Ski, a modulator of wound healing and scar formation in the rat skin and rabbit ear

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Journal of Pathology

• Publication date

  2011-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/path.2831PMID 21341267
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Wound Repair and Regeneration

  2012cited by this paper
• c‐Ski promotes skin fibroblast proliferation but decreases type I collagen: implications for wound healing and scar formation

  2010cited by this paper
• Transforming growth factor β as a therapeutic target in systemic sclerosis

  2009cited by this paper
• Ski and SnoN, potent negative regulators of TGF-β signaling

  2009cited by this paper
• Homeostasis of the epidermal barrier layer: A theory of how occlusion reduces hypertrophic scarring

  2009cited by this paper
• Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled, phase I/II studies.

  2009cited by this paper
• Potential cellular and molecular causes of hypertrophic scar formation.

  2009cited by this paper
• Stimulated neovascularization, inflammation resolution and collagen maturation in healing rat cutaneous wounds by a heparan sulfate glycosaminoglycan mimetic, OTR4120

  2009cited by this paper
• Novel therapies for scar reduction and regenerative healing of skin wounds.

  2008cited by this paper
• GSK-3beta in mouse fibroblast controls wound healing and fibrosis through an endothelin-1-dependent mechanism.

  2008cited by this paper
• Effects of asiaticoside on the expression of Smad protein by normal skin fibroblasts and hypertrophic scar fibroblasts

  2008cited by this paper
• Expression and localization of Ski determine cell type–specific TGFβ signaling effects on the cell cycle

  2008cited by this paper
• Regulation of scar formation by vascular endothelial growth factor

  2008cited by this paper
• Biofilms and chronic wound inflammation.

  2008cited by this paper
• Melatonin accelerates the process of wound repair in full‐thickness incisional wounds

  2008cited by this paper
• Autocrine TGF-beta signaling in the pathogenesis of systemic sclerosis.

  2008cited by this paper
• GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism.

  2008cited by this paper
• Keloid and hypertrophic scars: a review of recent developments in pathogenesis and management.

  2008cited by this paper
• The essential role for c-Ski in mediating TGF-beta1-induced bi-directional effects on skin fibroblast proliferation through a feedback loop.

  2008cited by this paper
• Basic fibroblast growth factor (bFGF) alleviates the scar of the rabbit ear model in wound healing

  2008cited by this paper
• Ehlers-Danlos syndromes and Marfan syndrome.

  2008cited by this paper
• Scar treatments: preclinical and clinical studies.

  2008cited by this paper
• Accelerated re-epithelialization in Dpr2-deficient mice is associated with enhanced response to TGFβ signaling

  2008cited by this paper
• Autocrine TGF- signaling in the pathogenesis of systemic sclerosis

  2008cited by this paper
• [Current methods of treatment and prevention of pathologic scars].

  2007cited by this paper
• Gene therapy in wound healing: present status and future directions

  2007cited by this paper
• The Rho-kinase inhibitor H-1152P suppresses the wound-healing activities of human Tenon's capsule fibroblasts in vitro.

  2007cited by this paper
• Cutaneous Wound Healing

  2007cited by this paper
• Transient non‐viral cutaneous gene delivery in burn wounds

  2007cited by this paper
• TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease.

  2007cited by this paper
• A kóros hegek kezelésének és megelőzésének lehetőségei napjainkbanr

  2007cited by this paper
• TGF-β-induced EMT: mechanisms and implications for fibrotic lung disease

  2007cited by this paper
• Treatment of Keloids and Hypertrophic Scars

  2006cited by this paper
• Attenuation of mouse acute colitis by naked hepatocyte growth factor gene transfer into the liver

  2006cited by this paper
• Approach of transgenic disposition of wound healing models with the naked plasmid pcDNA 3.0 in vivo

  2006cited by this paper
• A role for the mitogen-activated protein kinase kinase kinase 1 in epithelial wound healing.

  2006cited by this paper
• Expression and possible mechanism of c‐ski, a novel tissue repair‐related gene during normal and radiation‐impaired wound healing

  2006cited by this paper
• Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.

  2006cited by this paper
• Novel Genomic Effects of Glucocorticoids in Epidermal Keratinocytes

  2006cited by this paper
• The temporal effects of anti-TGF-beta1, 2, and 3 monoclonal antibody on wound healing and hypertrophic scar formation.

  2005cited by this paper
• Mammalian fetal organ regeneration.

  2005cited by this paper
• Inflammatory cells during wound repair: the good, the bad and the ugly.

  2005cited by this paper
• Impaired wound healing after local soft x-ray irradiation in rat skin: time course study of pathology, proliferation, cell cycle, and apoptosis.

  2005cited by this paper
• Ski and SnoN: negative regulators of TGF-beta signaling.

  2004cited by this paper
• Scar-free healing: from embryonic mechanisms to adult therapeutic intervention.

