Nonserotonergic projection neurons in the midbrain raphe nuclei contain the vesicular glutamate transporter VGLUT3

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Synapse

• Publication date

  2009-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/syn.20581PMID 18925658
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Serotonin: a review.

  2008cited by this paper
• Median raphe stimulation disrupts hippocampal theta via rapid inhibition and state-dependent phase reset of theta-related neural circuitry.

  2008cited by this paper
• Two distinct subtypes of serotonergic fibers classified by co-expression with vesicular glutamate transporter 3 in rat forebrain.

  2008cited by this paper
• The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone

  2008cited by this paper
• Selective anterograde tracing of the individual serotonergic and nonserotonergic components of the dorsal raphe nucleus projection to the vestibular nuclei.

  2007cited by this paper
• Synapse‐specific localization of vesicular glutamate transporters in the rat olfactory bulb

  2007cited by this paper
• Movement-related correlates of single cell activity in the interpeduncular nucleus and habenula of the rat during a pellet-chasing task.

  2006cited by this paper
• Colocalization of serotonin and vesicular glutamate transporter 3-like immunoreactivity in the midbrain raphe of Syrian hamsters (Mesocricetus auratus).

  2006cited by this paper
• Stereological estimates of the basal forebrain cell population in the rat, including neurons containing choline acetyltransferase, glutamic acid decarboxylase or phosphate-activated glutaminase and colocalizing vesicular glutamate transporters.

  2006cited by this paper
• Vesicular glutamate transporter 3 immunoreactivity is present in cholinergic basal forebrain neurons projecting to the basolateral amygdala in rat

  2006influential reference
• GABAergic control of the ascending input from the median raphe nucleus to the limbic system.

  2005cited by this paper
• The activation of raphe serotonergic neurons in normal and hypoarousal-driven aggression: a double labeling study in rats.

  2005cited by this paper
• Peptides that fine-tune the serotonin system.

  2005cited by this paper
• Characterization of medial septal glutamatergic neurons and their projection to the hippocampus

  2005cited by this paper
• A functional glutamatergic neurone network in the medial septum and diagonal band area

  2005cited by this paper
• Frequent coexpression of the vesicular glutamate transporter 1 and 2 genes, as well as coexpression with genes for choline acetyltransferase or glutamic acid decarboxylase in neurons of rat brain

  2005cited by this paper
• Non-serotonergic dorsal and median raphe projection onto parvalbumin- and calbindin-containing neurons in hippocampus and septum.

  2004influential reference
• Cyclic AMP-Dependent Protein Kinase Catalytic Subunits Have Divergent Roles in Virulence Factor Production in Two Varieties of the Fungal Pathogen Cryptococcus neoformans

  2004cited by this paper
• Projections between the interpeduncular nucleus and basal forebrain in the rat as demonstrated by the anterograde and retrograde transport of WGA-HRP

  2004cited by this paper
• Localization of VGLUT3, the vesicular glutamate transporter type 3, in the rat brain.

  2004cited by this paper
• GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat

  2004cited by this paper
• Chemically specific circuit composed of vesicular glutamate transporter 3- and preprotachykinin B-producing interneurons in the rat neocortex.

  2004cited by this paper
• Intrinsic vesicular glutamate transporter 2‐immunoreactive input to septohippocampal parvalbumin‐containing neurons: Novel glutamatergic local circuit cells

  2004cited by this paper
• Projections from the raphe nuclei to the suprachiasmatic nucleus of the rat.

  2003influential reference
• Distribution of vesicular glutamate transporter-2 messenger ribonucleic Acid and protein in the septum-hypothalamus of the rat.

  2003cited by this paper
• Distinct electrophysiological properties of glutamatergic, cholinergic and GABAergic rat septohippocampal neurons: novel implications for hippocampal rhythmicity

  2003cited by this paper
• Interneuron Diversity series: Rhythm and mood in perisomatic inhibition.

  2003cited by this paper
• The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate

  2002influential reference
• A Third Vesicular Glutamate Transporter Expressed by Cholinergic and Serotoninergic Neurons

  2002influential reference
• Molecular Cloning and Functional Identification of Mouse Vesicular Glutamate Transporter 3 and Its Expression in Subsets of Novel Excitatory Neurons*

  2002cited by this paper
• Possible glutamatergic/aspartatergic projections to the supramammillary nucleus and their origins in the rat studied by selective [(3)H]D-aspartate labelling and immunocytochemistry.

