Increased peripheral benzodiazepine binding sites and pentraxin 3 expression in the spinal cord during EAE: relation to inflammatory cytokines and modulation by dexamethasone and rolipram.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of Neuroimmunology

• Publication date

  2000-09-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0165-5728(00)00279-4PMID 10996212
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inducible expression of the long pentraxin PTX3 in the central nervous system.

  2000cited by this paper
• Regulation of the expression of peripheral benzodiazepine receptors and their endogenous ligands during rat sciatic nerve degeneration and regeneration: a role for PBR in neurosteroidogenesis.

  1999cited by this paper
• Interferon-gamma inhibits expression of the long pentraxin PTX3 in human monocytes.

  1998cited by this paper
• Interferon‐γ inhibits expression of the long pentraxin PTX3 in human monocytes

  1998cited by this paper
• Controlled therapeutic trials of pentoxifylline in relapsing‐experimental auto‐immune encephalomyelitis

  1998cited by this paper
• New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding site

  1997cited by this paper
• Multimer Formation and Ligand Recognition by the Long Pentraxin PTX3

  1997cited by this paper
• PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis

  1997influential reference
• Pentoxifylline delays the onset of experimental allergic encephalomyelitis in mice by modulating cytokine production in peripheral blood mononuclear cells.

  1996cited by this paper
• A glucocorticoid receptor-independent mechanism for neurosteroid inhibition of tumor necrosis factor production.

  1996cited by this paper
• Cloning of mouse ptx3, a new member of the pentraxin gene family expressed at extrahepatic sites.

  1996cited by this paper
• Preventive but not therapeutic application of Rolipram ameliorates experimental autoimmune encephalomyelitis in Lewis rats.

  1996cited by this paper
• Multiple Sclerosis: A Coordinated Immunological Attack against Myelin in the Central Nervous System

  1996cited by this paper
• The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis

  1995cited by this paper
• Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat

  1995cited by this paper
• Structure and function of the pentraxins.

  1995cited by this paper
• Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes

  1994cited by this paper
• Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes.

  1994cited by this paper
• The pharmacology of neurosteroidogenesis.

  1994cited by this paper
• Peripheral benzodiazepine receptors: edited by Eva Giesen-Crouse, Academic Press, 1993. £45.00 (xiii + 281 pages) ISBN 0 1228 2630 2

  1994cited by this paper
• Pentoxifylline inhibits experimental allergic encephalomyelitis

  1993cited by this paper
• Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type 1‐ but not type 2‐associated lymphokine production, prevents induction of experimental autoimmune encephalomyelitis in Lewis rats

  1993cited by this paper
• Increase in omega 3 (peripheral type benzodiazepine) binding sites in the rat cortex and striatum after local injection of interleukin-1, tumour necrosis factor-alpha and lipopolysaccharide.

  1991cited by this paper
• IL-1 stimulates IL-6 production in endothelial cells.

  1989cited by this paper
• The role of complement in the pathogenesis of experimental allergic encephalomyelitis.

  1989cited by this paper
• Glial Fibrillary Acidic Protein Increases in the Spinal Cord of Lewis Rats with Acute Experimental Autoimmune Encephalomyelitis

  1988cited by this paper
• Human tumor necrosis factor. Production, purification, and characterization.

  1985cited by this paper
• Acute experimental autoimmune encephalomyelitis. Differences between T cell subsets in the blood and meningeal infiltrates in susceptible and resistant strains of guinea pigs.

  1983cited by this paper

• Proteomics in Multiple Sclerosis: The Perspective of the Clinician

  2022cites this paper
• Pentraxin 3: A promising therapeutic target for autoimmune diseases.

  2020cites this paper
• A Protective Role of Translocator Protein in Alzheimer's Disease Brain.

  2020cites this paper
• 12-months prospective Pentraxin-3 and metabolomic evaluation in multiple sclerosis patients treated with glatiramer acetate.

  2020cites this paper
• A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis

  2019cites this paper
• Neurosteroid Metabolites of Gonadal Steroid Hormones in Neuroprotection: Implications for Sex Differences in Neurodegenerative Disease

  2018cites this paper
• TSPO-PET Imaging to Assess Cerebral Microglial Activation in Multiple Sclerosis

  2017cites this paper
• Pentraxin‐3 is upregulated in the central nervous system during MS and EAE, but does not modulate experimental neurological disease

  2016cites this paper
• Emerging roles of the acute phase protein pentraxin-3 during central nervous system disorders.

  2016cites this paper
• The 18-kDa Mitochondrial Translocator Protein in Human Gliomas: An 11C-(R)PK11195 PET Imaging and Neuropathology Study

  2015cites this paper
• The 18-kDa Mitochondrial Translocator Protein in Human Gliomas: A 11 C-( R )PK11195 PET Imaging and Neuropathology Study

  2015cites this paper
• Impact des glucocorticoïdes circulants sur la maturation et le fonctionnement de l'inhibition spinale GABAergique

  2013cites this paper
• Translocator Protein Expression and Microglial Activation in Gliomas

  2013cites this paper
• Pentraxins in nephrology : C-reactive protein , serum amyloid P and pentraxin-3

  2013cites this paper
• Pentraxins in nephrology: C-reactive protein, serum amyloid P and pentraxin-3.