  2004cited by this paper
• Ski and SnoN: negative regulators of TGF-β signaling

  2004cited by this paper
• c-Jun N-terminal kinase regulates lamellipodial protrusion and cell sheet migration during epithelial wound closure by a gene expression-independent mechanism.

  2004cited by this paper
• Inhibition of prolyl 4‐hydroxylase reduces scar hypertrophy in a rabbit model of cutaneous scarring

  2003cited by this paper
• Smad-dependent and Smad-independent pathways in TGF-β family signalling

  2003cited by this paper
• Fetal wound healing.

  2003cited by this paper
• Smad-dependent and Smad-independent pathways in TGF-beta family signalling.

  2003cited by this paper
• Non-viral liposomal keratinocyte growth factor (KGF) cDNA gene transfer improves dermal and epidermal regeneration through stimulation of epithelial and mesenchymal factors

  2002cited by this paper
• Loss of the SKI proto-oncogene in individuals affected with 1p36 deletion syndrome is predicted by strain-dependent defects in Ski−/− mice

  2002cited by this paper
• Up-regulated Transcriptional Repressors SnoN and Ski Bind Smad Proteins to Antagonize Transforming Growth Factor-β Signals during Liver Regeneration*

  2002cited by this paper
• Efficient gene expression in skin wound sites following local plasmid injection.

  2001cited by this paper
• Growth factor regulation and manipulation in wound repair: to scar or not to scar, that is the question

  2001cited by this paper
• Rho GTPases and cell migration-fibroblast wound healing.

  2000cited by this paper
• Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

  1999cited by this paper
• Cutaneous wound healing.

  1999cited by this paper
• Acute and Chronic Animal Models for Excessive Dermal Scarring: Quantitative Studies

  1997cited by this paper
• Role of Growth Factors in Scar Contraction: An In Vitro Analysis

  1996cited by this paper
• Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring.

  1995cited by this paper
• Neutralisation of TGF-β 1 and TGF-β 2 or exogenous addition of TGF-β 3 to cutaneous rat wounds reduces scarring

  1995cited by this paper
• Wound repair and regeneration

  1994cited by this paper
• A patient with Ehlers-Danlos syndrome type VI is a compound heterozygote for mutations in the lysyl hydroxylase gene.

  1994cited by this paper
• Neutralising antibody to TGF-beta 1,2 reduces cutaneous scarring in adult rodents.

  1994cited by this paper
• Fetal wound healing.

  1993cited by this paper
• Unique sequence, ski, in Sloan-Kettering avian retroviruses with properties of a new cell-derived oncogene

  1986cited by this paper
• Pathological Society of Great Britain and Ireland

  1984cited by this paper
• Online Supplemental Material

  year unknowncited by this paper

• An anti-FAP-scFv-functionalized exosome-carrying hydrogel delivers SKI mRNA to fibrotic nucleus pulposus cells to alleviate intervertebral disc degeneration by regulating FOXO3

  2025cites this paper
• c-Ski is a novel repressor of NF-κB through interaction with p65 and HDAC1 in U937 cells

  2025influential citation
• Hair-follicle-associated pluripotent (HAP) stem-cell-sheet implantation accelerates cutaneous wound closure and suppresses scar formation in a mouse model

  2025influential citation
• The Essential Role of Angiogenesis in Adenosine 2A Receptor Deficiency-mediated Impairment of Wound Healing Involving c-Ski via the ERK/CREB Pathways

  2024influential citation
• Ski ameliorates synovial cell inflammation in monosodium iodoacetate-induced knee osteoarthritis

  2024cites this paper
• Gallic Acid Treats Hypertrophic Scar in Rabbit Ears via the TGF-β/Smad and TRPC3 Signaling Pathways

  2023cites this paper
• EGCG inhibits hypertrophic scar formation in a rabbit ear model

  2023cites this paper
• Ski regulates proliferation and migration of reactive astrocytes induced by lipopolysaccharide (LPS) through PI3K/Akt pathway.

  2022cites this paper
• Ski regulates the inflammatory response of reactive astrocytes induced by oxygen glucose deprivation/reoxygenation (OGD/R) through the NF-κB pathway.

  2022cites this paper
• Overexpressed ski efficiently promotes neurorestoration, increases neuronal regeneration, and reduces astrogliosis after traumatic brain injury

  2022cites this paper
• Activation of NF-κB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion

  2021cites this paper
• A Review of Hypertrophic Scar and Keloid Treatment and Prevention in the Pediatric Population: Where Are We Now?

  2021cites this paper
• The Ubiquitin Proteasome System and Skin Fibrosis

  2021cites this paper
• Pharmaceutical Prophylaxis of Scarring with Emphasis on Burns: A Review of Preclinical and Clinical Studies

  2021cites this paper
• Ski: Double roles in cancers.

  2020cites this paper
• Ski mediates TGF-β1-induced fibrosarcoma cell proliferation and promotes tumor growth

  2020cites this paper
• Design, fabrication, and optimization of a dual function three-layer scaffold for controlled release of metformin hydrochloride to alleviate fibrosis and accelerate wound healing.

