Down‐regulation of aortic and cardiac AT1 receptor gene expression in transgenic (mRen‐2) 27 rats

No abstract is available for this paper.

• Publication year

  1997

• Venue

  British Journal of Pharmacology

• Publication date

  1997-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.bjp.0701088PMID 9146897PMCID PMC1564644
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Enhanced angiotensin receptor type 1 mRNA degradation and induction of polyribosomal mRNA binding proteins by angiotensin II in vascular smooth muscle cells.

  1996cited by this paper
• Regulation, chamber localization, and subtype distribution of angiotensin II receptors in human hearts.

  1995cited by this paper
• Effects of angiotensin II and angiotensin-converting enzyme inhibitors on human myocardium.

  1995cited by this paper
• Angiotensin II induces cardiac phenotypic modulation and remodeling in vivo in rats.

  1995cited by this paper
• Species‐related differences in inotropic effects of angiotensin II in mammalian ventricular muscle: receptors, subtypes and phosphoinositide hydrolysis

  1995cited by this paper
• Contractile properties of left ventricular myocytes isolated from spontaneously hypertensive rats: effect of angiotensin II

  1995cited by this paper
• Haemodynamic effects of losartan and the endothelin antagonist, SB 209670, in conscious, transgenic ((mRen‐2)27), hypertensive rats

  1995cited by this paper
• Angiotensin II down-regulates the vascular smooth muscle AT1 receptor by transcriptional and post-transcriptional mechanisms: evidence for homologous and heterologous regulation.

  1995cited by this paper
• Endothelin, endothelin receptors, and endothelin antagonists.

  1994cited by this paper
• Functional vascular renin-angiotensin system in hypertensive transgenic rats for the mouse renin gene Ren-2.

  1994cited by this paper
• Mechanisms of hypertension in transgenic rats expressing the mouse Ren-2 gene.

  1994cited by this paper
• Down-regulation by growth factors of vascular smooth muscle angiotensin receptor gene expression.

  1994cited by this paper
• Angiotensin I and II exert inotropic effects in atrial but not in ventricular human myocardium. An in vitro study under physiological experimental conditions.

  1993cited by this paper
• Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

  1993cited by this paper
• High blood pressure maintenance in transgenic mRen-2 vs. Lyon genetically hypertensive rats.

  1993cited by this paper
• Pharmacological characteristics of the positive inotropic effect of angiotensin II in the rabbit ventricular myocardium

  1993cited by this paper
• Increased Vascular Angiotensin Formation in Female Rats Harboring the Mouse Ren‐2 Gene

  1992cited by this paper
• Contractile properties of ventricular myocytes isolated from spontaneously hypertensive rat

  1992cited by this paper
• Transgenic Rats: New Animal Models in Hypertension Research Invited Lecture

  1991influential reference
• Beta 1- and beta 2-adrenoceptors in the human heart: properties, function, and alterations in chronic heart failure.

  1991cited by this paper
• Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene

  1990influential reference
• Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells.

  1990cited by this paper
• Angiotensins and the failing heart. Enhanced positive inotropic response to angiotensin I in cardiomyopathic hamster heart in the presence of captopril.

  1990cited by this paper
• Isolated myocardial cells: a new tool for the investigation of hypertensive heart disease.

  1990cited by this paper
• Agonist-induced destabilization of beta-adrenergic receptor mRNA. Attenuation of glucocorticoid-induced up-regulation of beta-adrenergic receptors.

  1989cited by this paper
• Reduction of beta-adrenoceptor density and evaluation of positive inotropic responses in isolated, diseased human myocardium.

  1988cited by this paper
• Identification and Characterization of Guinea Pig Angiotensin II Ventricular and Atrial Receptors: Coupling to Inositol Phosphate Production

  1988cited by this paper
• Mechanism of sodium modulation of glomerular angiotensin receptors in the rat.

