediating the Effects of Peripheral Insulin on Hepatic Glucose Production in the Conscious Dog

  1997cited by this paper
• Comparison of the time courses of insulin and the portal signal on hepatic glucose and glycogen metabolism in the conscious dog.

  1996cited by this paper
• Intraportal glucose delivery enhances the effects of hepatic glucose load on net hepatic glucose uptake in vivo.

  1991cited by this paper
• Sources of carbon for hepatic glycogen synthesis in the conscious dog.

  1991cited by this paper
• Interaction Between Insulin and Glucose-Delivery Route in Regulation of Net Hepatic Glucose Uptake in Conscious Dogs

  1990cited by this paper
• Effect of hyperglucagonemia on hepatic glycogenolysis and gluconeogenesis after a prolonged fast.

  1990cited by this paper
• Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans.

  1989cited by this paper
• Physiological Importance of Deficiency in Early Prandial Insulin Secretion in Non-Insulin-Dependent Diabetes

  1988cited by this paper
• Insulin degradation: mechanisms, products, and significance.

  1988cited by this paper
• Importance of the route of intravenous glucose delivery to hepatic glucose balance in the conscious dog.

  1987cited by this paper
• The Relative Importance of First- and Second-Phase Insulin Secretion in Countering the Action of Glucagon on Glucose Turnover in the Conscious Dog

  1982cited by this paper
• Enzymic fluorometric continuous-flow assays for blood glucose, lactate, pyruvate, alanine, glycerol, and 3-hydroxybutyrate.

  1978cited by this paper
• Estimation of hepatic blood flow with indocyanine green.

  1962cited by this paper
• On Diabetes: Insulin Resistance Cellular Mechanisms of Insulin Resistance

  year unknowncited by this paper

• Improvement of early‐phase insulin secretion is an independent factor for achieving glycaemic control: A pooled analysis of SEED and DAWN study

  2023cites this paper
• Enterically delivered insulin tregopil exhibits rapid absorption characteristics and a pharmacodynamic effect similar to human insulin in conscious dogs

  2018influential citation
• Mechanisms of improved glucose handling after metabolic surgery: the big 6.

  2016cites this paper
• Bioengineering Strategies for the Treatment of Type I Diabetes.

  2016cites this paper
• Studies of first phase insulin secretion using imposed plasma membrane depolarization.

  2011cites this paper
• Lipeo-sCT: a novel reversible lipidized salmon calcitonin derivative, its biophysical properties and hypocalcemic activity.

  2009cites this paper
• Serum Insulin Aspart Concentrations following High-Dose Insulin Aspart Administered Directly into the Duodenum of Healthy Subjects: An Open-Labeled, Single-Blinded, and Uncontrolled Exploratory Trial

  2009cites this paper
• Influence de l'obésité sur l'insulinémie chez le chien sain

  2009cites this paper
• The effect of vagal cooling on canine hepatic glucose metabolism in the presence of hyperglycemia of peripheral origin.

  2007cites this paper
• Non-invasive routes for insulin administration: current state and perspectives

  2006cites this paper