Preclinical study of boron neutron capture therapy for bone metastasis using human breast cancer cell lines.

Bone metastasis has a major impact on the quality of life that general therapy cannot control. We established a bone metastasis model with a human breast cancer cell line and investigated the therapeutic effect of boron neutron capture therapy (BNCT). BNCT suppressed tumor growth in cases of intramedullary small tumors without damaging normal tissues, providing preliminary evidence that it is a potentially new therapeutic option for controlling tumor growth from bone metastasis. Further research is warranted for its clinical application.

• Publication year

  2020

• Venue

  Applied Radiation and Isotopes

• Publication date

  2020-07-06

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.1016/j.apradiso.2020.109257PMID 32777739
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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