  2013cites this paper
• RNA-Seq Characterization of Spinal Cord Injury Transcriptome in Acute/Subacute Phases: A Resource for Understanding the Pathology at the Systems Level

  2013influential citation
• The Upregulation of Translocator Protein (18 kDa) Promotes Recovery from Neuropathic Pain in Rats

  2013cites this paper
• Spinal microglial activation in rat models of neuropathic and osteoarthritic pain: An autoradiographic study using [3H]PK11195

  2013cites this paper
• Effects of Anxiolytic Drugs in Animal Models of Multiple Sclerosis

  2012influential citation
• [11C]DAC-PET for Noninvasively Monitoring Neuroinflammation and Immunosuppressive Therapy Efficacy in Rat Experimental Autoimmune Encephalomyelitis Model

  2012cites this paper
• Translocator Protein (18 kDa) as a Target for Novel Anxiolytics with a Favourable Side‐Effect Profile

  2012cites this paper
• Progesterone Synthesis in the Nervous System: Implications for Myelination and Myelin Repair

  2011cites this paper
• Increased levels of serum pentraxin 3, a novel cardiovascular biomarker, in patients with inflammatory rheumatic disease

  2010cites this paper
• Variable effects of cyclophosphamide in rodent models of experimental allergic encephalomyelitis

  2010cites this paper
• Specific and Strain‐Independent Effects of Dexamethasone in the Prevention and Treatment of Experimental Autoimmune Encephalomyelitis in Rodents

  2010cites this paper
• Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

  2010cites this paper
• The translocator protein (18 kDa): central nervous system disease and drug design.

  2009cites this paper
• Phagocytes Are a Source of the Fluid-Phase Pattern Recognition Receptor PTX3: Interplay between Cellular and Humoral Innate Immunity

  2009cites this paper
• Protein expression profiles in pediatric multiple sclerosis: potential biomarkers

  2009cites this paper
• Influence of Selected Natural Products on Neutral Endopeptidase Activity and β-Amyloid Production in SK-N-SH Cells

  2008cites this paper
• Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis

  2007cites this paper
• Pentraxins in Innate Immunity: From C-Reactive Protein to the Long Pentraxin PTX3

  2007cites this paper
• The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging.

  2006cites this paper
• Role for the Peripheral Benzodiazepine Receptor in Neuroinflammation of Neurodegenerative disorders

  2006cites this paper
• The long pentraxin PTX3 in vascular pathology.

  2006cites this paper
• The antidepressant and antiinflammatory effects of rolipram in the central nervous system.

  2006cites this paper
• Microglial imaging with positron emission tomography and atrophy measurements with magnetic resonance imaging in multiple sclerosis: a correlative study

  2005cites this paper
• Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormones.

  2005cites this paper
• Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility.

  2005cites this paper
• Effect of PK11195, a peripheral benzodiazepine receptor agonist, on insulinoma cell death and insulin secretion

  2005cites this paper
• Inflammatory Pain Upregulates Spinal Inhibition via Endogenous Neurosteroid Production

  2005cites this paper
• Rolipram impairs NF-kappaB activity and MMP-9 expression in experimental autoimmune encephalomyelitis.

  2005cites this paper
• [The neuroprotective properties of sex steroids and neurosteroids].

  2004cites this paper
• Membrane and soluble pattern recognition receptors: the unique functions of the long pentraxin PTX3

  2004cites this paper
• Sex hormones and brain aging.

  2004cites this paper
• Differential Expression of Pentraxin 3 in Fibroblasts from Patients with Major Depression

  2004cites this paper
• Propiedades neuroprotectoras de los esteroides sexuales y los neuroesteroides

  2004cites this paper
• Pentraxin 3, a non-redundant soluble pattern recognition receptor involved in innate immunity.

  2003cites this paper
• The peripheral benzodiazepine receptor ligand PK11195 binds with high affinity to the acute phase reactant alpha1-acid glycoprotein: implications for the use of the ligand as a CNS inflammatory marker.

  2003cites this paper
• Functional neuroinflammatory- and serotonergic imaging in Alzheimer's disease: validation and preliminary clinical findings

  2003influential citation
• Erythropoietin Selectively Attenuates Cytokine Production and Inflammation in Cerebral Ischemia by Targeting Neuronal Apoptosis

  2003cites this paper
• Upregulation of mitochondrial peripheral benzodiazepine receptor expression by cytokine‐induced damage of human pancreatic islets

  2002cites this paper
• Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis.

  2002cites this paper
• PTX3 in small-vessel vasculitides: an independent indicator of disease activity produced at sites of inflammation.

  2001cites this paper
• Identification of Genes Induced in Peripheral Nerve after Injury

  2001cites this paper