Crystal structure of putidaredoxin reductase from Pseudomonas putida, the final structural component of the cytochrome P450cam monooxygenase.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Molecular Biology

• Publication date

  2004-02-27

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/J.JMB.2003.12.067PMID 15095867
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Crystal structure of putidaredoxin, the [2Fe-2S] component of the P450cam monooxygenase system from Pseudomonas putida.

  2003cited by this paper
• Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor

  2002cited by this paper
• The harlequin mouse mutation downregulates apoptosis-inducing factor

  2002cited by this paper
• DNA binding is required for the apoptogenic action of apoptosis inducing factor

  2002cited by this paper
• The crystal structure of the mouse apoptosis-inducing factor AIF

  2002cited by this paper
• Putidaredoxin Reductase, a New Function for an Old Protein*

  2002cited by this paper
• Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death?

  2002cited by this paper
• Adrenodoxin Reductase-Adrenodoxin Complex Structure Suggests Electron Transfer Path in Steroid Biosynthesis*

  2001cited by this paper
• Laser flash induced electron transfer in P450cam monooxygenase: putidaredoxin reductase-putidaredoxin interaction.

  2001cited by this paper
• Benign Synthesis of 2-Ethylhexanoic Acid by Cytochrome P450cam: Enzymatic, Crystallographic, and Theoretical Studies†

  2001cited by this paper
• A virtual high throughput screen for high affinity cytochrome P450cam substrates. Implications for in silico prediction of drug metabolism

  2001cited by this paper
• A virtual high throughput screen for high affinity cytochrome P450cam substrates. Implications for in silico prediction of drug metabolism

  2001cited by this paper
• NADH Oxidase Activity of Mitochondrial Apoptosis-inducing Factor*

  2001cited by this paper
• Benign synthesis of 2-ethylhexanoic acid by cytochrome P450cam: enzymatic, crystallographic, and theoretical studies.

  2001cited by this paper
• Crystal structure of NADH-dependent ferredoxin reductase component in biphenyl dioxygenase.

  2000cited by this paper
• Aromatic hydrocarbon dioxygenases in environmental biotechnology.

  2000cited by this paper
• The tertiary structure of full-length bovine adrenodoxin suggests functional dimers.

  2000cited by this paper
• The structure of adrenodoxin reductase of mitochondrial P450 systems: electron transfer for steroid biosynthesis.

  1999cited by this paper
• Molecular characterization of mitochondrial apoptosis-inducing factor

  1999cited by this paper
• Isothermal titration calorimetric studies on the associations of putidaredoxin to NADH-putidaredoxin reductase and P450cam.

  1998cited by this paper
• Roles of negatively charged surface residues of putidaredoxin in interactions with redox partners in p450cam monooxygenase system.

  1998cited by this paper
• NMR studies of putidaredoxin: associations of putidaredoxin with NADH-putidaredoxin reductase and cytochrome p450cam.

  1998cited by this paper
• Multiple sequence alignment with Clustal X.

  1998cited by this paper
• THE DIOXYGENASE-CATALYSED FORMATION OF VICINAL CIS-DIOLS

  1998cited by this paper
• Role of active site tyrosine residues in catalysis by human glutathione reductase.

  1998cited by this paper
• Crystallography & NMR system: A new software suite for macromolecular structure determination.

  1998cited by this paper
• [20] Processing of X-ray diffraction data collected in oscillation mode.

  1997cited by this paper
• Molecular recognition and electron transfer in mitochondrial steroid hydroxylase systems.

  1997cited by this paper
• Probing the Interactions of Putidaredoxin with Redox Partners in Camphor P450 5-Monooxygenase by Mutagenesis of Surface Residues*

  1997cited by this paper
• Structure-function analysis of the bacterial aromatic ring-hydroxylating dioxygenases.

  1997cited by this paper
• Processing of X-ray diffraction data collected in oscillation mode.

  1997cited by this paper
• Cytochrome P450: structure, function, and generation of reactive oxygen species.