  1984cited by this paper
• Effect of angiotensin II and deoxycorticosterone infusion on vascular angiotensin II receptors in rats.

  1984cited by this paper
• High affinity angiotensin II receptors in myocardial sarcolemmal membranes. Characterization of receptors and covalent linkage of 125I-angiotensin II to a membrane component of 116,000 daltons.

  1984cited by this paper
• Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts.

  1982cited by this paper
• Relation of the Renin‐Angiotensin-Aldosterone System to Clinical State in Congestive Heart Failure

  1981cited by this paper
• Regulation of Vascular Angiotensin II Receptors in the Rat during Altered Sodium Intake

  1981cited by this paper
• Regulation by angiotensin II of its receptors in resistance blood vessels

  1980cited by this paper
• Positive chronotropic and inotropic effects of angiotensin II in the dog heart.

  1978cited by this paper
• Renin-angiotensin system: biochemistry and mechanisms of action.

  1977cited by this paper
• Mechanism for the Positive Inotropic Effect of Angiotensin II on Isolated Cardiac Muscle

  1976cited by this paper
• Wall stress and patterns of hypertrophy in the human left ventricle.

  1975cited by this paper
• Role of blood pressure in the development of congestive heart failure. The Framingham study.

  1972cited by this paper
• Direct myocardial effects of angiotensin II.

  1971cited by this paper
• Contractile State of Cardiac Muscle Obtained from Cats with Experimentally Produced Ventricular Hypertrophy and Heart Failure

  1967cited by this paper

• Alamandine enhances cardiomyocyte contractility in hypertensive rats through a NO-dependent activation of CaMKII.

  2020cites this paper
• Functional Analysis of the Promoter Region of Japanese Flounder (Paralichthys olivaceus) β-actin Gene: A Useful Tool for Gene Research in Marine Fish

  2018cites this paper
• Differences in Cardiovascular Responses to Alamandine in Two-Kidney, One Clip Hypertensive and Normotensive Rats.

  2017cites this paper
• Endogenous hydrogen sulfide is associated with angiotensin II type 1 receptor in a rat model of carbon tetrachloride-induced hepatic fibrosis

  2015cites this paper
• [Renin-angiotensin system gene expression in the kidney and in the heart in hypertensive ISIAH rats].

  2011cites this paper
• Chronic angiotensin receptor blockade suppresses intracardiac angiotensin II in angiotensin II-infused rats

  2011cites this paper
• Expression of the renin angiotensin system genes in the kidney and heart of ISIAH hypertensive rats

  2011cites this paper
• Atrap deficiency increases arterial blood pressure and plasma volume.

  2010cites this paper
• Transforming growth factor β1 mediates apoptotic activity of angiotensin II type I receptor blocker on prostate epithelium in vitro

  2010cites this paper
• Untersuchungen zur Regulation des Endothelin-1-Gens

  2009cites this paper
• Gene Expression for the Renin System in the Myocardium of Hypertensive ISIAH Rats

  2009cites this paper
• Expression of Angiotensin II Receptor Type 1 Is Reduced in Advanced Rat Liver Fibrosis

  2007cites this paper
• Inverse Blood Pressure Rhythm of Transgenic Hypertensive TGR(mREN2)27 Rats: Role of Norepinephrine and Expression of Tyrosine‐Hydroxylase and Reuptake1‐Transporter

  2005cites this paper
• Over-expression of angiotensin converting enzyme-1 augments cardiac hypertrophy in transgenic rats.

  2004cites this paper
• Arterial stiffness and angiotensinogen gene in hypertensive patients and mutant mice

  2004cites this paper
• Regulation of angiotensin II receptors in the prostate of the transgenic (mRen-2)27 rat: effect of angiotensin-converting enzyme inhibition.

  2003cites this paper
• Transgenic TGR(mREN2)27 Rats as a Model for Disturbed Circadian Organization at the Level of the Brain, the Heart, and the Kidneys

  2003influential citation
• Renin, angiotensin, sodium and organ damage.

