Glycogen synthase kinase-3 regulates cigarette smoke extract- and IL-1β-induced cytokine secretion by airway smooth muscle.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  American Journal of Physiology - Lung cellular and Molecular Physiology

• Publication date

  2011-06-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1152/ajplung.00232.2010PMID 21421749
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle

  2010cited by this paper
• {beta}-Catenin regulates airway smooth muscle contraction.

  2010cited by this paper
• catenin Regulates Airway Smooth Muscle Contraction

  2010cited by this paper
• Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype

  2010cited by this paper
• alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases.

  2009cited by this paper
• Muscarinic M3 receptor stimulation increases cigarette smoke-induced IL-8 secretion by human airway smooth muscle cells

  2009influential reference
• Cigarette Smoke, Inflammation, and Lung Injury: A Mechanistic Perspective

  2009cited by this paper
• Airway smooth muscle hyperplasia and hypertrophy correlate with glycogen synthase kinase-3(beta) phosphorylation in a mouse model of asthma.

  2009cited by this paper
• Angiogenesis: a potentially critical part of remodelling in chronic airway diseases?

  2008influential reference
• Shared principles in NF-kappaB signaling.

  2008cited by this paper
• Inhibition of Glycogen Synthase Kinase-3β Is Sufficient for Airway Smooth Muscle Hypertrophy*

  2008cited by this paper
• Hepatocyte growth factor regulates cyclooxygenase-2 expression via beta-catenin, Akt, and p42/p44 MAPK in human bronchial epithelial cells.

  2008cited by this paper
• Novel regulation of vascular endothelial growth factor-A (VEGF-A) by transforming growth factor (beta)1: requirement for Smads, (beta)-CATENIN, AND GSK3(beta).

  2008cited by this paper
• Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease

  2008cited by this paper
• GSK-3/beta-catenin signaling axis in airway smooth muscle: role in mitogenic signaling.

  2008cited by this paper
• Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.

  2007cited by this paper
• Cooperative regulation of GSK-3 by muscarinic and PDGF receptors is associated with airway myocyte proliferation.

  2007cited by this paper
• Vascular endothelial growth factor: an angiogenic factor reflecting airway inflammation in healthy smokers and in patients with bronchitis type of chronic obstructive pulmonary disease?

  2007cited by this paper
• GLYCOGEN SYNTHASE KINASE 3&bgr; AS A TARGET FOR THE THERAPY OF SHOCK AND INFLAMMATION

  2007influential reference
• Inhibition of tumor necrosis factor-alpha-inducible inflammatory genes by interferon-gamma is associated with altered nuclear factor-kappaB transactivation and enhanced histone deacetylase activity.

  2007cited by this paper
• Glycogen Synthase Kinase-3 (GSK3): Inflammation, Diseases, and Therapeutics

  2007cited by this paper
• The selectivity of protein kinase inhibitors: a further update.

  2007cited by this paper
• Glycogen synthase kinase-3beta inhibition attenuates asthma in mice.

  2007cited by this paper
• Eosinophilic airway inflammation in COPD

  2006influential reference
• Regulatory features of interleukin-1beta-mediated prostaglandin E2 synthesis in airway smooth muscle.

  2006cited by this paper
• Inhibition of Tumor Necrosis Factor-α-Inducible Inflammatory Genes by Interferon-γ Is Associated with Altered Nuclear Factor-κB Transactivation and Enhanced Histone Deacetylase Activity

  2006cited by this paper
• Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase‐3β

  2006cited by this paper
• Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle.

  2006cited by this paper
• Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse.

  2006cited by this paper
• Wnt/beta-catenin signaling in development and disease.

  2006cited by this paper
• VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-κB signaling pathway

  2006cited by this paper
• Airway smooth muscle: a modulator of airway remodeling in asthma.

  2005cited by this paper
• Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells.

  2005influential reference
• The role of airway smooth muscle in the pathogenesis of airway wall remodeling in chronic obstructive pulmonary disease.

  2005cited by this paper
• Cigarette smoke induces IL-8, but inhibits eotaxin and RANTES release from airway smooth muscle

  2005influential reference
• Glycogen-Synthase Kinase3beta/beta-catenin axis promotes angiogenesis through activation of vascular endothelial growth factor signaling in endothelial cells.

  2005cited by this paper
• Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription.

  2005cited by this paper
• Wnt/β-Catenin Signaling Induces Proliferation, Survival and Interleukin-8 in Human Endothelial Cells

  2005cited by this paper
• Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells.

  2005cited by this paper
• Glycogen Synthase Kinase-3β Participates in Nuclear Factor κB–Mediated Gene Transcription and Cell Survival in Pancreatic Cancer Cells

  2005cited by this paper
• Glycogen-Synthase Kinase3β/β-Catenin Axis Promotes Angiogenesis Through Activation of Vascular Endothelial Growth Factor Signaling in Endothelial Cells

  2005cited by this paper
• Toll-like receptor–mediated cytokine production is differentially regulated by glycogen synthase kinase 3

  2005cited by this paper
• Genetic Deletion of Glycogen Synthase Kinase-3β Abrogates Activation of IκBα Kinase, JNK, Akt, and p44/p42 MAPK but Potentiates Apoptosis Induced by Tumor Necrosis Factor*

  2004cited by this paper
• Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor.

