A simple and rapid HPLC-DAD method for simultaneously monitoring the accumulation of alkaloids and precursors in different parts and different developmental stages of Catharanthus roseus plants.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

• Publication date

  2016-03-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.jchromb.2016.01.034PMID 26854826
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Solid-phase extraction of S-(-)-amlodipine from plasma with a uniformly sized molecularly imprinted polymer

  2012cited by this paper
• A new strategy for quality control and qualitative analysis of Yinhuang preparations by HPLC-DAD-MS/MS

  2012cited by this paper
• Simultaneous Quantification of Four Indole Alkaloids in Catharanthus roseus Cell Line C20hi by UPLC-MS

  2011cited by this paper
• Simple and reproducible HPLC-DAD-ESI-MS/MS analysis of alkaloids in Catharanthus roseus roots.

  2010cited by this paper
• Potential Role of Sugar Transporters in Cancer and Their Relationship with Anticancer Therapy

  2010cited by this paper
• Antidiabetic Activity of Vinca rosea Extracts in Alloxan-Induced Diabetic Rats

  2010cited by this paper
• The Leaf Epidermome of Catharanthus roseus Reveals Its Biochemical Specialization[W][OA]

  2008cited by this paper
• Manipulating indole alkaloid production by Catharanthus roseus cell cultures in bioreactors: from biochemical processing to metabolic engineering

  2007cited by this paper
• Analysis of Catharanthus roseus alkaloids by HPLC

  2007cited by this paper
• Strategies for the genetic modification of the medicinal plant Catharanthus roseus (L.) G. Don

  2007cited by this paper
• Transcriptome analysis in Catharanthus roseus leaves and roots for comparative terpenoid indole alkaloid profiles.

  2006cited by this paper
• Methyljasmonate accelerates catabolism of monoterpenoid indole alkaloids in Catharanthus roseus during leaf processing.

  2005cited by this paper
• Testing the optimal defense theory and the growth-differentiation balance hypothesis in Arabidopsis thaliana

  2005cited by this paper
• Rapid identification of vinca alkaloids by direct-injection electrospray ionisation tandem mass spectrometry and confirmation by high-performance liquid chromatography-mass spectrometry.

  2005cited by this paper
• Metabolic Discrimination of Catharanthus roseus Leaves Infected by Phytoplasma Using 1H-NMR Spectroscopy and Multivariate Data Analysis1

  2004cited by this paper
• Metabolic engineering of the indole pathway in Catharanthus roseus hairy roots and increased accumulation of tryptamine and serpentine.

  2004cited by this paper
• The Catharanthus alkaloids: pharmacognosy and biotechnology.

  2004cited by this paper
• Engineering the plant cell factory for secondary metabolite production

  2004cited by this paper
• Validation of high-performance liquid chromatography methods for pharmaceutical analysis. Understanding the differences and similarities between validation requirements of the US Food and Drug Administration, the US Pharmacopeia and the International Conference on Harmonization.

  2003influential reference
• Jasmonate-induced epoxidation of tabersonine by a cytochrome P-450 in hairy root cultures of Catharanthus roseus.

  2003cited by this paper
• Engineering secondary metabolite production in plants.

  2002cited by this paper
• Effect of precursor feeding on alkaloid accumulation by a strictosidine synthase over-expressing transgenic cell line S1 of Catharanthus roseus

  2002cited by this paper
• Screening of Catharanthus roseus secondary metabolites by high-performance liquid chromatography.

  2002influential reference
• The expanding universe of alkaloid biosynthesis.

  2001cited by this paper
• Molecular and biochemical analysis of a Madagascar periwinkle root-specific minovincinine-19-hydroxy-O-acetyltransferase.

  2001cited by this paper
• Terpenoid indole alkaloid profile changes in Catharanthus pusillus during development.

  2001cited by this paper
• Effects of alkaloid precursor feeding and elicitation on the accumulation of secologanin in a Catharanthus roseus cell suspension culture

  1999cited by this paper
• Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development

  1998cited by this paper
• A New Structural Class of Bisindole Alkaloids from the Seeds of Catharanthus roseus: Vingramine and Methylvingramine.

  1998cited by this paper
• Quantification of metabolites in the indole alkaloid pathways of catharanthus roseus: implications for metabolic engineering

  1998cited by this paper
• Influence of Precursor Availability on Alkaloid Accumulation by Transgenic Cell Line of Catharanthus roseus

  1998cited by this paper
• Analysis of several iridoid and indole precursors of terpenoid indole alkaloids with a single HPLC run.

  1996cited by this paper
• Involvement of strictosidine as a defensive chemical inCatharanthus roseus

  1996cited by this paper
• Terpenoid indole alkaloid biosynthesis and enzyme activities in two cell lines of Tabernaemontana divaricata

  1995cited by this paper
• Catharanthus roseus cell cultures: Growth, alkaloid synthesis and antidiabetic activity

  1994cited by this paper
• Quantitative analysis of serpentine and ajmalicine in plant tissues of Catharanthus roseus and hyoscyamine and scopolamine in root tissues of Datura stramonium by thin layer chromatography-densitometry

  1992cited by this paper
• Growth-related dimerization of vindoline and catharanthine in Catharanthus roseus and effect of wounding on the process

  1991cited by this paper
• Phagodeterrency Induced by Leaves and Leaf Extracts of Catharanthus roseus in the Larva of Spodoptera littoralis

  1981cited by this paper
• Alkaloid production in Catharanthus roseus cell cultures: Isolation and characterization of alkaloids from one cell line

  1980cited by this paper
• Adaptive Patterns in Alkaloid Physiology

  1974cited by this paper
• Effect of the Plant Alkaloid Sparteine on the Distribution of the Aphid Acyrthosiphon spartii (Koch.)

