Signaling to stomatal initiation and cell division

Stomata are two-celled valves that control epidermal pores whose opening and spacing optimizes shoot-atmosphere gas exchange. Arabidopsis stomatal formation involves at least one asymmetric division and one symmetric division. Stomatal formation and patterning are regulated by the frequency and placement of asymmetric divisions. This model system has already led to significant advances in developmental biology, such as the regulation of cell fate, division, differentiation, and patterning. Over the last 30 years, stomatal development has been found to be controlled by numerous intrinsic genetic and environmental factors. This mini review focuses on the signaling involved in stomatal initiation and in divisions in the cell lineage.

• Publication year

  2014

• Venue

  Frontiers in Plant Science

• Publication date

  2014-05-19

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3389/fpls.2014.00297PMID 25002867PMCID 4066587
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Auxin transport and activity regulate stomatal patterning and development

  2014cited by this paper
• New phenotypic characteristics of three tmm alleles in Arabidopsis thaliana

  2014cited by this paper
• Deep functional redundancy between FAMA and FOUR LIPS in stomatal development.

  2014cited by this paper
• Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis

  2014cited by this paper
• A new loss-of-function allele 28y reveals a role of ARGONAUTE1 in limiting asymmetric division of stomatal lineage ground cell.

  2014cited by this paper
• What Causes Opposing Actions of Brassinosteroids on Stomatal Development?1

  2013cited by this paper
• ABA inhibits entry into stomatal-lineage development in Arabidopsis leaves.

  2013cited by this paper
• FOUR LIPS and MYB88 conditionally restrict the G1/S transition during stomatal formation

  2013influential reference
• Brassinosteroid-regulated GSK3/Shaggy-like Kinases Phosphorylate Mitogen-activated Protein (MAP) Kinase Kinases, Which Control Stomata Development in Arabidopsis thaliana*

  2013cited by this paper
• Sterols are required for cell-fate commitment and maintenance of the stomatal lineage in Arabidopsis.

  2013cited by this paper
• On fate and flexibility in stomatal development.

  2012cited by this paper
• Brassinosteroids tailor stomatal production to different environments.

  2012cited by this paper
• SPEECHLESS integrates brassinosteroid and stomata signalling pathways

  2012cited by this paper
• Mechanisms of stomatal development.

  2012cited by this paper
• The microRNA pathway genes AGO1, HEN1 and HYL1 participate in leaf proximal-distal, venation and stomatal patterning in Arabidopsis.

  2012cited by this paper
• GSK3-Like Kinases Integrate Brassinosteroid Signaling and Stomatal Development

  2012cited by this paper
• RETINOBLASTOMA RELATED1 Regulates Asymmetric Cell Divisions in Arabidopsis[C][W][OA]

  2012influential reference
• Stomatal development: a plant's perspective on cell polarity, cell fate transitions and intercellular communication

  2012cited by this paper
• Emerging roles of RETINOBLASTOMA-RELATED proteins in evolution and plant development.

  2012cited by this paper
• Direct interaction of ligand-receptor pairs specifying stomatal patterning.

  2012influential reference
• Genetic framework of cyclin-dependent kinase function in Arabidopsis.

  2012cited by this paper
• Relationship between brassinosteroids and genes controlling stomatal production in the Arabidopsis hypocotyl.

  2012cited by this paper
• Mix-and-match: ligand-receptor pairs in stomatal development and beyond.

  2012cited by this paper
• Developmental regulation of CYCA2s contributes to tissue‐specific proliferation in Arabidopsis

  2011cited by this paper
• Generation of Spatial Patterns Through Cell Polarity Switching

  2011cited by this paper
• Molecular Profiling of Stomatal Meristemoids Reveals New Component of Asymmetric Cell Division and Commonalities among Stem Cell Populations in Arabidopsis[C][W][OA]

  2011cited by this paper
• Differentiation of Arabidopsis Guard Cells: Analysis of the Networks Incorporating the Basic Helix-Loop-Helix Transcription Factor, FAMA1[C][W][OA]

  2011cited by this paper
• Brassinosteroid regulates stomatal development by GSK3-mediated inhibition of a MAPK pathway

  2011cited by this paper
• Generation of Signaling Specificity in Arabidopsis by Spatially Restricted Buffering of Ligand–Receptor Interactions[C][W][OA]

  2011cited by this paper
• The signalling peptide EPFL9 is a positive regulator of stomatal development.