  2004cited by this paper
• Synthetic responses in airway smooth muscle.

  2004cited by this paper
• Crossregulation of NF‐κB by the APC/GSK‐3β/β‐catenin pathway

  2004cited by this paper
• Possible effects of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease.

  2003cited by this paper
• Chronic obstructive pulmonary disease: molecular and cellularmechanisms

  2003cited by this paper
• Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo.

  2003cited by this paper
• GSK-3: tricks of the trade for a multi-tasking kinase

  2003cited by this paper
• Eotaxin and CCR3 are up‐regulated in exacerbations of chronic bronchitis

  2002cited by this paper
• Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes.

  2002cited by this paper
• Role of glycogen synthase kinase-3 in TNF-α-induced NF-κB activation and apoptosis in hepatocytes

  2002cited by this paper
• Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development.

  2002cited by this paper
• Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: National Heart, Lung, and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD): executive summary.

  2001influential reference
• Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia.

  2001cited by this paper
• Complex Formation of Adenomatous Polyposis Coli Gene Product and Axin Facilitates Glycogen Synthase Kinase-3β-dependent Phosphorylation of β-Catenin and Down-regulates β-Catenin*

  2000cited by this paper
• Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation.

  2000influential reference
• Airway smooth muscle cells: contributing to and regulating airway mucosal inflammation?

  2000cited by this paper
• Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation

  2000cited by this paper
• Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription.

  2000cited by this paper
• Induction of eotaxin expression and release from human airway smooth muscle cells by IL-1beta and TNFalpha: effects of IL-10 and corticosteroids.

  1999cited by this paper
• Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells.

  1999cited by this paper
• Induction of eotaxin expression and release from human airway smooth muscle cells by IL‐1β and TNFα: effects of IL‐10 and corticosteroids

  1999cited by this paper
• Bradykinin stimulates IL-8 production in cultured human airway smooth muscle cells: role of cyclooxygenase products.

  1998cited by this paper
• Severity of airflow limitation is associated with severity of airway inflammation in smokers.

  1998cited by this paper
• Glycogen Synthase Kinase 3 (cid:2) Functions To Specify Gene-Specific, NF- (cid:3) B-Dependent Transcription

  year unknowncited by this paper

• Design, Synthesis, Biological Evaluation and Molecular Docking Studies of a New Series of Maleimide Derivatives

  2024cites this paper
• DKK1 Positively Correlates with Lung Function in COPD Patients and Reduces Airway Inflammation

  2022cites this paper
• Cigarette smoke-induced toxicity consequences of intracellular iron dysregulation and ferroptosis.

  2021cites this paper
• Design, synthesis, in vitro antiproliferative evaluation and GSK-3β kinase inhibition of a new series of pyrimidin-4-one based amide conjugates.

  2021cites this paper
• Perspectives on Wnt Signal Pathway in the Pathogenesis and Therapeutics of Chronic Obstructive Pulmonary Disease

  2019cites this paper
• Acute and Recovery Changes of TNF-α and IL-1β in Response to Aerobic Exercise in Smokers and Non-smokers

  2018cites this paper
• Revisiting asthma therapeutics: focus on WNT signal transduction.

  2018cites this paper
• β-Catenin Directs Nuclear Factor-κB p65 Output via CREB-Binding Protein/p300 in Human Airway Smooth Muscle

  2017cites this paper
• Developmental and pathological roles of BMP/follistatin-like 1 in the lung

  2017cites this paper
• University of Groningen β-Catenin Directs Nuclear Factor-κB p 65 Output via CREB-Binding Protein / p 300 in Human Airway Smooth Muscle

  2017cites this paper
• WNT and β-catenin signalling in airway smooth muscle: emerging concepts for asthma

  2017cites this paper
• Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways

  2017cites this paper
• A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis

  2016cites this paper
• Upregulation of TRPM7 augments cell proliferation and interleukin-8 release in airway smooth muscle cells of rats exposed to cigarette smoke

  2016cites this paper
• The ADP Antagonist MRS2179 Regulates the Phenotype of Smooth Muscle Cells to Limit Intimal Hyperplasia

  2015cites this paper
• Regulation of pulmonary inflammation by mesenchymal cells.

  2014cites this paper
• β-catenin as a regulator and therapeutic target for asthmatic airway remodeling

  2014cites this paper
• GSK3β Is Increased in Adipose Tissue and Skeletal Muscle from Women with Gestational Diabetes Where It Regulates the Inflammatory Response

  2014cites this paper
• TGF-β-Activated Kinase 1 (TAK1) Signaling Regulates TGF-β-Induced WNT-5A Expression in Airway Smooth Muscle Cells via Sp1 and β-Catenin

  2014cites this paper
• Airway Smooth Muscle Malfunction in COPD

  2014cites this paper
• Cardiac-Specific Overexpression of Metallothionein Rescues against Cigarette Smoking Exposure-Induced Myocardial Contractile and Mitochondrial Damage

  2013cites this paper
• Glycogen synthase kinase‐3 (GSK‐3) regulates TGF‐β1‐induced differentiation of pulmonary fibroblasts

  2013influential citation
• Targeting the Metabolic Syndrome and Type 2 Diabetes by Preventing Inflammation

  2012cites this paper
• Regulation by Glycogen Synthase Kinase-3 of Inflammation and T Cells in CNS Diseases

  2011cites this paper