Alpha 2-macroglobulin levels in normal human and keratoconus corneas.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Investigative Ophthalmology and Visual Science

• Publication date

  1994-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 7525507
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Alpha 2-macroglobulin is present in and synthesized by the cornea.

  1994cited by this paper
• Lysosomal enzyme and inhibitor levels in the human trabecular meshwork.

  1994cited by this paper
• Keratoconus corneas: increased gelatinolytic activity appears after modification of inhibitors.

  1993cited by this paper
• MMPs and proteinase inhibitors in the human aqueous humor.

  1993cited by this paper
• Collagenolytic/gelatinolytic metalloproteinases in normal and keratoconus corneas.

  1992cited by this paper
• α2“Macroglobulin, a multifunctional binding protein with targeting characteristics

  1992cited by this paper
• Proteoglycan molecules in keratoconus corneas.

  1991cited by this paper
• Binding of tumor necrosis factor alpha to activated forms of human plasma alpha 2 macroglobulin.

  1991cited by this paper
• Alpha-1 proteinase inhibitor levels in keratoconus.

  1990cited by this paper
• Differential inhibition of transforming growth factor beta 1 and beta 2 activity by alpha 2-macroglobulin.

  1990cited by this paper
• Interaction of hemorrhagic metalloproteinases with human alpha 2-macroglobulin.

  1990cited by this paper
• Evidence that the newly cloned low‐density‐lipoprotein receptor related protein (LRP) is the α2‐macroglobulin receptor

  1990cited by this paper
• Independent analysis of bait region cleavage dependent and thiolester bond cleavage dependent conformational changes by cross-linking of alpha 2-macroglobulin with cis-dichlorodiammineplatinum(II) and dithiobis(succinimidyl propionate).

  1989cited by this paper
• Identification of alpha 2-macroglobulin as a cytokine binding plasma protein. Binding of interleukin-1 beta to "F" alpha 2-macroglobulin.

  1989cited by this paper
• Preparation and initial characterization of an intermediate, half-cleaved form of human alpha 2-macroglobulin.

  1989cited by this paper
• Alpha 2-macroglobulin is a binding protein for basic fibroblast growth factor.

  1989cited by this paper
• Lysosomal enzyme abnormalities in keratoconus.

  1989cited by this paper
• Identification of alpha 2-macroglobulin as a carrier protein for IL-6.

  1989cited by this paper
• Keratoconus: I. Biochemical studies.

  1988cited by this paper
• Keratoconus

  1988cited by this paper
• Fluorescence-labeled lectins, glycoconjugates, and the development of the mouse AOP.

  1987cited by this paper
• Increase in type I and type IV collagenolytic activity in primary cultures of keratoconus cornea

  1986cited by this paper
• Biochemical studies of normal and keratoconus corneas

  1985cited by this paper
• RNA Metabolism in Cultures of Corneal Stromal Cells from Patients with Keratoconus

  1985cited by this paper
• Heterogeneity in Keratoconus: Possible Biochemical Basis

  1984cited by this paper
• Keratoconus and related noninflammatory corneal thinning disorders.

  1984cited by this paper
• Specific covalent binding of platelet-derived growth factor to human plasma alpha 2-macroglobulin.

  1984cited by this paper
• Cellular and biochemical mechanisms involved in the degradation and healing of the cornea. The polymorphonuclear leukocyte and tear fluid serum antiproteases in human melting central corneal ulcers.

  1984cited by this paper
• Structures and functions of lysosomal thiol proteinases and their endogenous inhibitor.

  1983cited by this paper
• Increased collagenase and gelatinase activities in keratoconus.

  1982cited by this paper
• Collagenolytic activity in keratoconus.

  1982cited by this paper
• Alpha 2-macroglobulin.

  1981cited by this paper
• Improved microfluorometric DNA determination in biological material using 33258 Hoechst.

  1979cited by this paper
• The interaction of α2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

  1973cited by this paper
• The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism.

  1973cited by this paper

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• Keratoconus patients exhibit a distinct ocular surface immune cell and inflammatory profile

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• Assessing the role of systemic inflammation in the etiopathogenesis of advanced stage keratoconus

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• Familial association of keratoconus and granular corneal dystrophy: The familial case series

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• Modern Pathogenesis of Keratoconus: Genomics and Proteomics

  2017cites this paper
• Morphologische Hornhautveränderungen nach Crosslinking bei Keratokonus

  2017cites this paper
• Morphologische Hornhautveränderungen nach Crosslinking bei Keratokonus Morphologic Corneal Changes after Crosslinking for Keratoconus

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• Differential Gene Transcription of Extracellular Matrix Components in Response to In Vivo Corneal Crosslinking (CXL) in Rabbit Corneas

  2017cites this paper
• Gene therapy in keratoconus

  2015cites this paper
• A study of stromal riboflavin absorption in ex vivo porcine corneas using new and existing delivery protocols for corneal cross‐linking

  2015cites this paper
• 8 – Cornea and Sclera

  2015cites this paper
• Corneal cross-linking treatment of keratoconus

  2015cites this paper
• Protective Effects of Soluble Collagen during Ultraviolet-A Crosslinking on Enzyme-Mediated Corneal Ectatic Models

  2015cites this paper
• Role of Protease-Inhibitors in Ocular Diseases

  2014cites this paper
• The pathogenesis of keratoconus

  2014cites this paper
• Understanding the structural basis of corneal refractive function and its modification via novel therapeutic approaches

  2014cites this paper
• Role of biochemical factors in the pathogenesis of keratoconus.

