Validation of chromogenic in situ hybridization for detection of EGFR copy number amplification in nonsmall cell lung carcinoma

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Modern Pathology

• Publication date

  2007-08-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/modpathol.3800946PMID 17673923
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Non-small cell lung cancer.

  2012cited by this paper
• Comparative analysis of epidermal growth factor receptor mutations and gene amplification as predictors of gefitinib efficacy in Japanese patients with nonsmall cell lung cancer

  2007cited by this paper
• Comparative analysis of epidermal growth factor receptor mutations and gene amplification as predictors of gefitinib efficacy in Japanese patients with nonsmall cell lung cancer

  2007cited by this paper
• Epidermal growth factor receptor mutations in lung cancer

  2007cited by this paper
• Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer.

  2006cited by this paper
• Memorial Sloan-Kettering Cancer

  2006cited by this paper
• Survival outcome and predictors of gefitinib antitumor activity in East Asian chemonaive patients with advanced nonsmall cell lung cancer

  2006cited by this paper
• Use of Chromogenic In Situ Hybridization to Identify MYCN Gene Copy Number in Neuroblastoma Using Routine Tissue Sections

  2006cited by this paper
• Chromogenic in-situ hybridization: a viable alternative to fluorescence in-situ hybridization in the HER2 testing algorithm

  2006cited by this paper
• Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.

  2006cited by this paper
• EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment.

  2005cited by this paper
• Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group Study.

  2005cited by this paper
• Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer.

  2005cited by this paper
• Gene amplification and protein expression of EGFR and HER2 by chromogenic in situ hybridisation and immunohistochemistry in atypical adenomatous hyperplasia and adenocarcinoma of the lung

  2005cited by this paper
• Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer.

  2005cited by this paper
• Reliability of chromogenic in situ hybridization for detecting HER-2 gene status in breast cancer: comparison with fluorescence in situ hybridization and assessment of interobserver reproducibility

  2005cited by this paper
• The 2004 World Health Organization classification of lung tumors.

  2005cited by this paper
• Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.

  2004cited by this paper
• EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

  2004cited by this paper
• Anticancer drugs: To the rescue?

  2004cited by this paper
• Pathology and genetics of tumours of the lung , pleura, thymus and heart

  2004cited by this paper
• Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis.

  2003cited by this paper
• AJCC Cancer Staging Manual

  2002cited by this paper
• AJCC Cancer Staging Manual. 6th ed

  2002cited by this paper
• Cigarette smoking is strongly associated with mutation of the K‐ras gene in patients with primary adenocarcinoma of the lung

  2001cited by this paper
• Chromogenic in situ hybridization: a practical alternative for fluorescence in situ hybridization to detect HER-2/neu oncogene amplification in archival breast cancer samples.

  2000cited by this paper
• Lipid-rich follicular carcinoma of the thyroid in a patient with McCune-Albright syndrome.

  1999cited by this paper
• Chromosome abnormalities in human non-small cell lung cancer.

  1992cited by this paper

• Impact of Chromosome 9 Numerical Imbalances in Oral Squamous Cell Carcinoma: A Pilot Grid-Based Centromere Analysis

  2020cites this paper
• Anti-tumor efficacy of theliatinib in esophageal cancer patient-derived xenografts models with epidermal growth factor receptor (EGFR) overexpression and gene amplification.

  2017cites this paper
• Anti-tumor efficacy of theliatinib in esophageal cancer patient-derived xenografts models with epidermal growth factor receptor (EGFR) overexpression and gene amplification

  2017cites this paper
• Chromosome 7 Multiplication in EGFR-positive Lung Carcinomas Based on Tissue Microarray Analysis.

  2017cites this paper
• The role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild-type colorectal cancer patients receiving irinotecan/cetuximab

  2017cites this paper
• Chromosomes 7/17 multiplication vs true polysomy: a crucial issue in lung and breast EGFR/HER2 dependent carcinoma cases.

  2016cites this paper
• Role of radiotherapy in adult ganglioneuroblastoma and ganglioneuroma

  2016influential citation
• Molecular assays in detecting EGFR gene aberrations: an updated HER2-dependent algorithm for interpreting gene signals; a short technical report.

  2016cites this paper
• Utilization of Chromogenic In Situ Hybridization to Assess Ploidy in the Diagnosis of Hydatidiform Mole.

  2016cites this paper
• Epidermal growth factor receptor and notch signaling in non‐small‐cell lung cancer

  2016cites this paper
• Myc protein expression correlates with MYC amplification in small‐cell lung carcinoma

  2015cites this paper
• EGFR mutation testing in pulmonary adenocarcinoma: evaluation of tumor cell number and tumor percent in paraffin sections of 120 small biopsies.

  2015cites this paper
• EGFR gene copy number alterations are not a useful screening tool for predicting EGFR mutation status in lung adenocarcinoma

  2014cites this paper
• Intratumoral distribution of EGFR-amplified and EGFR-mutated cells in pulmonary adenocarcinoma.

  2014cites this paper
• Molecular Pathology of Lung Cancers

  2013cites this paper
• Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung

  2013cites this paper
• Silver-enhanced In Situ Hybridization for Determination of EGFR Copy Number Alterations in Non–Small Cell Lung Cancer

  2012cites this paper
• Analysis of HER-3, insulin growth factor-1, nuclear factor-kB and epidermal growth factor receptor gene copy number in the prediction of clinical outcome for K-RAS wild-type colorectal cancer patients receiving irinotecan-cetuximab.

