T cell development and function in CrkL‐deficient mice

No abstract is available for this paper.

• Publication year

  2003

• Venue

  European Journal of Immunology

• Publication date

  2003-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/eji.200324294PMID 14515252
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl

  2002cited by this paper
• -Terminal Kinase (JNK)1 and JNK2 Have Distinct Roles in CD8 T Cell Activation

  2002cited by this paper
• c-Jun NH2-Terminal Kinase (JNK)1 and JNK2 Have Distinct Roles in CD8+ T Cell Activation

  2002cited by this paper
• c-Jun NH 2-Terminal Kinase ( JNK ) 1 and JNK 2 Have Distinct Roles in CD 8 T Cell Activation

  2002cited by this paper
• CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk.

  2001cited by this paper
• The Stress Kinase Mitogen-Activated Protein Kinase Kinase (Mkk)7 Is a Negative Regulator of Antigen Receptor and Growth Factor Receptor–Induced Proliferation in Hematopoietic Cells

  2001cited by this paper
• DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1

  2001cited by this paper
• L-selectin tyrosine phosphorylates cbl and induces association of tyrosine-phosphorylated cbl with crkl and grb2.

  2001cited by this paper
• Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome

  2001cited by this paper
• CD28 Is Not Required for c-Jun N-Terminal Kinase Activation in T Cells1

  2001cited by this paper
• C-Jun Nh2-Terminal Kinase (Jnk)1 and Jnk2 Have Similar and Stage-Dependent Roles in Regulating T Cell Apoptosis and Proliferation

  2001cited by this paper
• Tbx1 haploinsufficiency in the DiGeorge syndrome region causes aortic arch defects in mice

  2001cited by this paper
• Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL-expressing cells.

  2001cited by this paper
• Engagement of the CrkL adaptor in interferon α signalling in BCR–ABL‐expressing cells

  2001cited by this paper
• CrkL Is Recruited through Its SH2 Domain to the Erythropoietin Receptor and Plays a Role in Lyn-mediated Receptor Signaling*

  2001cited by this paper
• Engagement of the CrkL Adapter in Interleukin-5 Signaling in Eosinophils*

  2000cited by this paper
• IFN-γ Activates the C3G/Rap1 Signaling Pathway1

  2000cited by this paper
• T cell receptor repertoire and function in patients with DiGeorge syndrome and velocardiofacial syndrome

  2000cited by this paper
• IFN-gamma activates the C3G/Rap1 signaling pathway.

  2000cited by this paper
• Signaling of Hepatocyte Growth Factor/Scatter Factor (HGF) to the Small GTPase Rap1 via the Large Docking Protein Gab1 and the Adapter Protein CRKL*

  2000cited by this paper
• CrkL Mediates Ras-dependent Activation of the Raf/ERK Pathway through the Guanine Nucleotide Exchange Factor C3G in Hematopoietic Cells Stimulated with Erythropoietin or Interleukin-3*

  1999cited by this paper
• The Adapter Protein Crkl Links Cbl to C3G after Integrin Ligation and Enhances Cell Migration*

  1999cited by this paper
• Interaction of Hematopoietic Progenitor Kinase 1 with Adapter Proteins Crk and CrkL Leads to Synergistic Activation of c-Jun N-Terminal Kinase

  1999cited by this paper
• CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors.

  1999cited by this paper
• CrkL activates integrin-mediated hematopoietic cell adhesion through the guanine nucleotide exchange factor C3G.

  1999cited by this paper
• Activation of a CrkL-Stat5 Signaling Complex by Type I Interferons*

  1999cited by this paper
• Costimulation through CD28 Suppresses T Cell Receptor-dependent Activation of the Ras-like Small GTPase Rap1 in Human T Lymphocytes*

  1998cited by this paper
• Interplay of the Proto-oncogene Proteins CrkL and CrkII in Insulin-like Growth Factor-I Receptor-mediated Signal Transduction*

  1998cited by this paper
• Physiological signals and oncogenesis mediated through Crk family adapter proteins

  1998cited by this paper
• Interleukin-2 Stimulation Induces Tyrosine Phosphorylation of p120-Cbl and CrkL and Formation of Multimolecular Signaling Complexes in T Lymphocytes and Natural Killer Cells*

  1998cited by this paper
• Role of the adapter protein CRKL in signal transduction of normal hematopoietic and BCR/ABL-transformed cells

  1998cited by this paper
• B7.1 is a quantitatively stronger costimulus than B7.2 in the activation of naive CD8+ TCR-transgenic T cells.

  1998cited by this paper
• Development of highly selective SH3 binding peptides for Crk and CRKL which disrupt Crk-complexes with DOCK180, SoS and C3G

  1998cited by this paper
• SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development.

  1998cited by this paper
• Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1.

  1997cited by this paper
• Differential Signaling after β1 Integrin Ligation Is Mediated Through Binding of CRKL to p120 CBL and p110 HEF1 *

  1997cited by this paper
• Erythropoietin and IL-3 induce tyrosine phosphorylation of CrkL and its association with Shc, SHP-2, and Cbl in hematopoietic cells.

  1997cited by this paper
• Steel Factor Induces Tyrosine Phosphorylation of CRKL and Binding of CRKL to a Complex Containing c-Kit, Phosphatidylinositol 3-Kinase, and p120CBL*

  1997cited by this paper
• T cell clonal anergy.

  1997cited by this paper
• Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells.

  1997cited by this paper
• In Vivo Regulation of CrkII and CrkL Proto-oncogenes in the Uterus by Insulin-like Growth Factor-I

  1997cited by this paper
• Enhancement of Guanine-Nucleotide Exchange Activity of C3G for Rap1 by the Expression of Crk, CrkL, and Grb2*

  1997cited by this paper
• Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.

  1997cited by this paper
• Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways

  1996cited by this paper
• Tyrosine Phosphorylation of Cbl upon Epidermal Growth Factor (EGF) Stimulation and Its Association with EGF Receptor and Downstream Signaling Proteins*

  1996cited by this paper
• B Cell Antigen Receptor Signaling Induces the Formation of Complexes Containing the Crk Adapter Proteins*

  1996cited by this paper
• Stimulation through the T Cell Receptor Induces Cbl Association with Crk Proteins and the Guanine Nucleotide Exchange Protein C3G (*)

  1996cited by this paper
• Control of T lymphocyte signal transduction through clonal anergy

  1996cited by this paper
• Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

  1996cited by this paper
• Tyrosine phosphorylation of murine Crkl.

  1995cited by this paper
• T cell clonal anergy.

  1994cited by this paper
• Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia.

  1994cited by this paper
• Identification of CRKL as the constitutively phosphorylated 39-kD tyrosine phosphoprotein in chronic myelogenous leukemia cells.

  1994cited by this paper
• CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells

  1994cited by this paper
• Isolation and chromosomal localization of CRKL, a human crk-like gene.

  1993cited by this paper
• Two species of human CRK cDNA encode proteins with distinct biological activities

  1992cited by this paper
• Current protocols in immunology

  1991cited by this paper
• Regulation of T‐Cell Activation; Differences among T‐Cell Subsets

  1989cited by this paper
• Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

  1988cited by this paper
• Mice P190 Transgenic Bcr/abl Crkl Enhances Leukemogenesis in Updated Version Cited Articles Citing Articles E-mail Alerts Crkl Enhances Leukemogenesis in Bcr/abl P190 Transgenic Mice 1

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