  2014cites this paper
• Keratoconus and crosslinking: pharmacokinetic considerations

  2013cites this paper
• What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease.

  2013cites this paper
• Assessment of the Macula in Keratoconus: An Optical Coherence Tomography and Multifocal Electroretinography Study

  2013cites this paper
• Collagenase-mediated tissue modeling of corneal ectasia and collagen cross-linking treatments.

  2012cites this paper
• What Causes Keratoconus?

  2012cites this paper
• Imaging and aberrometric analyses of diseases affecting biomechanical properties of the cornea Modern disgnostic methods of keratoconus

  2012cites this paper
• Etiology and Clinical Presentation of Astigmatism

  2012cites this paper
• Molecular Genetics of Corneal Disease

  2011cites this paper
• Differential epithelial and stromal protein profiles in keratoconus and normal human corneas.

  2011cites this paper
• Kollagenvernetzung mittels Riboflavin und UV-A-Strahlung (CXL) bei Keratokonus: Zwei-Jahres-Ergebnisse

  2011cites this paper
• [Corneal riboflavin/UV-A collagen cross-linking (CXL) in keratoconus: two-year results].

  2011cites this paper
• Keratoconus: a review.

  2010cites this paper
• eratoconus : A review iguel

  2010cites this paper
• Effects of Sp1 overexpression on cultured human corneal stromal cells

  2009cites this paper
• Histopathological study of 49 cases of keratoconus

  2008cites this paper
• Reduced expression of the gap junction protein Connexin 43 in keratoconus

  2008cites this paper
• Corneal activation of prothrombin to form thrombin, independent of vascular injury.

  2007cites this paper
• A study of corneal thickness, shape and collagen organisation in keratoconus using videokeratography and X-ray scattering techniques.

  2007cites this paper
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  2006cites this paper
• The Effect of Contact Lens Wear on the Ocular Surface Changes in Keratoconus

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  2005cites this paper
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  2005cites this paper
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• The fibrinolysis inhibitor alpha2-antiplasmin in the human cornea.

  2005cites this paper
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  2005cites this paper
• Asymmetric Keratoconus Attributed to Eye Rubbing

  2004cites this paper
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  2003cites this paper
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  2002cites this paper
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  2002cites this paper
• Is the corneal degradation in keratoconus caused by matrix‐metalloproteinases?

  2001cites this paper
• Keratocan Expression Is Increased in the Stroma of Keratoconus Corneas

  2001cites this paper
• Expression of type XII collagen and hemidesmosome-associated proteins in keratoconus corneas

  2001cites this paper
• Cell density regulated expression of transcription factor Sp1 in corneal stromal cultures.

  2001cites this paper
• Plasminogen Activators and Inhibitors in the Corneas of Mice Infected with Pseudomonas aeruginosa.

  2001cites this paper
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  2001cites this paper
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  2001cites this paper
• Involvement of Sp1 elements in the promoter activity of genes affected in keratoconus.

  2001cites this paper
• Normal expression levels of cathepsins, protease inhibitors, and Sp1 in conjunctival tissues from patients with keratoconus

  2000cites this paper
• Genetics of the Corneal Dystrophies: What We Have Learned in the Past Twenty-five Years

  2000cites this paper
• Levels of alpha1-proteinase inhibitor and alpha2-macroglobulin in the tear film of patients with keratoconus.

  1999cites this paper
• Changes in corneal morphology associated with chronic epithelial injury.

  1999cites this paper
• Enhanced expression of a transmembrane phosphotyrosine phosphatase (LAR) in keratoconus cultures and corneas.

  1999cites this paper
• Keratoglobus lesions in the eyes of rearing broiler breeders.

  1998cites this paper
• Surgically induced keratoglobus in pellucid marginal degeneration

  1998cites this paper
• Keratocyte apoptosis: implications on corneal wound healing, tissue organization, and disease.

  1998cites this paper
• Expression of degradative enzymes and protease inhibitors in corneas with keratoconus.

  1998cites this paper
• Lectin Binding in Normal, Scarred, and Keratoconus Corneas

  1998cites this paper
• Effects of ascorbic acid on levels of fibronectin, laminin and collagen type 1 in bovine trabecular meshwork in organ culture.

  1998cites this paper
• Keratoconus.

  1998cites this paper
• Three-dimensional scanning electron microscopic study of keratoconus corneas.

  1998cites this paper
• The expression of tenascin and fibronectin in keratoconus, scarred and normal human cornea

  1997cites this paper
• The antigen-bearing eye and the spleen are indispensable in maintaining anterior chamber-associated immune deviation.

  1997cites this paper
• The immunohistochemical composition of corneal basement membrane in keratoconus.

  1997cites this paper
• Collagen fibril orientation in the human corneal stroma and its implication in keratoconus.

  1997cites this paper
• Expression of transcription factors in keratoconus, a cornea-thinning disease.

  1997cites this paper
• Cathepsin G, acid phosphatase, and alpha 1-proteinase inhibitor messenger RNA levels in keratoconus corneas.

  1997cites this paper
• Normal Lysosomal Enzyme Staining in Skin Tissues of Patients with Keratoconus

  1996cites this paper
• Expression of wound healing and stress-related proteins in keratoconus corneas.

  1996cites this paper