  2012cites this paper
• AKC İĞ ER KANSER İNDE İNTERFAZ FISH ANAL İZİ İLE KROMOZOMAL ANÖPLO İDİLER İN SAPTANMASI

  2012cites this paper
• EGFR in Early Non-small Cell Lung Cancer: Tyrosine Kinase Inhibition in a Neoadjuvant Trial

  2012cites this paper
• Evaluation of current methods to detect the mutations of epidermal growth factor receptor in non-small cell lung cancer patients

  2012cites this paper
• Improved method of detecting the ERG gene rearrangement in prostate cancer using combined dual-color chromogenic and silver in situ hybridization.

  2012cites this paper
• Molecular pathology of lung cancer: key to personalized medicine

  2012cites this paper
• Relapsing high grade mucoepidermoid carcinoma

  2012cites this paper
• Molecular Diagnosis of Lung Cancer

  2012cites this paper
• In-situ hybridization as a molecular tool in cancer diagnosis and treatment.

  2012cites this paper
• Comprehensive Analysis of Epidermal Growth Factor Receptor Gene Status in Lung Adenocarcinoma

  2011cites this paper
• The dichotomy in carcinogenesis of the distal esophagus and esophagogastric junction: intestinal-type vs cardiac-type mucosa-associated adenocarcinoma

  2011cites this paper
• The landscape of EGFR pathways and personalized management of non-small-cell lung cancer.

  2011cites this paper
• Molecular diagnostics of lung carcinomas.

  2011cites this paper
• Emerging concepts in the pathology and molecular biology of advanced non-small cell lung cancer.

  2011cites this paper
• EGFR and KRAS quality assurance schemes in pathology: generating normative data for molecular predictive marker analysis in targeted therapy

  2011cites this paper
• Chapter 12 – Immunohistology of Lung and Pleural Neoplasms

  2011cites this paper
• EGFR Mutation Is a Better Predictor of Response to Tyrosine Kinase Inhibitors in Non–Small Cell Lung Carcinoma Than FISH, CISH, and Immunohistochemistry

  2011cites this paper
• Clinicopathological predictors of EGFR/KRAS mutational status in primary lung adenocarcinomas

  2010cites this paper
• EGFR mutations and the terminal respiratory unit

  2010cites this paper
• Tissue and serum EGFR as prognostic factors in malignant pleural mesothelioma.

  2010cites this paper
• Detection of SYT and EWS gene rearrangements by dual-color break-apart CISH in liquid-based cytology samples of synovial sarcoma and Ewing sarcoma/primitive neuroectodermal tumor.

  2010cites this paper
• EGFR mutation is a better predictor of response to tyrosine kinase inhibitors in non-small cell lung carcinoma than FISH, CISH, and immunohistochemistry.

  2010cites this paper
• Climate change and health: a challenge for epidemiology and public health

  2010cites this paper
• Chromogenic in situ hybridization to detect EGFR gene copy number in cell blocks from fine-needle aspirates of non small cell lung carcinomas and lung metastases from colo-rectal cancer

  2010cites this paper
• Deregulated expression of the polycomb-group protein SUZ12 target genes characterizes mantle cell lymphoma.

  2010cites this paper
• Epidermal growth factor receptor gene amplification in atypical adenomatous hyperplasia of the lung.

  2010influential citation
• Molecular Diagnosis in Lung Cancer

  2010cites this paper
• Molecular Diagnostics Testing for Lung Adenocarcinoma: State-of-the-Art in 2010

  2010cites this paper
• Implementação da técnica Silver In Situ Hibridization para avaliação do status do gene EGFR em doentes com CPNPC

  2010cites this paper
• The role of epigenetic regulation in B-cell lymphomas

  2010cites this paper
• Tumorigenesis and Neoplastic Progression Deregulated Expression of the Polycomb-Group Protein SUZ 12 Target Genes Characterizes Mantle Cell Lymphoma

  2010cites this paper
• Targeted Therapies in Lung Cancer.

  2010cites this paper
• Epidermal Growth Factor Receptor (EGFR) gene copy number (GCN) correlates with clinical activity of irinotecan-cetuximab in K-RAS wild-type colorectal cancer: a fluorescence in situ (FISH) and chromogenic in situ hybridization (CISH) analysis

  2009cites this paper
• Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-smokers.

  2009cites this paper
• Chromogenic in situ hybridization analysis of EGFR gene copies in colon adenocarcinoma based on intra-operative imprints and tissue microarrays.

  2009cites this paper
• Comparison of FISH, PCR, and Immunohistochemistry in Assessing EGFR Status in Lung Adenocarcinoma and Correlation With Clinicopathologic Features

  2009cites this paper
• Overview of molecular testing in non-small-cell lung cancer: mutational analysis, gene copy number, protein expression and other biomarkers of EGFR for the prediction of response to tyrosine kinase inhibitors

  2009cites this paper
• EGFR Assays in Lung Cancer

  2008cites this paper
• Lung Biopsy: Special Techniques

  2008cites this paper
• EGFR mutations in lung adenocarcinomas: clinical testing experience and relationship to EGFR gene copy number and immunohistochemical expression.

  2008cites this paper
• Utility of Chromogenic In Situ Hybridization (CISH) for Detection of EGFR Amplification in Glioblastoma: Comparison With Fluorescence In Situ Hybridization (FISH)

  2008cites this paper
• Identifying Cancer Genes—A Review

  2007cites this paper
• Pilot Study of Neoadjuvant Treatment with Erlotinib in Nonmetastatic Head and Neck Squamous Cell Carcinoma

  2007cites this paper
• Chapter 11 – Immunohistology of Lung and Pleural Neoplasms

  2006cites this paper