  2020cites this paper
• Ski Is Required for Tri-Methylation of H3K9 in Major Satellite and for Repression of Pericentromeric Genes: Mmp3, Mmp10 and Mmp13, in Mouse Fibroblasts.

  2020cites this paper
• Ski promotes proliferation and inhibits apoptosis in fibroblasts under high‐glucose conditions via the FoxO1 pathway

  2020cites this paper
• Development of a reproducible in vivo laser-induced scar model for wound healing study and management.

  2019cites this paper
• Bionic Poly(γ‐Glutamic Acid) Electrospun Fibrous Scaffolds for Preventing Hypertrophic Scars

  2019cites this paper
• SnoN residue (1–366) attenuates hypertrophic scars through resistance to transforming growth factor-β1-induced degradation

  2019cites this paper
• The ERK/CREB pathway is involved in the c-Ski expression induced by low TGF-β1 concentrations during primary fibroblast proliferation

  2018cites this paper
• Advancements in Regenerative Strategies Through the Continuum of Burn Care

  2018cites this paper
• Usnic acid inhibits hypertrophic scarring in a rabbit ear model by suppressing scar tissue angiogenesis.

  2018cites this paper
• Arsenic trioxide inhibits the differentiation of fibroblasts to myofibroblasts through nuclear factor erythroid 2‐like 2 (NFE2L2) protein and the Smad2/3 pathway

  2018cites this paper
• α-SMA Expression Increased Over Cell Passages and Decreased by Exogenous TGF-β1, In Vitro Studies on Myofibroblast Derived from Orbital Socket Contracture

  2018cites this paper
• Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches.

  2018cites this paper
• Transcriptional cofactors Ski and SnoN are major regulators of the TGF-β/Smad signaling pathway in health and disease

  2018cites this paper
• Effect of transforming growth factor-β 1 on the expression of peroxisome proliferator-activated receptor β and scar formation in rabbit ears

  2018cites this paper
• Spatiotemporal expression of Ski after rat spinal cord injury

  2017cites this paper
• Genome-wide DNA methylation profiling of the regenerative MRL/MpJ mouse and two normal strains.

  2017cites this paper
• Non-Coding RNAs: New Players in Skin Wound Healing

  2017cites this paper
• Biomaterials and tissue engineering for scar management in wound care

  2017cites this paper
• Insights into the key roles of epigenetics in matrix macromolecules-associated wound healing.

  2017cites this paper
• Expression of Ski and its role in astrocyte proliferation and migration.

  2017cites this paper
• Transforming growth factor beta (TGF‐β) isoforms in wound healing and fibrosis

  2016cites this paper
• Currently known risk factors for hypertrophic skin scarring: A review.

  2016cites this paper
• Comparative evaluation of the wound-healing potency of recombinant bFGF and ski gene therapy in rats

  2016cites this paper
• Transcriptional regulation of ski and scleraxis in primary cardiac myofibroblasts

  2016cites this paper
• Instructive Matrix Cues for Tissue Engineering Applications

  2016cites this paper
• Nanomaterials as a game changer in the management and treatment of diabetic foot ulcers

  2016cites this paper
• Biochemical and Biophysical Cues in Matrix Design for Chronic and Diabetic Wound Treatment

  2016cites this paper
• PLGA based drug delivery systems: Promising carriers for wound healing activity

  2016cites this paper
• MiR-1908 promotes scar formation post-burn wound healing by suppressing Ski-mediated inflammation and fibroblast proliferation

  2016cites this paper
• Ski diminishes TGF-β1-induced myofibroblast phenotype via up-regulating Meox2 expression.

  2014cites this paper
• New molecular medicine-based scar management strategies.

  2014influential citation
• Mesenchymal stem cells prevent hypertrophic scar formation via inflammatory regulation when undergoing apoptosis.

  2014cites this paper
• The Four-Herb Chinese Medicine ANBP Enhances Wound Healing and Inhibits Scar Formation via Bidirectional Regulation of Transformation Growth Factor Pathway

  2014cites this paper
• c‐Ski activates cancer‐associated fibroblasts to regulate breast cancer cell invasion

  2013cites this paper
• Inhibition of CCR7/CCL19 axis in lesional skin is a critical event for clinical remission induced by TNF blockade in patients with psoriasis.

  2013cites this paper
• Effect of Semisolid Formulation of Persea Americana Mill (Avocado) Oil on Wound Healing in Rats

  2013influential citation
• Dual growth factor releasing multi-functional nanofibers for wound healing.

  2013cites this paper
• Upregulation of Ski in Fibroblast is Implicated in the Peroxisome Proliferator- Activated Receptor δ-Mediated Wound Healing

  2012cites this paper
• Topical insulin application improves healing by regulating the wound inflammatory response

  2012cites this paper
• Inflammation: A Hallmark of Obesity in Conflict with Wound Healing

  2012cites this paper
• c-Ski in health and disease

  2011cites this paper