Novel Strategies for Healthy Brain Aging

Devin Wahl,A. Cavalier,T. LaRocca

Published 2021 in Exercise and sport sciences reviews

ABSTRACT

This review examines the influence of exercise, pharmaceutical compounds, and select interventions on the hallmarks of brain aging. One of the best strategies for healthy brain aging is regular aerobic exercise. Commonly studied “anti-aging” compounds may mimic some effects of exercise on the brain, but novel approaches that target energy-sensing pathways similar to exercise probably will be more effective in this context. We review evidence in support of this hypothesis by focusing on biological hallmarks of brain aging.

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