Fluorescent probe for early mitochondrial voltage dynamics.

Mitochondrial voltage dynamics plays a crucial role in cell healthy and disease. Here, a new fluorescent probe to monitor mitochondrial early voltage variations is described. The slowly permeant probe is retained in mitochondria during measurements to avoid interferences from natural membrane potential by incorporating an hydrolizable ester function. Voltage, local polarity, pH parameters and transmembrane dynamics were found to be deeply correlated opening a approach in mitochondrial sensing.

• Publication year

  2021

• Venue

  Chemical Communications

• Publication date

  2021-05-06

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1039/d1cc01944aPMID 33956917
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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