Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Medical and Biological Engineering and Computing

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1007/s11517-008-0383-2PMID 18712425
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Activation of MEK-ERK by heregulin-beta1 promotes the development of cardiomyocytes derived from ES cells.

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• GATA Factors Lie Upstream of Nkx 2.5 in the Transcriptional Regulatory Cascade That Effects Cardiogenesis

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• Identification and characterization of embryonic stem cell‐derived pacemaker and atrial cardiomyocytes

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• Differentiation of embryonic stem cells into cardiac myocytes

  2002cited by this paper
• The Transcription Factors GATA4 and dHAND Physically Interact to Synergistically Activate Cardiac Gene Expression through a p300-dependent Mechanism*

  2002cited by this paper
• Differentiation of Pluripotent Embryonic Stem Cells Into Cardiomyocytes

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• Cellular function of phosphoinositide 3-kinases: Implications for development, immunity, homeostasis, and cancer

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• Glycogen synthase kinase 3beta regulates GATA4 in cardiac myocytes.

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• Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta.

  2001cited by this paper
• p300 Functions as a Coactivator of Transcription Factor GATA-4*

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• Selection of ventricular‐like cardiomyocytes from ES cells in vitro

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• Role of reactive oxygen species and phosphatidylinositol 3‐kinase in cardiomyocyte differentiation of embryonic stem cells

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• Phosphoinositide 3-Kinase Induces the Transcriptional Activity of MEF2 Proteins during Muscle Differentiation*

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• Inhibition of phosphatidylinositol-3-kinase blocks development of functional embryonic cardiomyocytes.

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• Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts.

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• Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer.

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  1995cited by this paper
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  1994cited by this paper
• Transition in cardiac contractile sensitivity to calcium during the in vitro differentiation of mouse embryonic stem cells

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• Receptor protein-tyrosine kinases and their signal transduction pathways.

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• Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium.

  1994cited by this paper
• Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants.

  1993influential reference
• Authors' correction: Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants

  1993cited by this paper

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• Neuregulin-1β induces proliferation, survival and paracrine signaling in normal human cardiac ventricular fibroblasts.

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• Probing early heart development to instruct stem cell differentiation strategies

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• Expression and Function of the Epidermal Growth Factor Receptor in Physiology and Disease.

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• Human fetal cardiac progenitors: The role of stem cells and progenitors in the fetal and adult heart.

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• The Roles of Neuregulin-1 in Cardiac Development, Homeostasis, and Disease

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• Mesenchymal stem cells from rat olfactory bulbs can differentiate into cells with cardiomyocyte characteristics

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• Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors.

  2014cites this paper
• Effect of NRG-1/ErbB Signaling Intervention on the Differentiation of Bone Marrow Stromal Cells Into Sinus Node–like Cells

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• Molecular Determinants of Cardiac Development

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• The developing role of Neuregulin1 in cardiac regenerative stem cell therapy.

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• Vascular Repair at the Interface of the Endothelium: The Roles of Protease-Activated Receptors and Neuregulin-1

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• Time-dependent regulation of neuregulin-1β/ErbB/ERK pathways in cardiac differentiation of mouse embryonic stem cells

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