  2002cited by this paper
• Median raphe serotonergic innervation of medial septum/diagonal band of Broca (MSDB) parvalbumin‐containing neurons: Possible involvement of the MSDB in the desynchronization of the hippocampal EEG

  1999cited by this paper
• Central mechanisms of pain modulation.

  1999cited by this paper
• Medial septal and median raphe innervation of vasoactive intestinal polypeptide-containing interneurons in the hippocampus.

  1999cited by this paper
• Projections of the median raphe nucleus in the rat

  1999influential reference
• A review of central 5-HT receptors and their function.

  1999cited by this paper
• Raphe serotonergic neurons projecting to the olfactory bulb contain galanin or somatostatin but not neurotensin.

  1999cited by this paper
• Neuronal activity of the septal pacemaker of theta rhythm under the influence of stimulation and blockade of the median raphe nucleus in the awake rabbit.

  1999cited by this paper
• Hippocampal EEG and unit activity responses to modulation of serotonergic median raphe neurons in the freely behaving rat.

  1999cited by this paper
• Reduction of the extracellular level of glutamate in the median raphe nucleus associated with hippocampal theta activity in the anaesthetized rat.

  1998cited by this paper
• Origin of the neurotensinergic innervation of the rat basal forebrain studied by retrograde transport of cholera toxin

  1998cited by this paper
• Neuronal projections from the mesencephalic raphe nuclear complex to the suprachiasmatic nucleus and the deep pineal gland of the golden hamster (Mesocricetus auratus)

  1998influential reference
• Dissociation of hippocampal serotonin release and locomotor activity following pharmacological manipulations of the median raphe nucleus.

  1997cited by this paper
• Hippocampal interneurons are excited via serotonin-gated ion channels.

  1997cited by this paper
• The 5-HT3 Receptor Is Present in Different Subpopulations of GABAergic Neurons in the Rat Telencephalon

  1997cited by this paper
• Medial septal unit firing characteristics following injections of 8-OH-DPAT into the median raphe nucleus.

  1996cited by this paper
• Differential serotonergic innervation of the suprachiasmatic nucleus and the intergeniculate leaflet and its role in circadian rhythm modulation

  1996cited by this paper
• Response of serotonergic caudal raphe neurons in relation to specific motor activities in freely moving cats

  1995cited by this paper
• Extent of colocalization of serotonin and GABA in the neurons of the rat raphe nuclei.

  1995influential reference
• Effects of 5-HT3 receptor antagonism on hippocampal theta rhythm, memory, and LTP induction in the freely moving rat

  1995cited by this paper
• Injections of muscimol into the median raphe nucleus produce hippocampal theta rhythm in the urethane anesthetized rat

  1995cited by this paper
• Serotonergic and non-serotonergic projections from the raphe nuclei to the piriform cortex in the rat: a cholera toxin B subunit (CTb) and 5-HT immunohistochemical study.

  1995influential reference
• Branching serotonergic and non-serotonergic projections from caudal brainstem to the medial preoptic area and the lumbar spinal cord, in the rat.

  1995influential reference
• Projections of the dorsal raphe nucleus to the brainstem: PHA‐L analysis in the rat

  1994cited by this paper
• Injections of excitatory amino acid antagonists into the median raphe nucleus produce hippocampal theta rhythm in the urethane-anesthetized rat.

  1994cited by this paper
• Pharmacological suppression of the median raphe nucleus with serotonin1A agonists, 8-OH-DPAT and buspirone, produces hippocampal theta rhythm in the rat.

  1994cited by this paper
• Calretinin is present in non-pyramidal cells of the rat hippocampus--III. Their inputs from the median raphe and medial septal nuclei.

  1993cited by this paper
• Structure and function of the brain serotonin system.

  1992cited by this paper
• Convergence and segregation of septal and median raphe inputs onto different subsets of hippocampal inhibitory interneurons.

  1992cited by this paper
• GABAergic Interneurons are the Major Postsynaptic Targets of Median Raphe Afferents in the Rat Dentate Gyrus

  1992cited by this paper
• Modulation of synaptic plasticity in the dentate gyrus of the rat by electrical stimulation of the median raphe nucleus.

  1991cited by this paper
• Significant non-serotonergic raphe projection to the visual cortex of the rat. An immunohistochemical study combined with retrograde tracing.

