Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Genes, Chromosomes and Cancer

• Publication date

  2003-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/gcc.10149PMID 12508240
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• High level amplification of N-MYC is not associated with adverse histology or outcome in primary retinoblastoma tumours

  2002cited by this paper
• Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN.

  2002influential reference
• Felix Mitelman: Database of chromosome aberrations in cancer

  2002cited by this paper
• Marked differences in unilateral isolated retinoblastomas from young and older children studied by comparative genomic hybridization

  2001influential reference
• Minimal regions of chromosomal imbalance in retinoblastoma detected by comparative genomic hybridization.

  2001influential reference
• Clinical importance of cytogenetics in acute myeloid leukaemia.

  2001cited by this paper
• Second primary tumors in hereditary retinoblastoma: a register-based study, 1945-1997: is there an age effect on radiation-related risk?

  2001cited by this paper
• Prognostic factors for hematologic cancers.

  2000cited by this paper
• Clinical implications of recurring chromosomal and associated molecular abnormalities in acute lymphoblastic leukemia.

  2000cited by this paper
• Presence of human papilloma virus in tumor tissue from children with retinoblastoma: an alternative mechanism for tumor development.

  2000cited by this paper
• Prognostic value of cytogenetic findings in adults with acute myeloid leukemia.

  2000cited by this paper
• Detection of chromosome imbalances in retinoblastoma by parallel karyotype and CGH analyses

  2000cited by this paper
• Fluorescence in situ hybridization techniques for the rapid detection of genetic prognostic factors in neuroblastoma

  2000cited by this paper
• Proliferation not apoptosis as a prognostic indicator in retinoblastoma

  1999cited by this paper
• Developmental basis of retinal-specific induction of cancer by RB mutation.

  1999cited by this paper
• The retinoblastoma gene family: cousins with overlapping interests.

  1998cited by this paper
• Overview of RB gene mutations in patients with retinoblastoma. Implications for clinical genetic screening.

  1998cited by this paper
• Cytogenetic findings in 73 osteosarcoma specimens and a review of the literature.

  1997cited by this paper
• Histopathologic risk factors in retinoblastoma: A retrospective study of 172 patients treated in a single institution

  1996cited by this paper
• Chromosome evolution in retinoblastoma.

  1995cited by this paper
• Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas

  1995cited by this paper
• Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors

  1994cited by this paper
• Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

  1992cited by this paper
• Retinoblastoma in transgenic mice

  1990cited by this paper
• Incidence of second neoplasms in patients with bilateral retinoblastoma.

  1988cited by this paper
• Human Cytogenetics. A Practical Approach

  1987cited by this paper
• Human retinoblastoma susceptibility gene: cloning, identification, and sequence

  1987cited by this paper
• Structural evidence for the authenticity of the human retinoblastoma gene.

  1987cited by this paper
• A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

  1986cited by this paper
• Second primary neoplasms in patients with retinoblastoma.

  1986cited by this paper
• Molecular and cytologic analysis of DNA amplification in retinoblastoma.

  1985cited by this paper
• Nonrandom chromosomal changes in untreated retinoblastomas.

  1983cited by this paper
• Genetics and the Etiology of Childhood Cancer

  1976cited by this paper
• Mutation and cancer: statistical study of retinoblastoma.

  1971cited by this paper

• Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic Analysis.

  2021cites this paper
• Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma

  2021cites this paper
• Molecular Changes in Retinoblastoma beyond RB1: Findings from Next-Generation Sequencing

  2021cites this paper
• Recurrent Somatic Chromosomal Abnormalities in Relapsed Extraocular Retinoblastoma

  2021cites this paper
• Whole-Genome Sequencing of Retinoblastoma Reveals the Diversity of Rearrangements Disrupting RB1 and Uncovers a Treatment-Related Mutational Signature

  2021cites this paper
• MYCN amplification levels in primary retinoblastoma tumors analyzed by Multiple Ligation-dependent Probe Amplification

  2021cites this paper
• Retinoblastoma Genetics

  2020cites this paper
• Retinoblastoma: Etiology, Modeling, and Treatment

  2020cites this paper
• Retinoblastoma Tumorigenesis

  2019cites this paper
• Genetics and Epigenetics

  2019cites this paper
• Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations

  2019cites this paper
• miRNome landscape analysis reveals a 30 miRNA core in retinoblastoma

  2017cites this paper
• [Value of serum miR-17-92 cluster in diagnosis of retinoblastoma].

