Why the Biomedical Research Paradigm Must Change if we are to Win the “War on Cancer”

S. Knox

Published 2020 in American Journal of Biomedical Science & Research

ABSTRACT

Objectives: The purpose of this article is to begin a dialogue concerning the consequences for research design and data interpretation of outdated assumptions underpinning current biomedical research. Methods: Integrated analysis and review of the ways in which the exclusion of physics (quantum theory) and biophysics data (endogenous bioelectric signaling) in biomedicine have biased research design and data interpretation. Concrete consequences for clinical oncology research are used as illustrations. Results: Accumulating data demonstrate that biomedicine is about 100 years out of date with respect to its understanding of physics. This has led to detrimental consequences for clinical oncology. Conclusions: Evidence based medicine is only as good as the completeness and veracity of the data that support it. Widespread emphasis on particulate aspects of wave/particle duality to the exclusion of wave characteristics in biomedical research designs have seriously biased the data we collect and the interpretation of their clinical implications. It is time to integrate biophysics into mainstream oncology research.

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