  2010cited by this paper
• Stomagen positively regulates stomatal density in Arabidopsis

  2010cited by this paper
• Regional specification of stomatal production by the putative ligand CHALLAH

  2010cited by this paper
• Arabidopsis RETINOBLASTOMA-RELATED Is Required for Stem Cell Maintenance, Cell Differentiation, and Lateral Organ Production[W][OA]

  2010influential reference
• Regulation of Cell Proliferation in the Stomatal Lineage by the Arabidopsis MYB FOUR LIPS via Direct Targeting of Core Cell Cycle Genes[W]

  2010influential reference
• Stomatal density is controlled by a mesophyll-derived signaling molecule.

  2010influential reference
• Structural and Functional Study of Yer067w, a New Protein Involved in Yeast Metabolism Control and Drug Resistance

  2010cited by this paper
• Epidermal cell density is autoregulated via a secretory peptide, EPIDERMAL PATTERNING FACTOR 2 in Arabidopsis leaves.

  2009cited by this paper
• CDKB1;1 Forms a Functional Complex with CYCA2;3 to Suppress Endocycle Onset1[W][OA]

  2009cited by this paper
• Faculty Opinions recommendation of Cryptochromes, phytochromes, and COP1 regulate light-controlled stomatal development in Arabidopsis.

  2009cited by this paper
• The signaling peptide EPF2 controls asymmetric cell divisions during stomatal development.

  2009cited by this paper
• Cryptochromes, Phytochromes, and COP1 Regulate Light-Controlled Stomatal Development in Arabidopsis[W]

  2009cited by this paper
• Novel and Expanded Roles for MAPK Signaling in Arabidopsis Stomatal Cell Fate Revealed by Cell Type–Specific Manipulations[C][W]

  2009cited by this paper
• BASL controls asymmetric cell division in Arabidopsis.

  2009cited by this paper
• SCREAM/ICE1 and SCREAM2 Specify Three Cell-State Transitional Steps Leading to Arabidopsis Stomatal Differentiation[W][OA]

  2008cited by this paper
• TOO MANY MOUTHS promotes cell fate progression in stomatal development of Arabidopsis stems

  2008cited by this paper
• Arabidopsis Stomatal Initiation Is Controlled by MAPK-Mediated Regulation of the bHLH SPEECHLESS

  2008cited by this paper
• Reference Intervals in Healthy Adult Ugandan Blood Donors and Their Impact on Conducting International Vaccine Trials

  2008cited by this paper
• Transcription factor control of asymmetric cell divisions that establish the stomatal lineage

  2007cited by this paper
• MicroRNA-Mediated Regulation of Stomatal Development in Arabidopsis[W][OA]

  2007cited by this paper
• Termination of asymmetric cell division and differentiation of stomata

  2007cited by this paper
• The secretory peptide gene EPF1 enforces the stomatal one-cell-spacing rule.

  2007cited by this paper
• Stomatal development.

  2007influential reference
• Stomatal Development and Patterning Are Regulated by Environmentally Responsive Mitogen-Activated Protein Kinases in Arabidopsis[W]

  2007cited by this paper
• Arabidopsis FAMA Controls the Final Proliferation/Differentiation Switch during Stomatal Development[W][OA]

  2006cited by this paper
• Cell Type-Specific Role of the Retinoblastoma/E2F Pathway during Arabidopsis Leaf Development1

  2005cited by this paper
• Stomatal Patterning and Differentiation by Synergistic Interactions of Receptor Kinases

  2005cited by this paper
• The Arabidopsis R2R3 MYB Proteins FOUR LIPS and MYB88 Restrict Divisions Late in the Stomatal Cell Lineage

  2005cited by this paper
• Stomatal Development and Pattern Controlled by a MAPKK Kinase

  2004cited by this paper
• B1-Type Cyclin-Dependent Kinases Are Essential for the Formation of Stomatal Complexes in Arabidopsis thaliana

  2004cited by this paper
• Growth and stomata development of Arabidopsis hypocotyls are controlled by gibberellins and modulated by ethylene and auxins.

  2003cited by this paper
• Control of Stomatal Distribution on the Arabidopsis Leaf Surface

  2002cited by this paper
• Stomatal Development in Arabidopsis

  2002influential reference
• Divergent regulation of stomatal initiation and patterning in organ and suborgan regions of the Arabidopsis mutants too many mouths and four lips

  1998cited by this paper
• The too many mouths and four lips mutations affect stomatal production in Arabidopsis.

  1995influential reference
• Control of Stomatal Distribution on the Arabidopsis Leaf Surface

  year unknowncited by this paper

• Nitric oxide controls stomatal development and stress responses by inhibiting MPK6 phosphorylation via S-nitrosylation in Arabidopsis.

