Cancer Protrusions on a Tightrope: Nanofiber Curvature Contrast Quantitates Single Protrusion Dynamics.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  ACS Nano

• Publication date

  2017-12-01

• Fields of study

  Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.1021/acsnano.7b04567PMID 29144730
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nanonet force microscopy for measuring forces in single smooth muscle cells of the human aorta

  2017cited by this paper
• Nanonet Force Microscopy for Measuring Cell Forces.

  2016cited by this paper
• Collective cancer cell invasion induced by coordinated contractile stresses

  2015cited by this paper
• Fibroblasts probe substrate rigidity with filopodia extensions before occupying an area

  2014cited by this paper
• Expression and prognostic significance of fibronectin and matrix metalloproteases in breast cancer metastasis

  2014cited by this paper
• Engineering strategies to mimic the glioblastoma microenvironment.

  2014cited by this paper
• 3D collagen alignment limits protrusions to enhance breast cancer cell persistence.

  2014cited by this paper
• Suspended micro/nanofiber hierarchical biological scaffolds fabricated using non-electrospinning STEP technique.

  2014cited by this paper
• Role of suspended fiber structural stiffness and curvature on single-cell migration, nucleus shape, and focal-adhesion-cluster length.

  2014cited by this paper
• Mammary epithelial cell interactions with fibronectin stimulate epithelial-mesenchymal transition

  2013cited by this paper
• Membrane tension in rapidly moving cells is determined by cytoskeletal forces.

  2013cited by this paper
• Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

  2013cited by this paper
• The Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3‐dimensional cancer cell migration

  2013cited by this paper
• The role of filopodia in the recognition of nanotopographies

  2013cited by this paper
• Microenvironment and tumor cell plasticity: an easy way out.

  2013cited by this paper
• Polymeric nanofibers: isodiametric design space and methodology for depositing aligned nanofiber arrays in single and multiple layers

  2013cited by this paper
• Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism

  2012cited by this paper
• Epithelial-Mesenchymal Transition Stimulates Human Cancer Cells to Extend Microtubule-based Invasive Protrusions and Suppresses Cell Growth in Collagen Gel

  2012cited by this paper
• Intravital third harmonic generation microscopy of collective melanoma cell invasion

  2012cited by this paper
• Breast cancer cell-derived matrix supports vascular morphogenesis.

  2012cited by this paper
• Interstitial guidance of cancer invasion

  2012cited by this paper
• Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients

  2012cited by this paper
• Trespassing cancer cells: 'fingerprinting' invasive protrusions reveals metastatic culprits.

  2012cited by this paper
• Extracellular matrix determinants of proteolytic and non-proteolytic cell migration.

  2011cited by this paper
• Targeting tumor cell motility to prevent metastasis.

  2011cited by this paper
• Aligned collagen is a prognostic signature for survival in human breast carcinoma.

  2011cited by this paper
• The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

  2011cited by this paper
• The role of the tissue microenvironment in the regulation of cancer cell motility and invasion

  2010cited by this paper
• Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia

  2010cited by this paper
• Dry Spinning Based Spinneret Based Tunable Engineered Parameters (STEP) Technique for Controlled and Aligned Deposition of Polymeric Nanofibers.

  2009cited by this paper
• Filopodia: Complex models for simple rods.

  2009cited by this paper
• Shedding microvesicles: artefacts no more.

  2009cited by this paper
• Mapping proteolytic cancer cell-extracellular matrix interfaces

  2009cited by this paper
• Regulation of actin assembly associated with protrusion and adhesion in cell migration.

  2008cited by this paper
• Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells.

  2008cited by this paper
• Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo

  2005cited by this paper
• Release of cell fragments by invading melanoma cells.

  2004cited by this paper
• Compensation mechanism in tumor cell migration

  2003cited by this paper
• Tumour-cell invasion and migration: diversity and escape mechanisms

  2003cited by this paper
• Intravital imaging of cell movement in tumours

  2003cited by this paper
• The Journal of Cell Biology

  2002cited by this paper
• Lamellipodia in invasion.