  2017cites this paper
• Genomic landscape of retinoblastoma in Rb−/−p130−/− mice resembles human retinoblastoma

  2017cites this paper
• Applied bioinformatics: Genomics of human and murine retinoblastoma

  2017cites this paper
• Somatic genomic alterations in retinoblastoma beyond RB1 are rare and limited to copy number changes

  2016cites this paper
• Genomic and transcriptomic profiling of resistant CEM/ADR-5000 and sensitive CCRF-CEM leukaemia cells for unravelling the full complexity of multi-factorial multidrug resistance

  2016cites this paper
• A Meta-Analysis of Retinoblastoma Copy Numbers Refines the List of Possible Driver Genes Involved in Tumor Progression

  2016cites this paper
• Overview of recurrent chromosomal losses in retinoblastoma detected by low coverage next generation sequencing.

  2016cites this paper
• Genetics and epigenetics of human retinoblastoma.

  2015cites this paper
• Loss of photoreceptorness and gain of genomic alterations in retinoblastoma reveal tumor progression

  2015cites this paper
• RB1 gene inactivation by chromothripsis in human retinoblastoma

  2014cites this paper
• Large germline copy number variations as predisposing factor in childhood neoplasms.

  2014cites this paper
• High resolution SNP array profiling identifies variability in retinoblastoma genome stability

  2014cites this paper
• MiR-101, downregulated in retinoblastoma, functions as a tumor suppressor in human retinoblastoma cells by targeting EZH2.

  2014cites this paper
• Retinoblastoma and the RB1 Cancer Syndrome

  2013cites this paper
• Inhibition of polo-like kinase 1 promotes hyperthermia sensitivity via inactivation of heat shock transcription factor 1 in human retinoblastoma cells.

  2013cites this paper
• Etude des relations génotype/phénotype dans le rétinoblastome

  2012cites this paper
• Oncogenic microRNA 17-92 cluster is regulated by epithelial cell adhesion molecule and could be a potential therapeutic target in retinoblastoma

  2012cites this paper
• Microarray gene-expression analysis in ocular oncology: uveal melanoma and retinoblastoma

  2011cites this paper
• Clinicopathologic significances of nuclear expression of nuclear factor-κB transcription factors in retinoblastoma

  2011cites this paper
• Overexpression of DNA methyltransferases 1, 3a, and 3b significantly correlates with retinoblastoma tumorigenesis.

  2010cites this paper
• Genetics of retinoblastoma

  2010cites this paper
• GENOMIC CHARACTERIZATION OF RECURRENT CHROMOSOMAL ABERRATIONS IN RETINOBLASTOMA

  2010cites this paper
• Cdh11 Acts as a Tumor Suppressor in a Murine Retinoblastoma Model by Facilitating Tumor Cell Death

  2010cites this paper
• A Subset of Retinoblastoma Lacking RB1 Gene Mutations have High-level MYCN Gene Amplification

  2010cites this paper
• Tumors of the eye

  2010cites this paper
• Array comparative genomic hybridization in retinoma and retinoblastoma tissues

  2009cites this paper
• Pediatric Molecular Pathology

  2009cites this paper
• Allelic imbalance at 13q31 is associated with reduced GPC6 in Chinese with sporadic retinoblastoma

  2009cites this paper
• PI3K/Akt pathway mutations in retinoblastoma.

