Identification of Cripto-1 as a Novel Serologic Marker for Breast and Colon Cancer

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Clinical Cancer Research

• Publication date

  2006-09-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1158/1078-0432.CCR-06-0274PMID 16951234
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Cripto-1: an oncofetal gene with many faces.

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  2003influential reference
• The role of EGF-related peptides in tumor growth.

  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1999cited by this paper
• Increased serum levels of transforming growth factor-α in patients with colorectal cancer

  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1994cited by this paper
• Gene alterations in intestinal metaplasia and gastric cancer.

  1994cited by this paper
• Identification and biological characterization of an epidermal growth factor-related protein: cripto-1.

  1994cited by this paper
• Elevated serum levels of transforming growth factor-alpha in breast cancer patients.

  1994cited by this paper
• Differential immunohistochemical detection of amphiregulin and cripto in human normal colon and colorectal tumors.

  1992cited by this paper
• Biosynthesis of carcinoembryonic antigen (CEA) gene family members expressed in human tumor cell lines: evidence for cleavage of the glycosyl phosphatidyl inositol (GPI) anchor by GPI-PLC and GPI-PLD.

  1991cited by this paper
• Expression of cripto, a novel gene of the epidermal growth factor gene family, leads to in vitro transformation of a normal mouse mammary epithelial cell line.

  1991cited by this paper

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• [Molecular Pathogenesis of Testicular Germ Cell Tumors].

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