Knockdown of hypoxia‐inducible factor‐1α by siRNA inhibits C2C12 myoblast differentiation

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Cellular Biochemistry

• Publication date

  2006-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/jcb.20804PMID 16440321
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Adaptive Myogenesis under Hypoxia

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• PI3K/Akt Is Required for Heat Shock Proteins to Protect Hypoxia-inducible Factor 1α from pVHL-independent Degradation*

  2004cited by this paper
• Loss of Skeletal Muscle HIF-1α Results in Altered Exercise Endurance

  2004cited by this paper
• Cellular and molecular regulation of muscle regeneration.

  2004cited by this paper
• Hypoxia-inducible factor (HIF-1)α: its protein stability and biological functions

  2004cited by this paper
• Defective brain development in mice lacking the Hif-1alpha gene in neural cells.

  2003cited by this paper
• FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts

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• HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland.

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  2003cited by this paper
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• Defective Brain Development in Mice Lacking the Hif-1α Gene in Neural Cells

  2003cited by this paper
• Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia.

  2002cited by this paper
• Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells.

  2002cited by this paper
• Effects of resistance exercise combined with moderate vascular occlusion on muscular function in humans.

  2000influential reference
• NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia.

  2000cited by this paper
• Pax7 is required for the specification of myogenic satellite cells.

  2000cited by this paper
• Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein

  2000cited by this paper
• Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3)

  2000cited by this paper
• Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3

  2000cited by this paper
• Hypoxia‐induced activation of HIF‐1: role of HIF‐1α‐Hsp90 interaction

  1999cited by this paper
• Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction.

  1999cited by this paper
• Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90.

  1999cited by this paper
• Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.

  1999cited by this paper
• The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity.

  1999cited by this paper
• The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

  1999cited by this paper
• Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway.

  1998cited by this paper
• Insulin induces transcription of target genes through the hypoxia‐inducible factor HIF‐1α/ARNT

  1998cited by this paper
• An essential role of phosphatidylinositol 3-kinase in myogenic differentiation.

  1998cited by this paper
• Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha.

  1998cited by this paper
• Regulation of hypoxia-inducible factor 1α is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

  1998cited by this paper
• Heat‐shock protein 90 and ubiquitin: Developmental regulation during myogenesis

  1996cited by this paper
• MyoD or Myf-5 is required for the formation of skeletal muscle.

  1993cited by this paper
• Functional antagonism between c-Jun and MyoD proteins: a direct physical association.

  1992cited by this paper
• A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts.

  1989cited by this paper
• Identification of MRF4: a new member of the muscle regulatory factor gene family.

  1989cited by this paper
• Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD.

  1989cited by this paper

• Hypoxia and Tissue Regeneration: Adaptive Mechanisms and Therapeutic Opportunities

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• Rab44 negatively regulates myoblast differentiation by controlling fusogenic protein transport and mTORC1 signaling

  2023cites this paper
• Effective drug and shRNA delivery for synergistic treatment of triple-negative breast cancer by sequentially targeting tumor hypoxia

  2023cites this paper
• Down-regulated Smyd1 participated in the inhibition of myoblast differentiation induced by cigarette smoke extract.

  2023cites this paper
• Kaempferol increases intracellular ATP content in C2C12 myotubes under hypoxic conditions by suppressing the HIF-1α stabilization and/or by enhancing the mitochondrial complex IV activity.

  2022cites this paper
• Investigation on the Effect of Cyclic Stretch and Hypoxia on Recovery of Damaged Skeletal Muscle Cells Using Microfluidic System

  2021cites this paper
• HIF-1α Negatively Regulates Irisin Expression Which Involves in Muscle Atrophy Induced by Hypoxia

  2021cites this paper
• Hypoxia transactivates cholecystokinin gene expression in 3D-engineered muscle.

  2021cites this paper
• Hypoxic Signaling in Skeletal Muscle Maintenance and Regeneration: A Systematic Review

  2021cites this paper
• Moderate hypoxia promotes skeletal muscle cell growth and hypertrophy in C2C12 cells.