  1996cited by this paper
• A structure-based model for cytochrome P450cam-putidaredoxin interactions.

  1996cited by this paper
• Enzyme-catalyzed dehalogenation of pentachloroethane: why F87W-cytochrome P450cam is faster than wild type.

  1995cited by this paper
• An NMR-derived model for the solution structure of oxidized putidaredoxin, a 2-Fe, 2-S ferredoxin from Pseudomonas.

  1994cited by this paper
• Substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2 A resolution.

  1994cited by this paper
• The CCP4 suite: programs for protein crystallography.

  1994cited by this paper
• Substrate interactions between trypanothione reductase and N1-glutathionylspermidine disulphide at 0.28-nm resolution.

  1993cited by this paper
• Functional and evolutionary relationships among diverse oxygenases.

  1992cited by this paper
• The refined crystal structure of Pseudomonas putida lipoamide dehydrogenase complexed with NAD+ at 2.45 Å resolution

  1992cited by this paper
• Reconstitution of cytochrome P4502B4 (LM2) activity with camphor and linalool monooxygenase electron donors.

  1992cited by this paper
• Atomic structure of ferredoxin-NADP+ reductase: prototype for a structurally novel flavoenzyme family.

  1991cited by this paper
• Improved methods for building protein models in electron density maps and the location of errors in these models.

  1991cited by this paper
• Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

  1991cited by this paper
• Putidaredoxin reductase and putidaredoxin. Cloning, sequence determination, and heterologous expression of the proteins.

  1990cited by this paper
• Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

  1990cited by this paper
• Use of a site-directed triple mutant to trap intermediates: demonstration that the flavin C(4a)-thiol adduct and reduced flavin are kinetically competent intermediates in mercuric ion reductase.

  1990cited by this paper
• X-ray structure of lipoamide dehydrogenase from Azotobacter vinelandii determined by a combination of molecular and isomorphous replacement techniques.

  1989cited by this paper
• cDNA sequence of adrenodoxin reductase. Identification of NADP-binding sites in oxidoreductases.

  1989cited by this paper
• Switching kinetic mechanism and putative proton donor by directed mutagenesis of glutathione reductase.

  1989cited by this paper
• The reduction of putidaredoxin reductase by reduced pyridine nucleotides.

  1988cited by this paper
• The oxidation of reduced putidaredoxin reductase by oxidized putidaredoxin.

  1988cited by this paper
• High-resolution crystal structure of cytochrome P450cam.

  1987cited by this paper
• Nucleotide sequence of the Pseudomonas putida cytochrome P-450cam gene and its expression in Escherichia coli.

  1986cited by this paper
• The involvement of carboxylate groups of putidaredoxin in the reaction with putidaredoxin reductase.

  1986cited by this paper
• Prediction of the Occurrence of the ADP-binding βαβ-fold in Proteins, Using an Amino Acid Sequence Fingerprint

  1986cited by this paper
• Prediction of the occurrence of the ADP-binding beta alpha beta-fold in proteins, using an amino acid sequence fingerprint.

  1986cited by this paper
• Structural relationship between glutathione reductase and lipoamide dehydrogenase.

  1984cited by this paper
• Reconstitution of Escherichia coli thioredoxin reductase with 1-deazaFAD. Evidence for 1-deazaFAD C-4a adduct formation linked to the ionization of an active site base.

  1984cited by this paper
• Adrenodoxin interaction with adrenodoxin reductase and cytochrome P-450scc. Cross-linking of protein complexes and effects of adrenodoxin modification by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide.

  1984cited by this paper
• Purification and properties of putidaredoxin reductase.

  1983cited by this paper
• Purification and properties of putidaredoxin reductase.

  1983cited by this paper
• The catalytic mechanism of glutathione reductase as derived from x-ray diffraction analyses of reaction intermediates.

  1983cited by this paper
• Mechanisms of ionic activation of adrenal mitochondrial cytochromes P-450scc and P-45011 beta.

  1981cited by this paper
• Ionic effects on adrenal steroidogenic electron transport. The role of adrenodoxin as an electron shuttle.

