Effect of Ammonia on Brain Serotonin Metabolism in Relation to Function in the Portacaval Shunted Rat

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Journal of Neurochemistry

• Publication date

  1990-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1471-4159.1990.tb08842.xPMID 1693945
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pathophysiology of hepatic encephalopathy.

  1990cited by this paper
• Monoamines and metabolites in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy

  1989cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
• Portacaval shunt in the rat: selective alterations in behavior and brain serotonin.

  1986cited by this paper
• [Pathogenesis and therapy of hepatic coma].

  1986cited by this paper
• Behavioral and Neurotransmitter Changes in the Urease-Infused Rat: A Model of Congenital Hyperammonemia

  1986cited by this paper
• Cerebral aminoacids in portal-systemic encephalopathy: Lack of evidence for altered γ-aminobutyric acid (GABA) function

  1986cited by this paper
• The Cortex of the Rat: A Stereotaxic Atlas

  1985cited by this paper
• Brain monoamine metabolism and behavior in portacaval-shunted rats.

  1985cited by this paper
• Relationship of brain glutamine and brain neutral amino acid concentrations after portacaval anastomosis in rats

  1985cited by this paper
• The Cortex of the Rat

  1985cited by this paper
• Developmental, Circadian and Aging Aspects of Dopamine, Norepinephrine and 5-HT in Rat Brain Regions

  1985cited by this paper
• 오이의 Ascorbic Acid Oxidase에 관한 연구

  1985cited by this paper
• Pathophysiology of hepatic encephalopathy.

  1984cited by this paper
• Region-Selective Glutamine Changes in the CNS in Relation to Function in Experimental Subacute Hepatic Encephalopathy

  1984cited by this paper
• Portacaval Anastomosis: Brain and Plasma Metabolite Abnormalities and the Effect of Nutritional Therapy

  1984cited by this paper
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  1984cited by this paper
• Amino acid changes in regions of the CNS in relation to function in experimental portal-systemic encephalopathy

  1984cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper
• Amine pathways and sleep regulation.

  1982cited by this paper
• FALSE NEUROTRANSMITTERS AND HEPATIC FAILURE

  1982cited by this paper
• Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals.

  1981cited by this paper
• Organization of ascending serotonin systems in the adult rat brain. A radioautographic study after intraventricular administration of [3H]5-hydroxytryptamine.

  1981cited by this paper
• The mechanism of hepatic coma

  1981cited by this paper
• Effect of tryptophan on sleep in the rat.

  1980cited by this paper
• Serotonin distribution in rat cerebral cortex; radioenzymatic assays with thin-layer chromatography.

  1980cited by this paper
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  1979cited by this paper
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  1978cited by this paper
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  1978cited by this paper
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  1978cited by this paper
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  1978cited by this paper
• Experimental hepatic encephalopathy. Changes of the level of wakefulness in the rat with portacaval shunt.

  1977cited by this paper
• Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts.

  1977cited by this paper
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  1976cited by this paper
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  1975cited by this paper
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  1975cited by this paper
• Tryptophan and tyrosine disposition and brain tryptophan metabolism in acute carbon tetrachloride poisoning.

  1975cited by this paper
• Hepatic encephalopathy: current status.

  1974cited by this paper
• Diagnosis of Stupor and Coma, ed 2.

  1974cited by this paper
• Etude du sommeil nocturne au cours de l'encephalopathie porto-cave

  1972cited by this paper
• [Night sleep in porto-caval encephalopathy].

  1972cited by this paper
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  1972cited by this paper
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  1971cited by this paper
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  1971cited by this paper
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  1970cited by this paper
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  1967cited by this paper
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  1963cited by this paper
• Portacaval shunt in the rat.

  1961cited by this paper
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  1954cited by this paper
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  1952cited by this paper
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  1951cited by this paper

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  2019cites this paper
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  2019cites this paper
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  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper
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  2008cites this paper
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  2008cites this paper
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  2007cites this paper
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  2007cites this paper
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  2000cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1997cites this paper
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  1996cites this paper
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  1996cites this paper
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  1996cites this paper
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  1996cites this paper
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  1995cites this paper
• Neurotransmitter alterations in congenital hyperammonemia

  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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  1994cites this paper
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  1994cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
• Recent developments in the pathophysiology and treatment of hepatic encephalopathy.

  1992cites this paper
• Neurochemical studies of hepatic encephalopathy.

  1992cites this paper
• Hepatic encephalopathy. Current concepts of the pathogenesis.

  1992cites this paper
• [3H]Paroxetine Binding and Serotonin Content of Rat Cortical Areas, Hippocampus, Neostriatum, Ventral Mesencephalic Tegmentum, and Midbrain Raphe Nuclei Region Following p‐Chlorophenylalanine and p‐Chloroamphetamine Treatment

  1992cites this paper
• Pathogenesis and treatment of portal-systemic encephalopathy: An update

  1992cites this paper
• Effect of ammonium ions on synaptic transmission in the mammalian central nervous system.

  1992cites this paper
• Animal Models of Hepatic Encephalopathies

  1992cites this paper
• Neurochemistry of hepatic encephalopathy.

  1991cites this paper
• Cerebrospinal fluid amino acids in relation to neurological status in experimental portal-systemic encephalopathy

  1991cites this paper
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  1991cites this paper
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  1991cites this paper