  1966cited by this paper
• A revised medium for rapid growth and bio assays with tobacco tissue cultures

  1962cited by this paper

• Recent advancements in the bioactive alkaloids analysis in plant and biological specimen: From the perspective of activity, sample preparation, and analytical method selection.

  2025cites this paper
• Use of LED light and plasma activated water (PAW) to stimulate pharmaceutical compound production in Catharanthus roseus plants

  2025cites this paper
• An insight into recent updates on analytical techniques for bioactive alkaloids.

  2024cites this paper
• Variations in metabolites content and bioactivity to regulate biomarkers of benign prostatic hyperplasia according to the growth stages of Sida rhombifolia

  2024cites this paper
• Characterization of the ZCTs, a subgroup of Cys2-His2 zinc finger transcription factors regulating alkaloid biosynthesis in Catharanthus roseus

  2024influential citation
• Next-Generation Sequencing in Medicinal Plants: Recent Progress, Opportunities, and Challenges

  2024cites this paper
• The leaf idioblastome of the medicinal plant Catharanthus roseus is associated with stress resistance and alkaloid metabolism

  2023cites this paper
• Idioblasts accumulating anticancer alkaloids in Catharanthus roseus leaves are a 3 unique cell type 4 5 Running title : The transcriptome of Catharanthus anticancer idioblasts 6 7

  2023cites this paper
• EASI Transformation Protocol: An Agrobacterium-Mediated Transient Transformation Protocol for Catharanthus roseus Seedlings.

  2022cites this paper
• Expression of CrMPK3 and alkaloid synthesis genes with antioxidants in callus of Catharanthus roseus in response to polyethylene glycol

  2022cites this paper
• Recent advances and future prospects of indole alkaloids producing endophytes from Catharanthus roseus

  2021cites this paper
• Higher Plant Sources of Cancer Chemotherapeutic Agents and the Potential Role of Biotechnological Approaches for Their Supply

  2021cites this paper
• The complexity of sound quantification of specialized metabolite biosynthesis: The stress related impact on the alkaloid content of Catharanthus roseus.

  2021cites this paper
• A plastid localized bona fide geranylgeranyl diphosphate synthase plays a necessary role in monoterpene indole alkaloid biosynthesis in Catharanthus roseus.

  2020cites this paper
• Liquid chromatographic separation of alkaloids in herbal medicines: Current status and perspectives.

  2020cites this paper
• Investigating distributions and changes of alkaloids in living Catharanthus roseus under low-phosphorus stress using wooden-tip electrospray ionisation mass spectrometry.

  2020cites this paper
• Interpol review of controlled substances 2016–2019☆

  2020cites this paper
• CrERF5, an AP2/ERF Transcription Factor, Positively Regulates the Biosynthesis of Bisindole Alkaloids and Their Precursors in Catharanthus roseus

  2019cites this paper
• Anticancer Molecules from Catharanthus roseus

  2019cites this paper
• High Pressure Liquid Chromatography Analysis of Alkaloids

  2019cites this paper
• Accumulation of terpenoid indole alkaloids in jasmonic acid elicited catharanthus roseus plants before and during flowering

  2018cites this paper
• Effectiveness of fine root fingerprinting as a tool to identify plants of the Alps: Results of a preliminary study

  2018cites this paper
• A UPLC-ESI-Q-TOF method for rapid and reliable identification and quantification of major indole alkaloids in Catharanthus roseus.

  2018cites this paper
• Development and validation of a new HPTLC method for quantification of conophylline in Tabernaemontana divaricata samples obtained from different seasons and extraction techniques: Insights into variation of pancreatic lipase inhibitory activity

  2018cites this paper
• Terpene Moiety Enhancement by Overexpression of Geranyl(geranyl) Diphosphate Synthase and Geraniol Synthase Elevates Monomeric and Dimeric Monoterpene Indole Alkaloids in Transgenic Catharanthus roseus

  2018cites this paper
• Identification, characterization and distribution of terpene indole alkaloids in ethanolic extracts of Catharanthus roseus using high-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry and the study of their geographical variation.

  2018cites this paper
• An engineered combinatorial module of transcription factors boosts production of monoterpenoid indole alkaloids in Catharanthus roseus.

  2018cites this paper
• Development of an HPLC-DAD method for the determination of five alkaloids in Stephania yunnanensis Lo and in rat plasma after oral dose of Stephania yunnanensis Lo extracts.

  2018cites this paper
• Short Communication: The impact of Gamma radiation on Tdc and Str gene expressions in Catharanthus roseus regenerated plantlets

  2018influential citation
• Application of Mobile Phases Containing Ionic Liquid for HPLC Analysis of Selected Isoquinoline Alkaloids.

  2017cites this paper
• Bis-indole alkaloids from Tabernaemontana divaricata as potent pancreatic lipase inhibitors: molecular modelling studies and experimental validation

  2017cites this paper
• Antineoplastic drugs and their analysis: a state of the art review.

  2017cites this paper
• Medicinal plant transcriptomes: the new gateways for accelerated understanding of plant secondary metabolism

  2016cites this paper