An RNAi screen in the Caenorhabditis elegans gonad identifies new regulators for centrosome behavior in oogenesis. LIN-41 is found to be a promoter for centrosome elimination in oocytes. Moreover, LIN-41 depletion results in ectopic activation of centrosomes and abnormal chromosome behavior in female meiosis.
LIN-41 inactivation leads to delayed centrosome elimination and abnormal chromosome behavior during female meiosis in Caenorhabditis elegans
R. Matsuura,Tomoko Ashikawa,Yuka Nozaki,Daiju Kitagawa
Published 2016 in Molecular Biology of the Cell
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- Publication year
2016
- Venue
Molecular Biology of the Cell
- Publication date
2016-03-01
- Fields of study
Biology, Medicine
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- Source metadata
Semantic Scholar, PubMed
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