  2009cites this paper
• Role of the tumor suppressor ARF and the p 53-pathway in retinoblastoma development

  2009cites this paper
• High incidence of allelic loss at 16q12.2 region spanning RB2/p130 gene in retinoblastoma

  2009cites this paper
• MOLECULAR KARYOTYPE OF SPORADIC UNILATERAL RETINOBLASTOMA TUMORS

  2009cites this paper
• KIF14 and E2F3 mRNA expression in human retinoblastoma and its phenotype association

  2009cites this paper
• Retinoblastoma in Great Britain 1963–2002

  2008cites this paper
• Retinoblastoma: From Disease to Discovery

  2008cites this paper
• Genomic differences between retinoma and retinoblastoma

  2008cites this paper
• Array comparative genomic hybridization analysis of olfactory neuroblastoma

  2008cites this paper
• Insights from mouse models into human retinoblastoma

  2008cites this paper
• Genetic Progression from Retina to Retinoblastoma

  2008cites this paper
• Hypermethylation of CpG island loci of multiple tumor suppressor genes in retinoblastoma.

  2008cites this paper
• CONSTITUTIVE AND SOMATIC GENETIC EVENTS IN RETINOMA AND RETINOBLASTOMA

  2008cites this paper
• Novel 6p rearrangements and recurrent translocation breakpoints in retinoblastoma cell lines identified by spectral karyotyping and mBAND analyses.

  2007cites this paper
• Murine bilateral retinoblastoma exhibiting rapid‐onset, metastatic progression and N‐myc gene amplification

  2007cites this paper
• Phyllodes tumors of the breast segregate in two groups according to genetic criteria

  2007cites this paper
• One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma

  2007influential citation
• Profiling genomic copy number changes in retinoblastoma beyond loss of RB1

  2007influential citation
• High expression of KIF14 in retinoblastoma: association with older age at diagnosis.

  2007cites this paper
• Evaluation of Whole Genome Amplification Protocols for Array and Oligonucleotide CGH

  2007cites this paper
• What can we learn from the population incidence of cancer? Armitage and Doll revisited.

  2007cites this paper
• Expression analysis of 6p22 genomic gain in retinoblastoma

  2006cites this paper
• Chromosome 6p amplification and cancer progression

  2006cites this paper
• Chromosome 6 p amplification and cancer progression Gda

  2006cites this paper
• Insights from animal models on the origins and progression of retinoblastoma.

  2006cites this paper
• Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene.

  2006cites this paper
• Overexpression of genes on 16q associated with cisplatin resistance of testicular germ cell tumor cell lines.

  2006cites this paper
• Role of the retinoblastoma tumor suppressor in the maintenance of genome integrity.

  2006cites this paper
• Genomic gains on chromosome 1q in retinoblastoma: Consequences on gene expression and association with clinical manifestation

  2005cites this paper
• [Genomic retinoblastoma perspectives: implications of tumor supressor gene RB1].

  2005cites this paper
• Perspectivas en la genómica del retinoblastoma: Implicaciones del gen supresor de tumor RB1

  2005cites this paper
• Detection of chromosomal abnormalities by comparative genomic hybridization

  2005cites this paper
• Overexpression of genes on 16q associated with cisplatin resistance of testicular germ cell tumor cell lines

  2005cites this paper
• Biology and therapy of malignant solid tumors in childhood.

  2005cites this paper
• Detection of chromosomal imbalances in retinoblastoma by matrix‐based comparative genomic hybridization

  2005cites this paper
• The search for the retinoblastoma cell of origin

  2005cites this paper
• The RB Protein Family in Retinal Development and Retinoblastoma: New Insights from New Mouse Models

  2005cites this paper
• Molecular studies of loss of heterozygosity in Chinese sporadic retinoblastoma patients.

  2005cites this paper
• Genetic analyses of the Rb and p53 genes in murine development and tumorigenesis

  2005cites this paper
• Cell type-specific effects of Rb deletion in the murine retina.

  2004cites this paper
• Minimal 16q genomic loss implicates cadherin-11 in retinoblastoma.

  2004cites this paper
• Chromosomal aberrations in Korean nonsmall cell lung carcinomas: degenerate oligonucleotide primed polymerase chain reaction comparative genomic hybridization studies.

  2004cites this paper
• Tumeurs de la rétine

  2004cites this paper
• Biology and therapy of malignant solid tumors in childhood.

  2002cites this paper
• 4 Comparative genomic hybridization

  2002cites this paper