Involvement of phospholipases D1 and D2 in sphingosine 1-phosphate-induced ERK (extracellular-signal-regulated kinase) activation and interleukin-8 secretion in human bronchial epithelial cells.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Biochemical Journal

• Publication date

  2002-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1042/BJ20020586PMID 12149127PMCID PMC1222936
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phospholipase D Activation by Sphingosine 1-Phosphate Regulates Interleukin-8 Secretion in Human Bronchial Epithelial Cells*

  2002cited by this paper
• Dimerization of phospholipase d isozymes.

  2002cited by this paper
• Involvement of Endothelial Nitric Oxide in Sphingosine‐1‐Phosphate‐Induced Angiogenesis

  2002cited by this paper
• Involvement of Phospholipase D in Sphingosine 1-Phosphate-induced Activation of Phosphatidylinositol 3-Kinase and Akt in Chinese Hamster Ovary Cells Overexpressing EDG3*

  2001cited by this paper
• Lysophospholipids--Receptor Revelations

  2001cited by this paper
• Enhancement of lysophosphatidic acid-induced ERK phosphorylation by phospholipase D1 via the formation of phosphatidic acid.

  2001cited by this paper
• Lysophospholipids increase interleukin-8 expression in ovarian cancer cells.

  2001cited by this paper
• Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator.

  2001cited by this paper
• Was the evolution of plastid genetic machinery discontinuous?

  2001cited by this paper
• Role for Phospholipase D in Receptor-Mediated Endocytosis

  2001cited by this paper
• Sphingosine 1‐phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma

  2001cited by this paper
• Lysophospholipid receptors.

  2001cited by this paper
• Sphingosine‐1‐phosphate induces proliferation of astrocytes: regulation by intracellular signalling cascades

  2001cited by this paper
• Sphingosine 1-phosphate signalling in mammalian cells.

  2000cited by this paper
• Sphingosine 1-phosphate induces arachidonic acid mobilization in A549 human lung adenocarcinoma cells.

  2000cited by this paper
• Ras/mitogen-activated protein kinase mediates norepinephrine-induced phospholipase D activation in rabbit aortic smooth muscle cells by a phosphorylation-dependent mechanism.

  2000cited by this paper
• Sphingosine 1-phosphate stimulates tyrosine phosphorylation of focal adhesion kinase and chemotactic motility of endothelial cells via the G(i) protein-linked phospholipase C pathway.

  2000cited by this paper
• The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras*

  2000cited by this paper
• Sphingosine 1‐Phosphate Activates Erk‐1/‐2 by Transactivating Epidermal Growth Factor Receptor in Rat‐2 Cells

  2000cited by this paper
• Differential roles of Edg-1 and Edg-5, sphingosine 1-phosphate receptors, in the signaling pathways in C6 glioma cells.

  2000cited by this paper
• Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3.

  2000cited by this paper
• Sphingosine 1-Phosphate-induced Cell Proliferation, Survival, and Related Signaling Events Mediated by G Protein-coupled Receptors Edg3 and Edg5*

  2000cited by this paper
• Sphingosine 1-phosphate signalling in mammalian cells

  2000cited by this paper
• Sphingosine-1-phosphate activates phospholipase D in human airway epithelial cells via a G protein-coupled receptor.

  2000cited by this paper
• Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors.

  2000cited by this paper
• Receptor‐mediated activation of phospholipase D by sphingosine 1‐phosphate in skeletal muscle C2C12 cells

  1999cited by this paper
• Regulation of Interleukin-8 Gene Expression

  1999cited by this paper
• Transduction of intracellular calcium signals through G protein-mediated activation of phospholipase C by recombinant sphingosine 1-phosphate receptors.

  1999cited by this paper
• Phospholipase D and Its Product, Phosphatidic Acid, Mediate Agonist-dependent Raf-1 Translocation to the Plasma Membrane and the Activation of the Mitogen-activated Protein Kinase Pathway*

  1999cited by this paper
• Sphingolipids stimulate cell growth via MAP kinase activation in osteoblastic cells.

  1999cited by this paper
• Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase.

  1999cited by this paper
• Binding of phosphatidic acid to the protein-tyrosine phosphatase SHP-1 as a basis for activity modulation.

  1999cited by this paper
• Differential Phospholipase D Activation by Bradykinin and Sphingosine 1-Phosphate in NIH 3T3 Fibroblasts Overexpressing Gelsolin*

  1999cited by this paper
• Induction of Endothelial Cell Chemotaxis by Sphingosine 1-Phosphate and Stabilization of Endothelial Monolayer Barrier Function by Lysophosphatidic Acid, Potential Mediators of Hematopoietic Angiogenesis

  1999cited by this paper
• Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells.

  1999cited by this paper
• Regulation of NF-κB RelA Phosphorylation and Transcriptional Activity by p21 ras and Protein Kinase Cζ in Primary Endothelial Cells*

  1999cited by this paper
• Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms

  1998cited by this paper
• Signaling mechanisms and molecular characteristics of G protein‐coupled receptors for lysophosphatidic acid and sphingosine 1‐phosphate

  1998cited by this paper
• The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

  1998cited by this paper
• Inhibition of neutrophil-mediated acute inflammatory injury by an antibody against interleukin-8 (IL-8)

  1998cited by this paper
• Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

  1997cited by this paper
• Characterization of Two Alternately Spliced Forms of Phospholipase D1

  1997cited by this paper
• Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization.

