A functional gamma gene formed from known gamma-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes.

No abstract is available for this paper.

• Publication year

  1986

• Venue

  Nature

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 3487735
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Limited diversity of the rearranged T-cell gamma gene.

  1985cited by this paper
• Developmental regulation of T-cell receptor gene expression

  1985cited by this paper
• Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors.

  1985cited by this paper
• Structure, organization, and somatic rearrangement of T cell gamma genes.

  1985cited by this paper
• Lambda chains and genes in inbred mice.

  1985cited by this paper
• Expression of the T-cell-specific γ gene is unnecessary in T cells recognizing class II MHC determinants

  1985cited by this paper
• Expression of T-cell antigen receptor genes during fetal development in the thymus

  1985cited by this paper
• Molecular cloning of a cDNA encoding human antihaemophilic factor

  1984cited by this paper
• Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

  1984cited by this paper
• Somatic recombination in a murine T-cell receptor gene

  1984cited by this paper
• Inhibition of cytotoxic T lymphocyte activity by concanavalin A.

  1982cited by this paper
• Physical linkage of the constant region genes for immunoglobulins lambda I and lambda III.

  1981cited by this paper
• Differences between germ-line and rearranged immunoglobulin Vκ coding sequences suggest a localized mutation mechanism

  1981cited by this paper
• Organization of four mouse lambda light chain immunoglobulin genes.

  1981cited by this paper
• Sequencing end-labeled DNA with base-specific chemical cleavages.

  1980cited by this paper
• Detection of specific sequences among DNA fragments separated by gel electrophoresis.

  1975cited by this paper

• Evolution and function of the TCR Vgamma9 chain repertoire: It's good to be public.

  2015cites this paper
• T-cell receptor gene rearrangement in primary tumors: effect of genetic background and inducing agent

  2004cites this paper
• Rearrangement patterns of T-cell receptor genes in the spleen of athymic (nu/nu) young mice

  2004cites this paper
• The role of gammadelta T cells in the airways.

  2000cites this paper
• Role of gamma delta T lymphocytes in immune response in humans and mice.

  1998cites this paper
• Contribution of extrathymic γδ T cells to the expression of heat‐shock protein and to protective immunity in mice infected with Toxoplasma gondii

  1996cites this paper
• Positive Selection of γδ CTL by TL Antigen Expressed in the Thymus

  1996cites this paper
• Alpha beta and gamma delta T cells can share a late common precursor.

  1995cites this paper
• Commitment and maintenance of the alpha beta and gamma delta T cell lineages.

  1995cites this paper
• Tolerance and self-reactivity in V gamma 1.1C gamma 4 transgenic mice.

  1994cites this paper
• The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1987. Somatic generation of immune diversity.

  1993cites this paper
• Gamma delta T cell receptor repertoire in brain lesions of patients with multiple sclerosis.

  1993cites this paper
• Nucleotide deletion of T cell receptor V gamma 2 and J gamma 2 coding sequences at V gamma 2-J gamma 2 junctions in immature B cell lines.

  1992cites this paper
• Neoplastic epithelial cells express alpha-subunit of muscle nicotinic acetylcholine receptor in thymomas from patients with myasthenia gravis.

  1991cites this paper
• Rearrangement and junctional-site sequence analyses of T-cell receptor gamma genes in intestinal intraepithelial lymphocytes from murine athymic chimeras

  1991cites this paper
• Control of gamma delta T-cell development.

  1991cites this paper
• Biology of the human gamma delta T-cell receptor.

  1991cites this paper
• Self‐Reactive γδ T Lymphocytes: Implications for T‐Cell Ontogeny and Reactivity

  1991cites this paper
• Biology of the Human γ T‐Cell Receptor

  1991cites this paper
• T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells.

  1990cites this paper
• Characterization of gamma/delta T cell clones isolated from human fetal liver and thymus.

  1990cites this paper
• Activation of the immune system in the testis.

  1990cites this paper
• Developmentally regulated fetal thymic and extrathymic T-cell receptor gamma delta gene expression.

  1990cites this paper
• Development of human T lymphocytes and their thymus-dependency.

  1990cites this paper
• Ontogeny of T-cell precursors: a model for the initial stages of human T-cell development.

  1989cites this paper
• Perforin mRNA in primary peritoneal exudate cytotoxic T lymphocytes.

  1989cites this paper
• The structure, function, and molecular genetics of the gamma/delta T cell receptor.

  1989cites this paper
• TCR gamma delta cells--minor redundant T cell subset or specialized immune system component?

  1989cites this paper
• T cell function and expression are dramatically altered in T cell receptor V gamma 1.1J gamma 4C gamma 4 transgenic mice.

