In this review, we present modern aspects of etiology and pathogenesis of atherosclerosis. We describe the roles played by inflammatory cells, components of cellular response in allergic reactions, disturbances of carbohydrate metabolism, cellular aging, and infection at various stages of formation of atherosclerotic plaques. Special attention is given to the specific characteristics of atherosclerosis and calcification of coronary arteries. We show the influence of age and gender on the disease progression. The review includes information on the importance of myocardial bridges for the change of hemodynamics in segments of coronary arteries. The data presented indicate that differences in localization of atherosclerotic lesions between systems of the right and left coronary arteries depends on their hemodynamic, anatomical and physiological characteristics. According to the literature, anterior descending artery is more vulnerable in this respect.
[Specific Characteristics of Coronary Atherosclerosis].
S. V. Pykhteev,A. K. Lashevich,P. Bogdan,A. Belash
Published 2017 in Kardiologiia
ABSTRACT
PUBLICATION RECORD
- Publication year
2017
- Venue
Kardiologiia
- Publication date
2017-07-01
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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