  1979cited by this paper
• Reactions of pig heart lipoamide dehydrogenase with pyridine nucleotides. Evidence for an effector role for bound oxidized pyridine nucleotide.

  1979cited by this paper
• Adrenodoxin reductase.adrenodoxin complex. Flavin to iron-sulfur electron transfer as the rate-limiting step in the NADPH-cytochrome c reductase reaction.

  1979cited by this paper
• Bacterial P-450cam methylene monooxygenase components: cytochrome m, putidaredoxin, and putidaredoxin reductase.

  1978cited by this paper
• A soluble cytochrome P-450 functional in methylene hydroxylation.

  1968cited by this paper

• The Role of Dioxygen in Microbial Bio-Oxygenation: Challenging Biochemistry, Illustrated by a Short History of a Long Misunderstood Enzyme

  2024influential citation
• Preparation of reductases for multicomponent oxygenases.

  2024cites this paper
• The role of the active site lysine residue on FAD reduction by NADPH in glutathione reductase

  2024cites this paper
• Cymredoxin, a [2Fe-2S] ferredoxin, supports catalytic activity of the p-cymene oxidising P450 enzyme CYP108N12.

  2023cites this paper
• The Role of the si-Face Tyrosine of a Homodimeric Ferredoxin-NADP+ Oxidoreductase from Bacillus subtilis during Complex Formation and Redox Equivalent Transfer with NADP+/H and Ferredoxin

  2023cites this paper
• Biochemical and structural characterization of a robust and thermostable ascorbate recycling monodehydroascorbate reductase (MDHAR) from stress adapted pearl millet.

  2023cites this paper
• Overview of structurally homologous flavoprotein oxidoreductases containing the low Mr thioredoxin reductase-like fold - A functionally diverse group.

  2021cites this paper
• Molecular design of high-efficacy and high drug safety Fluoroquinolones suitable for a variety of aerobic biodegradation bacteria.

  2021cites this paper
• Expression, purification and crystal structure determination of a ferredoxin reductase from the actinobacterium Thermobifida fusca

  2020cites this paper
• Unexpected Differences Between Two Closely Related Bacterial P450 Camphor Monooxygenases.

  2020cites this paper
• Molecular mechanism of metabolic NAD(P)H-dependent electron-transfer systems: The role of redox cofactors.

  2019cites this paper
• Review of NAD(P)H-dependent oxidoreductases: Properties, engineering and application.

  2018cites this paper
• Characterization of Cytochrome P450 Enzymes and Their Applications in Synthetic Biology.

  2018cites this paper
• Electron transfer ferredoxins with unusual cluster binding motifs support secondary metabolism in many bacteria

  2018cites this paper
• Molecular and Functional Characterization of Monodehydro-ascorbate and Dehydroascorbate Reductases

  2017cites this paper
• Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics.

  2017cites this paper
• Human Cytochrome P450 (CYP1A2)‐dsDNA Interaction in situ Evaluation Using a dsDNA‐electrochemical Biosensor

  2017cites this paper
• Bioorganometallic chemistry: Co-factor regeneration, enzyme recognition of biomimetic 1,4-NADH analogs, and organic synthesis; tandem catalyzed regioselective formation of N-substituted-1,4-dihydronicotinamide derivatives with [Cp*Rh(bpy)H]+, coupled to chiral S-alcohol formation with HLADH, and eng

  2017cites this paper
• Oxidation of 3-Chloroindole and Biodegradation of Dialkoxybenzenes with Cytochrome P450cam (CYP101A1)

  2016cites this paper
• Kinetics of NADP+/NADPH reduction–oxidation catalyzed by the ferredoxin-NAD(P)+ reductase from the green sulfur bacterium Chlorobaculum tepidum

  2016cites this paper
• Structure and catalytic mechanism of monodehydroascorbate reductase, MDHAR, from Oryza sativa L. japonica

  2016cites this paper
• Molecular dynamics of the P450cam–Pdx complex reveals complex stability and novel interface contacts

