The translation initiation factor, hu-Sui1 may be a target of hepatitis B X antigen in hepatocarcinogenesis

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Oncogene

• Publication date

  1999-03-04

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.onc.1202470PMID 10208429
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Animal virus genetics

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• X-gene Product of Hepatitis B Virus Induces Apoptosis in Liver Cells*

  1998cited by this paper
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  1998influential reference
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  1998cited by this paper
• The hepatitis B virus X gene induces p53-mediated programmed cell death.

  1997cited by this paper
• AN INTERNATIONAL SYMPOSIUM

  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
• Gas Exchange and Growth

  1995cited by this paper
• Notch signaling.

  1995cited by this paper
• Genetic heterogeneity of hepatocellular carcinoma: Unsal H, Yakicier C, Marcais C, Kew M, Volkmann M, Zentgraf H, Isselbacher KJ, et al Proc Natl Acad Sci U S A 1994;91:822–826

  1995cited by this paper
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  1995cited by this paper
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  1995influential reference
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  1994influential reference
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  1993cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1991cited by this paper
• Participation of p53 protein in the cellular response to DNA damage.

  1991cited by this paper
• HBxAg in the liver from carrier patients with chronic hepatitis and cirrhosis

  1991influential reference
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  1991cited by this paper
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  1991cited by this paper
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  1991influential reference
• In vitro tumorigenicity of hepatitis B virus DNA and HBx protein.

  1991cited by this paper
• Characteristics of hepatitis B X antigen, antibodies to X antigen, and antibodies to the viral polymerase during hepatitis B virus infection.

  1991cited by this paper
• Monoclonal antibodies raised to purified woodchuck hepatitis virus core antigen particles demonstrate X antigen reactivity.

  1990influential reference
• Malignant transformation of immortalized transgenic hepatocytes after transfection with hepatitis B virus DNA.

  1990cited by this paper
• Integration of hepatitis B virus DNA and its implications for hepatocarcinogenesis.

  1990cited by this paper
• X antigen polypeptides in the sera of hepatitis B virus-infected patients.

  1990influential reference
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  1990cited by this paper
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  1987cited by this paper
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  1986cited by this paper
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  1982cited by this paper
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  1980cited by this paper
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  1980cited by this paper
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  1979cited by this paper

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