The heart has the highest energy demands per gram of any organ in the body and energy metabolism fuels normal contractile function. Metabolic inflexibility and impairment of myocardial energetics occur with several common cardiac diseases, including ischemia and heart failure. This review explores several decades of innovation in cardiac magnetic resonance spectroscopy modalities and their use to noninvasively identify and quantify metabolic derangements in the normal, failing, and diseased heart. The implications of this noninvasive modality for predicting significant clinical outcomes and guiding future investigation and therapies to improve patient care are discussed.
Measuring Myocardial Energetics with Cardiovascular Magnetic Resonance Spectroscopy.
J. Sourdon,S. Lewsey,M. Schär,R. Weiss
Published 2021 in Heart Failure Clinics
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- Publication year
2021
- Venue
Heart Failure Clinics
- Publication date
2021-01-01
- Fields of study
Medicine, Engineering
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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