Structural and mechanistic insights into microtubule end-binding proteins.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Current Opinion in Cell Biology

• Publication date

  2010-02-01

• Fields of study

  Biology, Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1016/j.ceb.2009.10.009PMID 19959349
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mammalian end binding proteins control persistent microtubule growth

  2009cited by this paper
• Minimal Plus-end Tracking Unit of the Cytoplasmic Linker Protein CLIP-170*

  2009cited by this paper
• Phosphoregulation of the budding yeast EB1 homologue Bim1p by Aurora/Ipl1p

  2009cited by this paper
• Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics.

  2009cited by this paper
• Microtubule plus-end tracking by CLIP-170 requires EB1

  2009cited by this paper
• An EB1-binding motif acts as a microtubule tip localization signal.

  2009cited by this paper
• Dynamic behavior of GFP–CLIP-170 reveals fast protein turnover on microtubule plus ends

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  2008cited by this paper
• STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER.

  2008cited by this paper
• CLIP-170 tracks growing microtubule ends by dynamically recognizing composite EB1/tubulin-binding sites

  2008cited by this paper
• Suppression of microtubule dynamic instability by the +TIP protein EB1 and its modulation by the CAP-Gly domain of p150glued.

  2008cited by this paper
• Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice

  2008cited by this paper
• EB1 regulates microtubule dynamics and tubulin sheet closure in vitro

  2008cited by this paper
• XMAP215 is a processive microtubule polymerase.

  2008cited by this paper
• The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment

  2007cited by this paper
• Reconstitution of a microtubule plus-end tracking system in vitro

  2007cited by this paper
• Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1.

  2007cited by this paper
• Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding.

  2007cited by this paper
• Discrete States of a Protein Interaction Network Govern Interphase and Mitotic Microtubule Dynamics

  2007cited by this paper
• Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition

  2007cited by this paper
• Structure-function relationship of CAP-Gly domains

  2007cited by this paper
• CLIP170 autoinhibition mimics intermolecular interactions with p150Glued or EB1

  2007cited by this paper
• Stu2p binds tubulin and undergoes an open-to-closed conformational change

  2006cited by this paper
• Assembly dynamics of microtubules at molecular resolution

  2006cited by this paper
• Microtubule plus-end loading of p150Glued is mediated by EB1 and CLIP-170 but is not required for intracellular membrane traffic in mammalian cells

  2006cited by this paper
• The Schizosaccharomyces pombe EB1 homolog Mal3p binds and stabilizes the microtubule lattice seam.

  2006cited by this paper
• Key interaction modes of dynamic +TIP networks.

  2006cited by this paper
• Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends

  2006cited by this paper
• Melanophilin and myosin Va track the microtubule plus end on EB1

  2005cited by this paper
• A vital role of tubulin-tyrosine-ligase for neuronal organization

  2005cited by this paper
• Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end

  2005cited by this paper
• Structural basis for the activation of microtubule assembly by the EB1 and p150Glued complex.

  2005cited by this paper
• CLAMP, a novel microtubule-associated protein with EB-type calponin homology.

  2005cited by this paper
• Structural insights into the EB1–APC interaction

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• Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization

  2004cited by this paper
• Crystal Structure of the Amino-terminal Microtubule-binding Domain of End-binding Protein 1 (EB1)*

  2003cited by this paper
• Crystal Structure of the Cytoskeleton-associated Protein Glycine-rich (CAP-Gly) Domain*

  2002cited by this paper
• M phase-specific kinetochore proteins in fission yeast: microtubule-associating Dis1 and Mtc1 display rapid separation and segregation during anaphase.

  2001cited by this paper
• Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

  2001cited by this paper
• The Interaction of TOGp with Microtubules and Tubulin*

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• Stu2p: A Microtubule-Binding Protein that Is an Essential Component of the Yeast Spindle Pole Body

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• APC binds to the novel protein EB1.

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• CLIP-170 links endocytic vesicles to microtubules.

  1992cited by this paper
• A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end

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• Reconfiguration of the Microtubule Network and Dynamics in Hypoxic Cancer Cells

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• Microtubule-Associated Proteins (MAPs) Are Multifunctional Cytoskeletal Proteins in the Testis That Regulate Spermatogenesis.

