Impact of postoperative hypothermia on outcomes after off-pump coronary artery bypass grafting

Background Even though the physiological derangements caused by hypothermia are well described, there is no consensus about its impact on postoperative outcomes. The aim of this study is to assess the effect of postoperative hypothermia on outcomes after off-pump coronary artery bypass surgery. Methods A total of 1979 patients undergoing isolated off-pump coronary artery bypass surgery in a single center in the period 2007–2018 were classified according to their axillary temperature measurement at intensive care unit admission postoperatively to either hypothermic (<36°C) or normothermic (≥36°C). Between-group differences on baseline characteristics and postoperative outcomes were assessed before and after propensity score matching. Results Data analysis showed that 582 patients (29.4%) were hypothermic (median temperature 35.5°C) and 1397 patients (70.6%) were normothermic (median temperature 36.4°C). Using propensity score matching, 567 patient pairs were created. Patients with hypothermia exhibited a higher rate of postoperative transfusion of at least three red cell concentrate units (14.3% vs 9%, p = 0.005), a longer intubation duration (median duration, 6 vs 5 h, p < 0.0001), and a longer intensive care unit stay (median stay, 1.6 vs 1.3 days, p = 0.008). There was no difference in reoperation for bleeding, renal replacement therapy, infections, and mortality between the two groups. Conclusions Even though associated with a higher blood transfusion requirement and a slightly longer intensive care unit stay, mild postoperative hypothermia was not associated with a higher morbidity and mortality.

• Publication year

  2021

• Venue

  Asian Cardiovascular and Thoracic Annals

• Publication date

  2021-05-25

• Fields of study

  Medicine

• Identifiers
  DOI 10.1177/02184923211019530PMID 34034509
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The influence of body mass index on temperature management during general anaesthesia—A prospective observational study

  2018cited by this paper
• Thermoregulation and age.

  2018cited by this paper
• Modeling of Gender Differences in Thermoregulation.

  2017cited by this paper
• Impact of Postoperative Hypothermia on Outcomes in Coronary Artery Bypass Surgery Patients.

  2017influential reference
• The effect of body mass index on perioperative thermoregulation

  2016cited by this paper
• Postoperative hypothermia and patient outcomes after major elective non‐cardiac surgery

  2013cited by this paper
• Postoperative hypothermia and patient outcomes after elective cardiac surgery

  2011cited by this paper
• The relationship between perioperative temperature and adverse outcomes after off-pump coronary artery bypass graft surgery.

  2010cited by this paper
• The Effects of Mild Perioperative Hypothermia on Blood Loss and Transfusion Requirement

  2008cited by this paper
• Safety of deliberate intraoperative and postoperative hypothermia for patients undergoing coronary artery surgery: a randomized trial.

  2004cited by this paper
• Temperature measurement in intensive care patients: comparison of urinary bladder, oesophageal, rectal, axillary, and inguinal methods versus pulmonary artery core method

  2003cited by this paper
• Perioperative heat balance.

  2000cited by this paper
• Incidence of atrial fibrillation after mild or moderate hypothermic cardiopulmonary bypass

  2000cited by this paper
• Association between postoperative hypothermia and adverse outcome after coronary artery bypass surgery.

  2000cited by this paper
• Effects of Mild Perioperative Hypothermia on Cellular Immune Responses

  1998cited by this paper
• Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group.

  1996cited by this paper
• The Catecholamine, Cortisol, and Hemodynamic Responses to Mild Perioperative Hypothermia: A Randomized Clinical Trial

  1995cited by this paper
• Effect of hypothermia on the coagulation cascade

  1992cited by this paper
• The relationship between axillary and core body temperature measurements.

  1990cited by this paper
• Alterations in renal function during hypothermia in man.

  1958cited by this paper
• Alterations in Renal Function During Hypothernia in Man

  1957cited by this paper

• Hybrid operating rooms and the risk of postoperative hypothermia in pregnant women with placenta previa: A retrospective cohort study

  2024cites this paper
• Low body temperature and mortality in critically ill patients with coronary heart disease: a retrospective analysis from MIMIC-IV database

  2023cites this paper
• Reliability of different body temperature measurement sites during normothermic cardiac surgery

  2022cites this paper
• The effectiveness of warming approaches in preventing perioperative hypothermia: Systematic review and meta-analysis.

  2022cites this paper