  2003cites this paper
• Activation and Functional Significance of the Renin-Angiotensin System in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor

  2003cites this paper
• Transduction of a Functional Domain of the AT1 Receptor in Neurons by HIV-Tat PTD

  2003cites this paper
• Angiotensin‐(1‐7) is involved in the endothelium‐dependent modulation of phenylephrine‐induced contraction in the aorta of mRen‐2 transgenic rats

  2002cites this paper
• Evidence for activation of the renin–angiotensin system in the human prostate: increased angiotensin II and reduced AT1 receptor expression in benign prostatic hyperplasia

  2002cites this paper
• Involvement of cysteinyl leukotrienes in angiotensin II-induced contraction in isolated aortas from transgenic (mRen-2)27 rats

  2002cites this paper
• Downregulation of the AT1A Receptor by Pharmacologic Concentrations of Angiotensin-(1-7)

  2001cites this paper
• Identification, distribution, and expression of angiotensin II receptors in the normal human prostate and benign prostatic hyperplasia.

  2001cites this paper
• DAY-NIGHT VARIATION IN THE IN VITRO CONTRACTILITY OF AORTA AND MESENTERIC AND RENAL ARTERIES IN TRANSGENIC HYPERTENSIVE RATS*

  2001cites this paper
• CHAPTER 35 – Cardiac Action of Angiotensin II

  2001cites this paper
• INFLUENCE OF CIRCADIAN TIME AND AGE ON GLOMERULAR ANGIOTENSIN II RECEPTORS IN NORMOTENSIVE SPRAGUE-DAWLEY AND TRANSGENIC HYPERTENSIVE TGR(mREN2)27 RATS

  2001cites this paper
• International union of pharmacology. XXIII. The angiotensin II receptors.

  2000cites this paper
• Cardiac angiotensin II receptors are downregulated by chronic angiotensin II infusion in rats.

  2000cites this paper
• Genetic mapping of modifier loci affecting malignant hypertension in TGRmRen2 rats.

  1999cites this paper
• AT1 receptor regulation in salt-sensitive hypertension.

  1999cites this paper
• Differential response of angiotensin peptides in the urine of hypertensive animals.

  1999cites this paper
• Cardiovascular responses to angiotensins I and II in normotensive and hypertensive rats; effects of NO synthase inhibition or ET receptor antagonism

  1999cites this paper
• Roles of AT1 and AT2 receptors in the hypertensive Ren-2 gene transgenic rat kidney.

  1999cites this paper
• Arterieller Hypertonus und das Renin-Angiotensin-System — genetische und transgene Studien

  1999cites this paper
• Enhanced renal vascular responsiveness to angiotensin II in hypertensive ren-2 transgenic rats.

  1999cites this paper
• Alteration of intracellular Ca2(+)-handling and receptor regulation in hypertensive cardiac hypertrophy: insights from Ren2-transgenic rats.

  1998cites this paper
• Enhanced involvement of endothelin in the haemodynamic sequelae of endotoxaemia in conscious, hypertensive, transgenic ((mRen‐2)27) rats

  1998cites this paper
• Cardiac Specific Expression of AT1 Receptors in Experimental Heart Failure

  1998cites this paper
• The TGR(mRen2)27 transgenic rat model of hypertension.

  1998cites this paper
• Adrenal, kidney, and heart angiotensins in female murine Ren-2 transfected hypertensive rats.

  1998cites this paper
• Effects of taurine on signal transduction steps induced during hypertrophy of rat heart myocytes.

  1998cites this paper
• Hypertension and the renin-angiotensin system – evidence from genetic and transgenic studies

  1998cites this paper
• Estrogen modulates AT1 receptor gene expression in vitro and in vivo.

  1998cites this paper
• NK1 receptor antagonist blocks angiotensin II responses in renin transgenic rat medulla oblongata.

  1998cites this paper