Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Cellular Physiology

• Publication date

  2008-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/jcp.21482PMID 18498122PMCID PMC3992714
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Canonical and non‐canonical wnts differentially affect the development potential of primary isolate of human bone marrow mesenchymal stem cells

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• Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases.

  2006cited by this paper
• Regulation of bone mass by Wnt signaling.

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• Developmental stage-specific biphasic roles of Wnt/β-catenin signaling in cardiomyogenesis and hematopoiesis

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• Wnt signalling in osteoblasts regulates expression of the receptor activator of NFκB ligand and inhibits osteoclastogenesis in vitro

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• The Wnt Co-receptor LRP5 Is Essential for Skeletal Mechanotransduction but Not for the Anabolic Bone Response to Parathyroid Hormone Treatment*

  2006cited by this paper
• Differential expression of WNTs and FRPs in the synovium of rheumatoid arthritis and osteoarthritis.

  2006cited by this paper
• SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor

  2005cited by this paper
• Wnt signaling in disease and in development

  2005influential reference
• Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer.

  2005cited by this paper
• Essential role of beta-catenin in postnatal bone acquisition.

  2005cited by this paper
• Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development

  2005cited by this paper
• Organization of transcriptional regulatory machinery in osteoclast nuclei: Compartmentalization of Runx1

  2005cited by this paper
• Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.

  2005cited by this paper
• Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation

  2005cited by this paper
• The Wnt antagonist secreted frizzled‐related protein‐1 controls osteoblast and osteocyte apoptosis

  2005cited by this paper
• Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression*

  2005cited by this paper
• Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis.

  2005cited by this paper
• Essential Role of β-Catenin in Postnatal Bone Acquisition*

  2005cited by this paper
• Secreted Frizzled‐Related Protein‐1 Inhibits RANKL‐Dependent Osteoclast Formation

  2004cited by this paper
• Primary mouse embryonic fibroblasts: A model of mesenchymal cartilage formation

  2004cited by this paper
• LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: Arrows point the way

  2004cited by this paper
• Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers

  2004cited by this paper
• The WNT/calcium pathway: biochemical mediators, tools and future requirements.

  2004cited by this paper
• Wnt signaling in the vasculature

  2004cited by this paper
• The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice.

  2004cited by this paper
• FrzA/sFRP-1, a secreted antagonist of the Wnt-Frizzled pathway, controls vascular cell proliferation in vitro and in vivo.

  2004influential reference
• LDL receptor-related protein LRP6 regulates proliferation and survival through the Wnt cascade in vascular smooth muscle cells.

  2004cited by this paper
• Evaluation of SFRP1 as a candidate for human retinal dystrophies.

  2004cited by this paper
• Manipulating hematopoietic stem cell amplification with Wnt

  2003influential reference
• A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling.

  2003cited by this paper
• Secreted antagonists of the Wnt signalling pathway

  2003influential reference
• A role for Wnt signalling in self-renewal of haematopoietic stem cells

  2003influential reference
• Wnt Signaling, Ca2+, and Cyclic GMP: Visualizing Frizzled Functions

  2003cited by this paper
• A Second Canon

  2003cited by this paper
• A molecular fingerprint for medulloblastoma.

  2003cited by this paper
• Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina

  2003cited by this paper
• Wnt proteins are lipid-modified and can act as stem cell growth factors

  2003influential reference
• The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis.

  2002cited by this paper
• Wnt signalling during limb development.

  2002cited by this paper
• Comprehensive Microarray Analysis of Bone Morphogenetic Protein 2‐Induced Osteoblast Differentiation Resulting in the Identification of Novel Markers for Bone Development

  2002cited by this paper
• Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation

  2002cited by this paper
• Differential gene expression of sFRP-1 and apoptosis in pulmonary emphysema.

  2002cited by this paper
• Secreted Frizzled-related proteins can regulate metanephric development.

  2001cited by this paper
• Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton.

  2001cited by this paper
• Antagonistic regulation of convergent extension movements in Xenopus by Wnt/beta-catenin and Wnt/Ca2+ signaling.

  2001cited by this paper
• Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon.

  2001cited by this paper
• Place- and time-dependent expression of mouse sFRP-1 during development of the cerebral neocortex.

  2001cited by this paper
• Sfrp-1 and sfrp-2 are expressed in overlapping and distinct domains during chick development.

  2000cited by this paper
• Expression pattern of mouse sFRP-1 and mWnt-8 gene during heart morphogenesis.

  2000cited by this paper
• Regulation of chondrocyte differentiation by Cbfa1.

  1999cited by this paper
• Identification and cloning of a secreted protein related to the cysteine-rich domain of frizzled. Evidence for a role in endothelial cell growth control.

  1999cited by this paper
• Involvement of Frzb-1 in mesenchymal condensation and cartilage differentiation in the chick limb bud.

  1999cited by this paper
• A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling.

  1999cited by this paper
• Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family.

  1998influential reference
• Expression pattern of two Frizzled‐related genes, Frzb‐1 and Sfrp‐1, during mouse embryogenesis suggests a role for modulating action of Wnt family members

  1998cited by this paper
• sFRP‐2 is a target of the Wnt‐4 signaling pathway in the developing metanephric kidney

  1998cited by this paper
• SARPs: a family of secreted apoptosis-related proteins.

  1997cited by this paper
• Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia.

  1997influential reference
• Functional interaction of β-catenin with the transcription factor LEF-1

  1996cited by this paper
• Functional interaction of beta-catenin with the transcription factor LEF-1.

  1996cited by this paper
• Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes.

  1993cited by this paper
• Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene

  1992cited by this paper
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  1991cited by this paper

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  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
• Inhibition of bone formation in rats by aluminum exposure via Wnt/β-catenin pathway.

  2017cites this paper
• Origin and Function of the Renal Stroma in Health and Disease.

  2017cites this paper
• Stromal Cells Control Nephron Formation in a Hedgehog- Dependent Manner

  2017cites this paper
• Control of Lineage Decisions in the Embryonic Kidney by Hedgehog Signalling

  2016cites this paper
• Investigation of the effects of estrogen on skeletal gene expression during zebrafish larval head development

  2016cites this paper
• Multi-lineage differentiation of mesenchymal stem cells - To Wnt, or not Wnt.

  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
• Reduced expression of Sfrp1 during chondrogenesis and in articular chondrocytes correlates with osteoarthritis in STR/ort mice.

  2013cites this paper
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• Wnt Antagonist SFRP1 Functions as a Secreted Mediator of Senescence

  2012cites this paper
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• The Wnt/beta-catenin pathway in adrenocortical development and cancer.

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• Wnt Signaling in Bone Development

  2010cites this paper
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  2010cites this paper
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  2010cites this paper
• The advantages and disadvantages of sfrp1 and sfrp2 expression in pathological events.

  2010cites this paper
• Novel regulators of Fgf23 expression and mineralization in Hyp bone.

  2009cites this paper
• Wnt signaling controls the fate of mesenchymal stem cells.

  2009cites this paper
• Secreted frizzled related protein 1 is a target to improve fracture healing

  2009cites this paper
• Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.

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  2009cites this paper
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