  1989cites this paper
• T-cell receptor delta-chain diversity in peripheral lymphocytes.

  1989cites this paper
• Developmental biology of T cell receptors.

  1989cites this paper
• Blockage of alpha beta T-cell development by TCR gamma delta transgenes.

  1989cites this paper
• Nobel lecture in physiology or medicine--1987. Somatic generation of immune diversity.

  1988cites this paper
• Analysis of expression of CD2, CD3, and T cell antigen receptor molecules during early human fetal thymic development.

  1988cites this paper
• "Radioresistant" intrathymic T cell precursors express T cell receptor C gamma 4- and C delta-specific gene messages.

  1988cites this paper
• Characterization of a murine T cell surface disulfide-linked dimer of 45-kDa glycopeptides (YE1/48 antigen). Comparison with T cell receptor, purification, and partial amino acid sequences.

  1988cites this paper
• Regulation of expression of T cell γ chain, L3T4 and Ly‐2 messages in Abelson/moloney virus‐transformed T cell lines

  1988cites this paper
• Molecular genetics and the diagnosis of lymphoma.

  1988cites this paper
• Predominant variable region gene usage by gamma/delta T cell receptor- bearing cells in the adult thymus

  1988cites this paper
• Somatic generation of immune diversity

  1988cites this paper
• Molecular analysis of T cell receptor gamma gene expression in allo‐activated splenic T cells of adult mice

  1988cites this paper
• Antibody and T-cell receptors.

  1988cites this paper
• Trans-acting regulatory factors for T cell antigen receptor alpha- and gamma-chain gene expression.

  1988cites this paper
• Surface expression of only gamma delta and/or alpha beta T cell receptor heterodimers by cells with four (alpha, beta, gamma, delta) functional receptor chains

  1988cites this paper
• Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes

  1988cites this paper
• Identification of a second T-cell antigen receptor in human and mouse by an anti-peptide gamma-chain-specific monoclonal antibody.

  1987cites this paper
• T cell gamma receptor

  1987cites this paper
• T lymphocyte surface molecules: structure and function.

  1987cites this paper
• The unfolding story of T cell receptor γ

  1987cites this paper
• Characterization of Lyt-2-, L3T4- class I-specific cytolytic clones in C3H-gld/gld mice. Implications for functions of accessory molecules and programmed development

  1987cites this paper
• Structure, function, and serology of the T-cell antigen receptor complex.

  1987cites this paper
• T cell rearranging gene gamma: diversity and mRNA expression in fresh cells from T cell acute lymphoblastic leukemia.

  1987cites this paper
• The gamma T-cell antigen receptor

  1987cites this paper
• Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T lymphocytes.

  1987cites this paper
• The T-cell antigen receptor gamma gene: rearrangement and cell lineages.

  1987cites this paper
• Abnormal expression of T cell receptor genes in Lyt-2- L3T4- lymphocytes of lpr mice: comparison with normal immature thymocytes.

  1987cites this paper
• Expression of the T-cell receptor gamma-chain gene products on the surface of peripheral T cells and T-cell blasts generated by allogeneic mixed lymphocyte reaction.

  1987cites this paper
• A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

  1987cites this paper
• T-cell receptors of human suppressor cells

  1987cites this paper
• Genes of the T-cell antigen receptor in normal and malignant T cells.

  1987cites this paper
• T-cell gamma gene is allelically but not isotypically excluded and is not required in known functional T-cell subsets.

  1987cites this paper
• Biophysical aspects of antigen recognition by T cells.

  1987cites this paper
• Two types of gamma T cell receptors expressed by T cell acute lymphoblastic leukemias

  1987cites this paper
• T gamma protein is expressed on murine fetal thymocytes as a disulphide-linked heterodimer.

  1987cites this paper
• Repertoire of the human T cell gamma genes: high frequency of nonfunctional transcripts in thymus and mature T cells

  1987cites this paper
• Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules

  1987cites this paper
• Human T cell gamma chain joining regions and T cell development.

  1987cites this paper
• Athymic mice express a high level of functional gamma-chain but greatly reduced levels of alpha- and beta-chain T-cell receptor messages.

  1986cites this paper
• Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

  1986cites this paper
• Why affinity progression of antibodies during immune responses is probably not accompanied by parallel changes in the immunoglobulin-like antigen-specific receptors on T cells.

  1986cites this paper
• A phosphorylated, disulfide-linked membrane protein in murine cytotoxic T lymphocytes.

  1986cites this paper
• Transcripts of functionally rearranged gamma genes in primary T cells of adult immunocompetent mice

  1986cites this paper
• Serine esterase in cytolytic T lymphocytes

  1986cites this paper