  1991cited by this paper
• Distribution of two morphologically distinct subsets of serotoninergic axons in the cerebral cortex of the marmoset

  1990cited by this paper
• Serotonergic control of the hippocampus via local inhibitory interneurons.

  1990cited by this paper
• Anatomy of the Serotonergic System a

  1990cited by this paper
• Behavioral and biochemical evidence for a functional role of excitatory amino acids in the median raphe nucleus.

  1989cited by this paper
• Serotoninergic innervation of the cat cerebral cortex

  1988cited by this paper
• Autoradiographic analysis of ascending projections from the pontine and mesencephalic reticular formation and the median raphe nucleus in the rat

  1988cited by this paper
• Serotonergic and nonserotonergic projections from the rat interpeduncular nucleus to the septum, hippocampal formation and raphe: a combined immunocytochemical and fluorescent retrograde labelling study of neurons in the apical subnucleus.

  1988influential reference
• Dorsal raphe serotoninergic branching neurons projecting both to the lateral geniculate body and superior colliculus: A combined retrograde tracing–immunohistochemical study in the rat

  1988influential reference
• Evidence against serotonin involvement in the hyperactivity produced by injections of muscimol into the median raphe nucleus.

  1987cited by this paper
• Coexistence of galanin-like immunoreactivity with catecholamines, 5- hydroxytryptamine, GABA and neuropeptides in the rat CNS

  1986cited by this paper
• Electrolytic, but not 5,7-dihydroxytryptamine, lesions of the nucleus medianus raphe impair acquisition of a radial maze task.

  1985cited by this paper
• Identification of dopamine-containing cell bodies in the dorsal and median raphe nuclei of the rat brain using tyrosine hydroxylase immunochemistry.

  1985cited by this paper
• Organization of raphe-cortical projections in rat: a quantitative retrograde study.

  1984cited by this paper
• An analysis of neuronal elements within the median nucleus of the raphe that mediate lesion-induced increases in locomotor activity.

  1983cited by this paper
• Combined immunocytochemistry and autoradiographic retrograde axonal tracing for identification of transmitters of projection neurons.

  1983cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983influential reference
• Impaired radial maze performance in rats with electrolytic median raphe lesions.

  1983cited by this paper
• The distribution and origin of serotonin‐containing fibers in the septal area: A combined immunohistochemical and fluorescent retrograde tracing study in the rat

  1982influential reference
• Identification of serotonin and non-serotonin-containing neurons of the mid-brain raphe projecting to the entorhinal area and the hippocampal formation. A combined immunohistochemical and fluorescent retrograde tracing study in the rat brain.

  1982cited by this paper
• Bilateral serotonergic projections to the dorsal hippocampus of the rat: Simultaneous localization of 3H‐5HT and HRP after retrograde transport

  1981cited by this paper
• An analysis of ascending brain stem systems involved in hippocampal synchronization and desynchronization.

  1981cited by this paper
• Influence of raphe nuclei on neuronal transmission from perforant pathway through dentate gyrus.

  1980cited by this paper
• Retrograde demonstration of hippocampal afferents from the interpeduncular and reuniens nuclei.

  1979cited by this paper
• Effects of median raphe nucleus lesions on hippocampal EEG in the freely moving rat.

  1979cited by this paper
• The connections of the septal region in the rat

  1979cited by this paper
• An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat

  1978cited by this paper
• The role of a raphe serotonin system in the control of septal unit activity and hippocampal desynchronization.

  1978cited by this paper
• Open field activity and avoidance behavior following serotonin depletion: a comparison of the effects of parachlorophenylalanine and electrolytic midbrain raphe lesions.

  1978cited by this paper
• Activity, avoidance learning and regional 5-hydroxytryptamine following intra-brain stem 5,7-dihydroxytryptamine and electrolytic midbrain raphe lesions in the rat.

  1976cited by this paper
• Behavioral effects of selective midbrain raphe lesions in the rat.

  1975cited by this paper
• DYNAMIC RESPONSE OF CHEST WALL AND LUNG INJURIES IN RABBITS EXPOSED TO AIR SHOCK WAVES OF SHORT DURATION.

  1964cited by this paper
• EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

  1964cited by this paper

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  2017cites this paper
• Neurochemical differences between target-specific populations of rat dorsal raphe projection neurons.

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• Sodium oxybate treatment in narcolepsy and its effect on muscle tone.

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  2009cites this paper
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