  2020cites this paper
• Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice

  2020cites this paper
• EDMD-Causing Emerin Mutant Myogenic Progenitors Exhibit Impaired Differentiation Using Similar Mechanisms

  2020cites this paper
• Uremic Sarcopenia: Clinical Evidence and Basic Experimental Approach

  2020cites this paper
• Role of hypoxia in skeletal muscle fibrosis: Synergism between hypoxia and TGF-β signaling upregulates CCN2/CTGF expression specifically in muscle fibers.

  2020cites this paper
• HIF-hypoxia signaling in skeletal muscle physiology and fibrosis

  2020cites this paper
• HIF1α-dependent mitophagy facilitates cardiomyoblast differentiation

  2020cites this paper
• A Three-Dimensional Culture Model of Reversibly Quiescent Myogenic Cells

  2019cites this paper
• The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate

  2019cites this paper
• Characterization of Wilms' Tumour 1 (Wt1) as a Biomarker for Fibrosis in Duchenne Muscular Dystrophy

  2019cites this paper
• Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration

  2018cites this paper
• Regulation of fibrosis in muscular dystrophy.

  2018cites this paper
• Ischemic preconditioning in skeletal muscle.

  2017cites this paper
• A Transcriptomic Analysis of Physiological Significance of Hypoxia-inducible Factor-1α in Myogenesis and Carbohydrate Metabolism of Genioglossus in Mice

  2017cites this paper
• The hypoxia-inducible factors HIF1α and HIF2α are dispensable for embryonic muscle development but essential for postnatal muscle regeneration

  2017cites this paper
• Regulation of myogenesis and skeletal muscle regeneration: effects of oxygen levels on satellite cell activity

  2016influential citation
• Effects of Hypoxic Conditions on Skeletal Myoblasts

  2016cites this paper
• Syddansk Universitet Low Oxygen Tension Enhances Expression of Myogenic Genes When Human Myoblasts Are Activated from G 0 Arrest

  2016influential citation
• University of Southern Denmark Low Oxygen Tension Enhances Expression of Myogenic Genes When Human Myoblasts Are Activated from G 0

  2016influential citation
• Low Oxygen Tension Enhances Expression of Myogenic Genes When Human Myoblasts Are Activated from G0 Arrest

  2016influential citation
• Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway

  2015cites this paper
• Hypoxia‐inducible factor‐1α mediates up‐regulation of neprilysin by histone deacetylase‐1 under hypoxia condition in neuroblastoma cells

  2014cites this paper
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  2013cites this paper
• HIF mediated and DNA damage independent histone H2AX phosphorylation in chronic hypoxia

  2013cites this paper
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  2013cites this paper
• Hypoxia-inducible Factor 1-α Induces miR-210 in Normoxic Differentiating Myoblasts*

  2012cites this paper
• Phosphatidylinositol-3-kinase (PI3K) activity decreases in C2C12 myotubes during acute simulated ischemia at a cost to their survival.

  2012cites this paper
• Evidence for cell density affecting C2C12 myogenesis: possible regulation of myogenesis by cell–cell communication

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• Synthetic Matrices to Serve as Niches for Muscle Cell Transplantation

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• Differential Responses of Myogenic C2C12 Cells to Hypoxia between Growth and Muscle-Induction Phases : Growth, Differentiation and Motility

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  2009cites this paper
• Decreased muscle atrophy F‐box (MAFbx) expression in regenerating muscle after muscle‐damaging exercise

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• Oxidative stress in muscle progenitor cell function

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• Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation.

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• Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3.

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  2007cites this paper
• Notch2 negatively regulates myofibroblastic differentiation of myoblasts

  2007cites this paper
• Effects of hypoxia on proliferation and differentiation of myoblasts.

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• Hypoxia-inducible Factor 1α (HIF-1α)-mediated Hypoxia Increases BACE1 Expression and β-Amyloid Generation*

  2007cites this paper