  2015cites this paper
• Differential molecular response of monodehydroascorbate reductase and glutathione reductase by nitration and S-nitrosylation

  2015influential citation
• Structures of Cytochrome P450 Enzymes

  2015cites this paper
• Predicting Flavin and Nicotinamide Adenine Dinucleotide-Binding Sites in Proteins Using the Fragment Transformation Method

  2015cites this paper
• A Single Mutation at the Ferredoxin Binding Site of P450 Vdh Enables Efficient Biocatalytic Production of 25‐Hydroxyvitamin D3

  2013cites this paper
• Synergistic effects of mutations in cytochrome P450cam designed to mimic CYP101D1.

  2013cites this paper
• The oxido-reductase activity of the apoptosis inducing factor: a promising pharmacological tool?

  2013cites this paper
• Structural Basis for Effector Control and Redox Partner Recognition in Cytochrome P450

  2013cites this paper
• Insights into the structural basis for activity and selectivity of P450 BM3 monooxygenase

  2013cites this paper
• Semi‐rational engineering of cytochrome P450sca‐2 in a hybrid system for enhanced catalytic activity: Insights into the important role of electron transfer

  2013cites this paper
• Das Metagenom als Quelle neuer oxidativer Enzyme für die Biotechnologie

  2013influential citation
• Characterisation of the paramagnetic [2Fe-2S]+ centre in palustrisredoxin-B (PuxB) from Rhodopseudomonas palustris CGA009: g-matrix determination and spin coupling analysis.

  2012cites this paper
• Biochemical Processes and Metal Complexes’ Role as Catalysts

  2012cites this paper
• Suppression of Electron Transfer to Dioxygen by Charge Transfer and Electron Transfer Complexes in the FAD-dependent Reductase Component of Toluene Dioxygenase*

  2012cites this paper
• Electron transfer between the reductase and ferredoxin component of toluene dioxygenase

  2012cites this paper
• Analiza wpływu surowców roślinnych na poziom ekspresji wysoce konserwatywnych izoenzymów cytochromu P-450 CYP1A2 i CYP2E1 u szczurów

  2012cites this paper
• Automated high-throughput approaches for the development and investigation of novel oxidative biocatalytic processes

  2012cites this paper
• Structural biology of redox partner interactions in P450cam monooxygenase: a fresh look at an old system.

  2011cites this paper
• Atomic force microscopy visualization and measurement of the activity and physicochemical properties of single monomeric and oligomeric enzymes

  2011cites this paper
• Steroid transformation by Rhodococcus strains and bacterial cytochrome P450 enzymes

  2011cites this paper
• Nonplanar peptide bonds in proteins are common and conserved but not biased toward active sites

  2011cites this paper
• Mechanisms of electron transfer from cytochrome P450 reductase to cytochrome P450 3A4.

  2010cites this paper
• Production and characterization of a functional putidaredoxin reductase-putidaredoxin covalent complex.

  2010cites this paper
• Asymmetric dimeric structure of ferredoxin-NAD(P)+ oxidoreductase from the green sulfur bacterium Chlorobaculum tepidum: implications for binding ferredoxin and NADP+.

  2010cites this paper
• Evidence that the amino acid residue Cys117 of chloroplastic monodehydroascorbate reductase is involved in its activity and structural stability.

  2010cites this paper
• Molecular Characterization of a Class I P450 Electron Transfer System from Novosphingobium aromaticivorans DSM12444*

  2010cites this paper
• Crystal structure analysis of Bacillus subtilis ferredoxin‐NADP+ oxidoreductase and the structural basis for its substrate selectivity

  2010cites this paper
• Crystal Structure of the Putidaredoxin Reductase·Putidaredoxin Electron Transfer Complex*

  2010cites this paper
• Crystallization and preliminary X-ray diffraction studies of a ferredoxin reductase component of carbazole 1,9a-dioxygenase from Novosphingobium sp. KA1.

