Design and evaluation of a multiplex vesicular rash PCR for the detection of varicella zoster virus and herpes simplex virus

Varicella zoster virus (VZV) typically infects the skin leading to chickenpox (varicella) and herpes zoster whereas herpes simplex virus 1 and 2 (HSV-1/-2) often affect the mucosa forming herpes labialis and genital herpes. However, in eczema herpeticum and herpes gladiatorum, HSV infections occur on the skin. The cutaneous infections with VZV or HSV often present similar clinical manifestations causing trouble in differentiation.

• Publication year

  2021

• Venue

  Journal of the European Academy of Dermatology and Venereology

• Publication date

  2021-03-02

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/jdv.17198PMID 33655562
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Detection of Herpes Simplex Virus and Varicella-Zoster Virus by Traditional and Multiplex Molecular Methods

  2018cited by this paper
• Development of a multiplex real-time PCR for the simultaneous detection of herpes simplex and varicella zoster viruses in cerebrospinal fluid and lesion swab specimens.

  2016cited by this paper
• A multicenter prospective trial to asses a new real-time polymerase chain reaction for detection of Treponema pallidum, herpes simplex-1/2 and Haemophilus ducreyi in genital, anal and oropharyngeal ulcers.

  2014cited by this paper
• Development and Clinical Validation of a Multiplex Real-time PCR Assay for Herpes Simplex and Varicella Zoster Virus

  2013cited by this paper
• Zosteriform herpes simplex.

  2008cited by this paper
• Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative.

  2007cited by this paper
• Differentiation of herpes simplex virus types 1 and 2 in clinical samples by a real‐time taqman PCR assay

  2005cited by this paper
• Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. The Standards for Reporting of Diagnostic Accuracy Group.

  2003cited by this paper
• Major histocompatibility complex class II‐restricted presentation of a cytosolic antigen by autophagy

  2003cited by this paper
• Varicella-zoster virus: atypical presentations and unusual complications.

  2002cited by this paper
• Herpes simplex virus infections

  1984cited by this paper
• Zosteriform herpes simplex.

  1976cited by this paper

• Structure-optimized iridium complex coordination-functionalized ZIF-8-based nanoemitters with HEPES as novel efficient and eco-friendly ECL system for multiplex assays of HSV and VZV

  2024cites this paper
• Profiling of the Conjunctival Bacterial Microbiota Reveals the Feasibility of Utilizing a Microbiome-Based Machine Learning Model to Differentially Diagnose Microbial Keratitis and the Core Components of the Conjunctival Bacterial Interaction Network

  2022cites this paper