  2001cited by this paper
• Role of fibronectin-stimulated tumor cell migration in glioma invasion in vivo: clinical significance of fibronectin and fibronectin receptor expressed in human glioma tissues

  1998cited by this paper

• Topology Outweighs Stiffness: Self-Reinforced Cell Mechanotransduction via Multiaxial Curvature Engineering of Ultrasoft Hydrogels.

  2026cites this paper
• Quantifying cell traction forces at the single-fiber scale in 3D: An approach based on deformable photopolymerized fiber arrays

  2025cites this paper
• Mechanical cues guide the formation and patterning of 3D spheroids in fibrous environments

  2025cites this paper
• How multiscale curvature couples forces to cellular functions

  2024cites this paper
• Mesoscopic dynamic Monte Carlo simulations of fluctuating fluid membrane shaping in biological processes: a review

  2024cites this paper
• The Mechanobiology of Cells, Fibers, and Their Interactions

  2023cites this paper
• Long Prehensile Protrusions Can Facilitate Cancer Cell Invasion through the Basement Membrane

  2023cites this paper
• Experimental and theoretical model for the origin of coiling of cellular protrusions around fibers

  2023cites this paper
• A minimal cell model for lamellipodia-based cellular dynamics and migration.

  2023cites this paper
• Actin Filaments Couple the Protrusive Tips to the Nucleus through the I‐BAR Domain Protein IRSp53 during the Migration of Cells on 1D Fibers

  2023cites this paper
• Quantitative biophysical metrics for rapid evaluation of ovarian cancer metastatic potential

  2022influential citation
• Tunneling Nanotubes between Cells Migrating in ECM Mimicking Fibrous Environments

  2022cites this paper
• Quantifying protrusions as tumor-specific biophysical predictors of cancer invasion in in vitro tumor micro-spheroid models

  2022cites this paper
• Coiling of cellular protrusions around extracellular fibers

  2022cites this paper
• Combination of the Natural Product Mensacarcin with Vemurafenib (Zelboraf) Combats BRAF Mutant and Chemo-Resistant Melanoma in Vitro by Affecting Cell Metabolism and Cellular Migration

  2022cites this paper
• Fiber Diameter and Architecture Direct Three-Dimensional Assembly of Pericytes into Spheroids

  2022cites this paper
• Embracing Mechanobiology in Next Generation Organ-On-A-Chip Models of Bone Metastasis

  2021cites this paper
• Sculpting Rupture‐Free Nuclear Shapes in Fibrous Environments

  2021cites this paper
• Microfluidics-based Single-Cell Protrusion Analysis for Rapid Screening Drugs Targeting Subcellular Mitochondrial Trafficking in Cancer Progression.

  2020cites this paper
• Rules of contact inhibition of locomotion for cells on suspended nanofibers

  2020cites this paper
• Force-exerting perpendicular lateral protrusions in fibroblastic cell contraction

  2020cites this paper
• Tissue engineered platforms for studying primary and metastatic neoplasm behavior in bone.

  2020cites this paper
• Inositol polyphosphate multikinase is a metformin target that regulates cell migration

  2019cites this paper
• Integrating nanofibers with biochemical gradients to investigate physiologically-relevant fibroblast chemotaxis.

  2019cites this paper
• Cancer Cells Sense Fibers by Coiling on them in a Curvature-Dependent Manner

  2019cites this paper
• ECM in Differentiation: A Review of Matrix Structure, Composition and Mechanical Properties

  2019cites this paper
• Nano-twines to twine-bridges: Role of force exerting perpendicular lateral protrusions in fibroblastic cell contraction

  2019cites this paper
• Development of an in vitro 3D choroidal neovascularization model using chemically induced hypoxia through an ultra-thin, free-standing nanofiber membrane.

  2019cites this paper
• Crosshatch nanofiber networks of tunable interfiber spacing induce plasticity in cell migration and cytoskeletal response

  2019cites this paper
• Bioenergetics underlying single cell migration on aligned nanofiber scaffolds.

  2019cites this paper
• Design of Fiber Networks for Studying Metastatic Invasion.

  2018cites this paper