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• MARK2 and MARK4 regulate Sertoli cell BTB dynamics through microtubule and actin cytoskeletons.

  2022cites this paper
• SxIP binding disrupts the constitutive homodimer interface of EB1, and stabilizes EB1 monomer.

  2021cites this paper
• Phylogeny and structural peculiarities of the EB proteins of diatoms.

  2021cites this paper
• Kinesin-5 Regulation and Function in Mitosis.

  2019cites this paper
• Role of microtubule +TIPs and -TIPs in spermatogenesis - insights from studies of toxicant models.

  2019cites this paper
• Crocin, a carotenoid, suppresses spindle microtubule dynamics and activates the mitotic checkpoint by binding to tubulin

  2019cites this paper
• Structure-Function Relationship of the Bik1-Bim1 Complex.

  2018cites this paper
• CLIP-170 is essential for MTOC repositioning during T cell activation by regulating dynein localisation on the cell surface

  2018cites this paper
• The kinetoplastid kinetochore protein KKT4 is an unconventional microtubule tip–coupling protein

  2018cites this paper
• Characterization of a novel EB1 acetylation site important for the regulation of microtubule dynamics and cargo recruitment

  2018cites this paper
• IMPROVING PROSTATE BIOPSIES WITH MRI-TRUS FUSION GUIDED BIOPSY

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• Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy

  2018cites this paper
• The unconventional kinetoplastid kinetochore protein KKT4 tracks with dynamic microtubule tips

  2017cites this paper
• Short Linear Sequence Motif LxxPTPh Targets Diverse Proteins to Growing Microtubule Ends.

  2017cites this paper
• Mini Spindles TOG1 Maintains Microtubule Polymerization Rates and Mitotic Spindle Formation

  2017cites this paper
• Conditional knockout of TOG results in CNS hypomyelination

  2017cites this paper
• Microtubule associated protein END BINDING 1b: functional domain deletions and root responses to mechanical stimuli

  2016cites this paper
• Molecular basis of Kar9-Bim1 complex function during mating and spindle positioning

  2016cites this paper
• ASK1 controls spindle orientation and positioning by phosphorylating EB1 and stabilizing astral microtubules

  2016cites this paper
• Understanding force-generating microtubule systems through in vitro reconstitution

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• ROS1 fusions in cancer: a review.

  2016cites this paper
• Escape from Mitotic Arrest: An Unexpected Connection Between Microtubule Dynamics and Epigenetic Regulation of Centromeric Chromatin in Schizosaccharomyces pombe

  2015cites this paper
• The Evolution of Microtubule End-Binding Protein 1 (EB1) and Roles in Regulating Microtubule Behavior

  2015cites this paper
• Characterising novel mitotic microtubule associated proteins in the early Drosophila embryo

  2015cites this paper
• Tubulin and Microtubules

  2015cites this paper
• Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubule-associated protein ATIP3

  2015cites this paper
• EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study.

  2015cites this paper
• Nucleation and Dynamics of Golgi-derived Microtubules

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• Building the Microtubule Cytoskeleton Piece by Piece*

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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2012cites this paper
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• Estimating Microtubule Distributions from 2D Immunofluorescence Microscopy Images Reveals Differences among Human Cultured Cell Lines

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• Mitotic Spindle Form and Function

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• Reconstitution of dynamic microtubules with Drosophila XMAP215, EB1, and Sentin

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• Fission yeast Alp14 is a dose-dependent plus end–tracking microtubule polymerase

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• Multisite Phosphorylation Disrupts Arginine-Glutamate Salt Bridge Networks Required for Binding of Cytoplasmic Linker-associated Protein 2 (CLASP2) to End-binding Protein 1 (EB1)*

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• Sequence Determinants of a Microtubule Tip Localization Signal (MtLS)*

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• In Vivo Roles of the Basic Domain of Dynactin p150 in Microtubule Plus‐End Tracking and Dynein Function

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• +TIPs: SxIPping along microtubule ends.

  2012cites this paper
• Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150(glued).

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• Kebab: Kinetochore and EB1 Associated Basic Protein That Dynamically Changes Its Localisation during Drosophila Mitosis

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