  1997cited by this paper
• Activation of mitogen‐activated protein kinase is involved in sphingosine 1‐phosphate‐stimulated interleukin‐6 synthesis in osteoblasts

  1997cited by this paper
• Increased interleukin-8 concentrations in the pulmonary edema fluid of patients with acute respiratory distress syndrome from sepsis.

  1996cited by this paper
• Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways

  1996cited by this paper
• Raf-1 Kinase Possesses Distinct Binding Domains for Phosphatidylserine and Phosphatidic Acid

  1996cited by this paper
• Interleukin-8 in airway inflammation in patients with asthma and chronic obstructive pulmonary disease.

  1996cited by this paper
• Role of protein tyrosine phosphorylation in H2O2-induced activation of endothelial cell phospholipase D.

  1996cited by this paper
• Selective inhibition of phosphatidylinositol 3-kinase by phosphatidic acid and related lipids.

  1995cited by this paper
• The mitogen activated protein kinase signal transduction pathway: from the cell surface to the nucleus.

  1994cited by this paper
• Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids.

  1994cited by this paper
• Elevated IL-8 and MCP-1 in the bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis.

  1994cited by this paper
• Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid.

  1994cited by this paper
• Activation of endothelial cell phospholipase D by sphingosine and sphingosine-1-phosphate.

  1994cited by this paper
• Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase.

  1992cited by this paper
• Activation of NADPH-dependent superoxide production in plasma membrane extracts of pig neutrophils by phosphatidic acid.

  1988cited by this paper
• Phospholipase D.

  1978cited by this paper

• My Journey in Academia as a Lipid Biochemist

  2021cites this paper
• Proteomics of Select Neglected Tropical Diseases.

  2020cites this paper
• Roles for Phospholipase D1 in the Tumor Microenvironment.

  2020cites this paper
• Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation

  2020cites this paper
• Proteomic-based Studies on Leishmania

  2018cites this paper
• Intestinal Epithelial Cell-Specific Deletion of PLD2 Alleviates DSS-Induced Colitis by Regulating Occludin

  2017cites this paper
• On the role of bioactive sphingolipids and their metabolizing enzymes in cancer

  2017cites this paper
• Proteomic approaches for drug discovery against tegumentary leishmaniasis.

  2017cites this paper
• Using Proteomics to Understand How Leishmania Parasites Survive inside the Host and Establish Infection

  2016cites this paper
• Phospholipase D enzymes facilitate IL-17- and TNFα-induced expression of proinflammatory genes in rheumatoid arthritis synovial fibroblasts (RASF).

  2016cites this paper
• Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function.

  2016cites this paper
• Protein-Protein Interactions of Human Mitochondrial Amidoxime-Reducing Component in Mammalian Cells

  2016cites this paper
• PLD-Specific Small-Molecule Inhibitors Decrease Tumor-Associated Macrophages and Neutrophils Infiltration in Breast Tumors and Lung and Liver Metastases

  2016cites this paper
• Agonist‐induced activation of histamine H3 receptor signals to extracellular signal‐regulated kinases 1 and 2 through PKC‐, PLD‐, and EGFR‐dependent mechanisms

  2016cites this paper
• Cigarette smoke extract-induced interleukin-6 expression is regulated by phospholipase D1 in human bronchial epithelial cells.

  2016cites this paper
• New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection

  2015cites this paper
• Mammalian Phospholipase D: Structure, Regulation, and Physiological Function of Phospholipase D and its Link to Pathology

  2014cites this paper
• Sphingosine 1-Phosphate (S1P) Induced Interleukin-8 (IL-8) Release Is Mediated by S1P Receptor 2 and Nuclear Factor κB in BEAS-2B Cells

  2014cites this paper
• Lysophospholipid receptor activation of RhoA and lipid signaling pathways.

  2013cites this paper
• Phospholipase D signaling mediates reactive oxygen species-induced lung endothelial barrier dysfunction

  2013cites this paper
• Coronin 1B Regulates S1P-Induced Human Lung Endothelial Cell Chemotaxis: Role of PLD2, Protein Kinase C and Rac1 Signal Transduction

  2013influential citation
• Proteomic analysis reveals differentially expressed proteins in macrophages infected with Leishmania amazonensis or Leishmania major.

  2013cites this paper
• Rôle de la phospholipase D1 dans le trafic membranaire : implication dans le développement neuronal et l'exocytose régulée

  2013cites this paper
• NOD-like receptors mediated activation of eosinophils interacting with bronchial epithelial cells: a link between innate immunity and allergic asthma

  2013cites this paper
• Overexpression of phospholipase D enhances Bcl-2 expression by activating STAT3 through independent activation of ERK and p38MAPK in HeLa cells.