  2025cites this paper
• ABA-mediated regulation of PME12 influences stomatal density, pore aperture, and heat stress response in Arabidopsis thaliana

  2025cites this paper
• Deciphering Auxin-Regulated Stomatal Development: Novel Insights into Phytochrome-Interacting Factors, FOUR LIPS, and SNF1-Related Kinase Interactions.

  2025cites this paper
• Cytoskeletal control of development and environmental adaptation in plants.

  2025cites this paper
• Regulation of stomatal development by epidermal, subepidermal and long-distance signals

  2024cites this paper
• Taxonomic implications of normal and abnormal stomatal complexes in Indigofera L. (Indigofereae, Faboideae, Fabaceae)

  2024cites this paper
• Novel Roles of SPATULA in the Control of Stomata and Trichome Number, and Anthocyanin Biosynthesis

  2023cites this paper
• Guard Cell-Specific Pectin METHYLESTERASE53 Is Required for Abscisic Acid-Mediated Stomatal Function and Heat Response in Arabidopsis

  2022cites this paper
• Emerging roles of protein phosphorylation in regulation of stomatal development.

  2022cites this paper
• Identification of the genetic locus associated with crinkled leaf phenotype in a soybean (Glycine max L.) mutant by BSA-Seq technology

  2022cites this paper
• Analyses and identifications of quantitative trait loci and candidate genes controlling mesocotyl elongation in rice

  2022cites this paper
• Water‐related innovations in land plants evolved by different patterns of gene cooption and novelty

  2022cites this paper
• Methyl jasmonate and Ag+ as effective elicitors for enhancement of phenolic acids contents in Salvia officinalis and Salvia verticillata, as two traditional medicinal plants

  2021cites this paper
• The DME demethylase regulates sporophyte gene expression, cell proliferation, differentiation, and meristem resurrection

  2021cites this paper
• SPEECHLESS and MUTE Mediate Feedback Regulation of Signal Transduction during Stomatal Development

  2021cites this paper
• MdHB-7 Regulates Water Use Efficiency in Transgenic Apple (Malus domestica) Under Long-Term Moderate Water Deficit

  2021cites this paper
• Influence of Environmental Factors Light, CO2, Temperature, and Relative Humidity on Stomatal Opening and Development: A Review

  2020cites this paper
• YODA-HSP90 module regulates phosphorylation-dependent inactivation of SPEECHLESS to control stomatal development under acute heat stress in Arabidopsis.

  2020cites this paper
• Regulation of stomatal development by stomatal lineage miRNAs

  2020cites this paper
• HD‐ZIP IV gene Roc8 regulates the size of bulliform cells and lignin content in rice

  2020cites this paper
• RNA polymerase II associated proteins regulate stomatal development through directly interacting with the stomatal transcription factors in Arabidopsis thaliana.

  2020cites this paper
• Investigation of photosynthetic effects, carbohydrate and starch content in cress (Lepidium sativum) under the influence of blue and red spectrum

  2020cites this paper
• The effect of light quality on the expression of stomatal development genes of maize

  2019cites this paper
• The effect of light quality on the expression of stomatal development genes of maize

  2019cites this paper
• Modulation of auxin signalling through DIAGETROPICA and ENTIRE differentially affects tomato plant growth via changes in photosynthetic and mitochondrial metabolism.

  2018cites this paper
• Stomatal development: focusing on the grasses.

  2018cites this paper
• A2-type cyclin is required for the asymmetric entry division in rice stomatal development

  2018cites this paper
• Mitogen-Activated Protein Kinase Cascades in Plant Hormone Signaling

  2018cites this paper
• Transcription Factors and Hormone‐Mediated Mechanisms Regulate Stomata Development and Responses Under Abiotic Stresses: An Overview

  2017cites this paper
• Too many faces for TOO MANY MOUTHS?

  2016cites this paper
• Hormonal regulation of drought stress in plants

  2016cites this paper
• Regulation of stomatal morphogenesis and lateral root development in Arabidopsis thaliana by the leucine-rich repeat receptor-like kinase MUSTACHES

  2016influential citation
• Organ-specific effects of brassinosteroids on stomatal production coordinate with the action of Too Many Mouths.

  2015cites this paper
• Peptydy bogate w cysteinę

  2015cites this paper
• Phosphorylation of Serine 186 of bHLH Transcription Factor SPEECHLESS Promotes Stomatal Development in Arabidopsis.

  2015cites this paper
• Regulation of cell fate determination in plants

  2014cites this paper