  2010influential citation
• Arginines 65 and 310 in putidaredoxin reductase are critical for interaction with putidaredoxin.

  2010cites this paper
• Comparative investigation of PdR by usual and ultrafine atomic force microscopy

  2010cites this paper
• Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris

  2009cites this paper
• Redox Control of Protein Conformation in Flavoproteins

  2009cites this paper
• Coenzyme binding and hydride transfer in Rhodobacter capsulatus ferredoxin/flavodoxin NADP(H) oxidoreductase.

  2009cites this paper
• Modellierung von Cytochrom P450-Monooxygenasen

  2008cites this paper
• Structural and functional diversity of ferredoxin-NADP(+) reductases.

  2008cites this paper
• Engineering Cytochrome P450 Enzymes for Improved Activity towards Biomimetic 1,4‐NADH Cofactors

  2008cites this paper
• UNTERSUCHUNGEN ZUR SELEKTIVEN ENZYMATISCHEN HYDROXYLIERUNG VON FETTSÄUREN

  2008cites this paper
• Protein engineering of P450BM3 by rational redesign

  2008cites this paper
• Redox-dependent Changes in Molecular Properties of Mitochondrial Apoptosis-inducing Factor*

  2008cites this paper
• Designing a whole-cell biotransformation system in Escherichia coli using cytochrome P450 from Streptomyces peucetius

  2008cites this paper
• Linking cytochrome P450cam (Cyp101) to its redox partner putidaredoxin and probing new reactions of the P450cam system

  2008cites this paper
• Cytochrome P450--redox partner fusion enzymes.

  2007cites this paper
• Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily.

  2007cites this paper
• Association and redox properties of the putidaredoxin reductase-nicotinamide adenine dinucleotide complex.

  2007cites this paper
• Cytochrome P450 systems--biological variations of electron transport chains.

  2007cites this paper
• Crystal structure of the electron transfer complex rubredoxin–rubredoxin reductase of Pseudomonas aeruginosa

  2007cites this paper
• Crystallization and preliminary X-ray diffraction studies of a ferredoxin reductase from Rhodopseudomonas palustris CGA009.

  2007cites this paper
• Molecular mechanism of the redox-dependent interaction between NADH-dependent ferredoxin reductase and Rieske-type [2Fe-2S] ferredoxin.

  2007cites this paper
• Putidaredoxin-to-cytochrome P450cam electron transfer: differences between the two reductive steps required for catalysis.

  2006cites this paper
• Aromatic Ring Hydroxylating Dioxygenases

  2006cites this paper
• Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni has a large tunnel for substrate and oxygen access to the active site.

  2006cites this paper
• Iron: Heme Proteins, Mono- & Dioxygenases

  2006cites this paper
• Biodiversity of cytochrome P450 redox systems.

  2005cites this paper
• MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51.

  2005cites this paper
• The Putidaredoxin Reductase-Putidaredoxin Electron Transfer Complex

  2005cites this paper
• Cytochrome P450s: creating novel ligand sets.

  2005cites this paper
• STRUCTURAL AND FUNCTIONAL DIVERSITY IN HEME MONOOXYGENASES

  2005cites this paper
• Purification and cDNA Cloning of Chloroplastic Monodehydroascorbate Reductase from Spinach

  2005cites this paper
• Molekulare Analyse der Gene und Proteine der Cytochrom P450-haltigen Morpholin-Monooxygenase aus Mycobacterium sp. Stamm HE5

  2005cites this paper
• Analysis of the nearly identical morpholine monooxygenase-encoding mor genes from different Mycobacterium strains and characterization of the specific NADH : ferredoxin oxidoreductase of this cytochrome P450 system.

  2005cites this paper
• Conformational diversity in NAD(H) and interacting transhydrogenase nicotinamide nucleotide binding domains.

  2005cites this paper
• Characterisacion of flavocytochrome P450 BM3 site directed mutants with novel heme ligation state

  2005cites this paper
• Transient complexes of redox proteins: structural and dynamic details from NMR studies

  2004cites this paper