  2012cites this paper
• Sphingosine 1-phosphate elicits proinflammatory responses in ARPE-19 cells.

  2012cites this paper
• Photolysis of caged sphingosine-1-phosphate induces barrier enhancement and intracellular activation of lung endothelial cell signaling pathways.

  2011cites this paper
• Sphingosine-1-phosphate: a potential therapeutic target for rheumatoid arthritis

  2011cites this paper
• Phospholipase D1, but not D2, regulates protein secretion via Rho/ROCK in a Ras/Raf-independent, MEK-dependent manner in rat lacrimal gland.

  2011cites this paper
• Phospholipase D Signaling in T Cells

  2010cites this paper
• Phospholipase D2 acts as an important regulator in LPS-induced nitric oxide synthesis in Raw 264.7 cells.

  2010cites this paper
• IL-17A activation on bronchial epithelium and basophils: a novel inflammatory mechanism

  2009cites this paper
• House Dust Mite Allergen Der f 2-induced Phospholipase D1 Activation Is Critical for the Production of Interleukin-13 through Activating Transcription Factor-2 Activation in Human Bronchial Epithelial Cells*

  2009cites this paper
• Phospholipase D signalling and its involvement in neurite outgrowth.

  2009cites this paper
• Interleukin-17A activation on bronchial epithelium and basophils: a novel inflammatory mechanism

  2009cites this paper
• Expression profiles of the mouse lung identify a molecular signature of time-to-birth.

  2009cites this paper
• Phospholipase D-mediated Activation of IQGAP1 through Rac1 Regulates Hyperoxia-induced p47phox Translocation and Reactive Oxygen Species Generation in Lung Endothelial Cells*

  2009cites this paper
• Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.

  2009cites this paper
• Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury.

  2009cites this paper
• Sphingosine-1-phosphate increases human alveolar epithelial IL-8 secretion, proliferation and neutrophil chemotaxis.

  2009cites this paper
• Phospholipase D2 regulates endothelial permeability through cytoskeleton reorganization and occludin downregulation.

  2009cites this paper
• Signaling mechanisms of sphingosine 1-phosphate-induced ERK1/2 activation in cultured feline esophageal smooth muscle cells

  2008cites this paper
• Protein Kinase C-ϵ Regulates Sphingosine 1-Phosphate-mediated Migration of Human Lung Endothelial Cells through Activation of Phospholipase D2, Protein Kinase C-ζ, and Rac1*

  2008cites this paper
• Inhibition of Endothelial Interleukin-8 Production and Neutrophil Transmigration by Staphylococcus aureus Beta-Hemolysin

  2008cites this paper
• Involvement of phospholipase D in regulating expression of anti-microbial peptide human beta-defensin-2.

  2008cites this paper
• Cloning and characterization of phospholipase D from olive flounder (Paralichthys olivaceus).

  2008cites this paper
• Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages.

  2008cites this paper
• Phosphatidic acid as a regulator of matrix metalloproteinase‐9 expression via the TNF‐α signaling pathway

  2007cites this paper
• The role of sphingosine 1-phosphate in the TNF-alpha induction of IL-8 gene expression in lung epithelial cells.

  2007cites this paper
• α1‐Adrenergic Receptor Stimulation of Cell Motility Requires Phospholipase D‐Mediated Extracellular Signal‐Regulated Kinase Activation

  2007cites this paper
• Mechanisms of indomethacin-induced alterations in the choline phospholipid metabolism of breast cancer cells.

  2006cites this paper
• Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells.

  2006cites this paper
• Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells.

  2005cites this paper
• S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate.

  2005cites this paper
• The P2Y14 receptor of airway epithelial cells: coupling to intracellular Ca2+ and IL-8 secretion.

  2005cites this paper
• Sphingosylphosphorylcholine generates reactive oxygen species through calcium-, protein kinase Cdelta- and phospholipase D-dependent pathways.

  2005cites this paper
• Implication de la phospholipase D et de son produit, l'acide phosphatidique, dans la différenciation myogénique

  2004cites this paper
• Increased expression of two phospholipase D isoforms during experimentally induced hippocampal mossy fiber outgrowth

  2004cites this paper
• Differential role for phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate-stimulated MAPK activation, Cox-2 and IL-8 expression.

  2004cites this paper
• Modulation of adpative immune responses by sphingosine-1-phosphate

  2004cites this paper
• G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival

  2004cites this paper
• Modulation of adaptive immune responses by sphingosine-1-phosphate.

  2004cites this paper
• Phospholipase D1 Regulates Secretagogue-stimulated Insulin Release in Pancreatic β-Cells*

  2004cites this paper
• Phosphatidic Acid Regulates Systemic Inflammatory Responses by Modulating the Akt-Mammalian Target of Rapamycin-p70 S6 Kinase 1 Pathway*

  2003cites this paper
• Mitogen-Activated Protein Kinases in Endothelial Pathophysiology

  2003cites this paper
• Involvement of Phospholipase D2 in Lysophosphatidate-induced Transactivation of Platelet-derived Growth Factor Receptor-β in Human Bronchial Epithelial Cells*

  2003cites this paper