EphA3 Null Mutants Do Not Demonstrate Motor Axon Guidance Defects

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Molecular and Cellular Biology

• Publication date

  2003-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.23.22.8092-8098.2003PMID 14585969PMCID PMC262425
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A role for the EphA family in the topographic targeting of vomeronasal axons.

  2001cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Genetic and epigenetic mechanisms contribute to motor neuron pathfinding

  2000cited by this paper
• Expression of EphA4, Ephrin-A2 and Ephrin-A5 during Axon Outgrowth to the Hindlimb Indicates Potential Roles in Pathfinding

  2000cited by this paper
• Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons.

  2000cited by this paper
• Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping.

  2000cited by this paper
• Topographic mapping from the retina to the midbrain is controlled by relative but not absolute levels of EphA receptor signaling.

  2000cited by this paper
• Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers.

  2000influential reference
• Expression of Eph receptor tyrosine kinases and their ligands in chick embryonic motor neurons and hindlimb muscles

  1999cited by this paper
• Eph receptors and ephrins in neural development.

  1999cited by this paper
• Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axons.

  1999cited by this paper
• LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons.

  1998cited by this paper
• EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract.

  1998cited by this paper
• Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system.

  1998cited by this paper
• The Eph family in retinal axon guidance.

  1997cited by this paper
• The inhibitory effect on neurite outgrowth of motoneurons exerted by the ligands ELF-1 and RAGS.

  1997cited by this paper
• Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors

  1997cited by this paper
• The Eph receptor family: axonal guidance by contact repulsion.

  1997cited by this paper
• Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.

  1996cited by this paper
• Regulation of topographic projection in the brain: Elf-1 in the hippocamposeptal system.

  1996cited by this paper
• The Eph kinase ligand AL-1 is expressed by rostral muscles and inhibits outgrowth from caudal neurons.

  1996cited by this paper
• Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo.

  1996cited by this paper
• Expression of the Tyro4/Mek4/Cek4 gene specifically marks a subset of embryonic motor neurons and their muscle targets.

  1996cited by this paper
• Distinct and overlapping expression patterns of ligands for Eph-related receptor tyrosine kinases during mouse embryogenesis.

  1996cited by this paper
• Eph family receptors and their ligands distribute in opposing gradients in the developing mouse retina.

  1996cited by this paper
• From tags to RAGS: chemoaffinity finally has receptors and ligands.

  1995cited by this paper
• In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases.

  1995cited by this paper
• From tags to RAGS: Chemoaffinity finally has receptors and ligands

  1995cited by this paper
• Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map.

  1995cited by this paper
• Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation.

  1995cited by this paper
• Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis.

  1995cited by this paper
• Telling axons where to grow: a role for Eph receptor tyrosine kinases in guidance.

  1995cited by this paper
• Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes.

  1994cited by this paper
• Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases.

  1994cited by this paper
• Development of the spinal nerves in the mouse with special reference to innervation of the axial musculature

  1994cited by this paper
• Motor innervation of dorsoventrally reversed wings in chick/quail chimeric embryos

  1993cited by this paper
• A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes

  1993cited by this paper
• The influence of presumptive limb connective tissue on motoneuron axon guidance.

  1991cited by this paper
• Cells and cell‐interactions that guide motor axons in the developing chick embryo

  1991cited by this paper
• Cells and cell-interactions that guide motor axons in the developing chick embryo.

  1991cited by this paper
• A review of the organization and evolution of motoneurons innervating the axial musculature of vertebrates.

  1987cited by this paper
• Topographic mapping of motor pools onto skeletal muscles

  1987cited by this paper
• Proximal tissues and patterned neurite outgrowth at the lumbosacral level of the chick embryo: deletion of the dermamyotome.

  1987cited by this paper
• Pathway selection by embryonic chick motoneurons in an experimentally altered environment

  1981cited by this paper
• Organization of motor pools in the chick lumbar lateral motor column

  1980cited by this paper
• Motoneurone projection patterns in the chick hind limb following early partial reversals of the spinal cord.

  1980cited by this paper
• The development of motor projection patterns in the chick hind limb.

  1978cited by this paper

• Essential function of Nr4a2 in subicular development and social novelty.

  2025cites this paper
• Developmental and transcriptional programs that define the initiation of the forelimb

  2025cites this paper
• Cell-Extrinsic Differentiation Block Mediated by EphA3 in Pre-Leukaemic Thymus Contributes to Disease Progression

  2021cites this paper
• Analysis of Whole Genome Sequencing in a Cohort of Individuals with PHACE Syndrome Suggests Dysregulation of RAS/PI3K Signaling

  2021cites this paper
• Cell-extrinsic effects in T cell acute lymphoblastic pre-leukemia stem cells mediated by EphA3

  2020cites this paper
• Development and Arealization of the Cerebral Cortex.

  2019cites this paper
• Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA

  2019cites this paper
• Neogenin function and modulation in spinal motor neuron development

  2018cites this paper
• Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer

  2017cites this paper
• Studying the functional relevance of lung cancer genetic drivers in their physiological niche

  2016influential citation
• Treatment of non-small cell lung cancer (NSCLC) is based on histological analysis and molecular profiling of targetable driver

  2015cites this paper
• Mouse Models of Receptor Tyrosine Kinases

  2015cites this paper
• Role of EPHA3 in colorectal cancer

  2015cites this paper
• The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis

  2015cites this paper
• Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate

  2014cites this paper
• A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3

  2013cites this paper
• Polysialylated NCAM and ephrinA/EphA regulate synaptic development of GABAergic interneurons in prefrontal cortex.

  2013cites this paper
• EPHA3 as a novel therapeutic target in the hematological malignancies

  2012cites this paper
• Anatomical coupling of sensory and motor nerve trajectory via axon tracking.

  2011cites this paper
• Learning and memory impairment in Eph receptor A6 knockout mice.

  2008cites this paper
• Segregation of Axial Motor and Sensory Pathways via Heterotypic Trans-Axonal Signaling

  2008cites this paper
• Eph receptors and ephrin ligands in axon guidance.

  2007cites this paper
• A critical role for the EphA3 receptor tyrosine kinase in heart development.

  2007influential citation
• Microarray analysis of PDGFRα[+] populations in ES cell differentiation culture identifies genes involved in differentiation of mesoderm and mesenchyme including ARID3b that is essential for development of embryonic mesenchymal cells

  2006cites this paper
• Upregulation of EphA3 Receptor after Spinal Cord Injury

  2005cites this paper
• Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia

  2005cites this paper
• Eph Receptor Tyrosine Kinases in Angiogenesis: From Development to Disease

  2004cites this paper