Knockdown of fascin1 expression suppresses the proliferation and metastasis of gastric cancer cells

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Pathology (Sydney)

• Publication date

  2009-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3109/00313020903273100PMID 20001345
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Epidemiology of stomach cancer.

  2009cited by this paper
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  2008cited by this paper
• Fascin overexpression in intraductal papillary mucinous neoplasms (adenomas, borderline neoplasms, and carcinomas) of the pancreas, correlated with increased histological grade

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• Fascin over-expression is associated with aggressiveness of oral squamous cell carcinoma.

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• Association of Cortactin and Fascin-1 Expression in Gastric Adenocarcinoma: Correlation With Clinicopathological Parameters

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• Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis.

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• Fascin is a potential biomarker for early-stage oesophageal squamous cell carcinoma

  2006cited by this paper
• Role of fascin in the proliferation and invasiveness of esophageal carcinoma cells.

  2005cited by this paper
• Fascin-1 expression in papillary and invasive urothelial carcinomas of the urinary bladder.

  2005cited by this paper
• The Prognostic Relevance of Fascin Expression in Human Gastric Carcinoma

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• Increased expression of fascin, motility associated protein, in cell cultures derived from ovarian cancer and in borderline and carcinomatous ovarian tumors

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• Multicomponent Analysis of the Pancreatic Adenocarcinoma Progression Model Using a Pancreatic Intraepithelial Neoplasia Tissue Microarray

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• Independent value of fascin immunoreactivity for predicting lymph node metastases in typical and atypical pulmonary carcinoids.

  2003cited by this paper
• Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin

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• Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer

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• Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro.

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• Actin‐binding protein fascin expression in skin neoplasia

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• Cell-matrix contact structures

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• Fascin, an actin-bundling protein associated with cell motility, is upregulated in hormone receptor negative breastancer

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• Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer.

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• C-erbB-2/ HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines

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• Why Are Two Different Cross-linkers Necessary for Actin Bundle Formation In Vivo and What Does Each Cross-link Contribute?

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• Serological identification of human tumor antigens.

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• Actin-bundling proteins.

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• Epidemiology of Stomach Cancer

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• Disabled homolog 2 is required for migration and invasion of prostate cancer cells

  2015cites this paper
• MicroRNA-145 inhibits migration and invasion via inhibition of fascin 1 protein expression in non-small-cell lung cancer cells.

  2015cites this paper
• TGF-β induces fascin expression in gastric cancer via phosphorylation of smad3 linker area.

  2015cites this paper
• MicroRNA-133a inhibits proliferation and invasion, and induces apoptosis in gastric carcinoma cells via targeting fascin actin-bundling protein 1.

  2015cites this paper
• Reverse Correlation between MicroRNA-145 and FSCN1 Affecting Gastric Cancer Migration and Invasion

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• Targeting epithelial-mesenchymal transition phenotype for gastro-intestinal cancer.

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• Down-regulation of miR-326 is associated with poor prognosis and promotes growth and metastasis by targeting FSCN1 in gastric cancer

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• The role of microRNA-133b and its target gene FSCN1 in gastric cancer

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• Signal transducer and activator of transcription 3 signaling upregulates fascin via nuclear factor-κB in gastric cancer: Implications in cell invasion and migration

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• The role of microRNA-133b and its target gene FSCN1 in gastric cancer

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• Fascin expression is related to poor survival in gastric cancer

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• A cell-based fascin bioassay identifies compounds with potential anti-metastasis or cognition-enhancing functions

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