We studied the effects of four soluble surfactants on DPPC monolayers to elucidate the action of these membrane perturbants. The presence of nonionic N-9 and amphoteric C31G strongly affected the pure DPPC isotherm, while anionic SDS and cationic DTAB had little effect. The impact of surfactant on DPPC domain shape in the liquid condensed-liquid expanded coexistence region showed the opposite result. Neutral surfactants had minimal effect on the shape of DPPC domains; charged surfactants, on the other hand, induced a new shape transition at high surface pressures previously unreported for DPPC domains. All of these results are discussed with particular attention given to electrostatic effects at the interface.
Interaction of DPPC monolayers with soluble surfactants: electrostatic effects of membrane perturbants.
C. W. McConlogue,D. Malamud,T. Vanderlick
Published 1998 in Biochimica et Biophysica Acta
ABSTRACT
PUBLICATION RECORD
- Publication year
1998
- Venue
Biochimica et Biophysica Acta
- Publication date
1998-06-24
- Fields of study
Medicine, Chemistry
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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