In The Light of the Guidelines: Anaphylaxis

Anafilaksi, mast hücre mediyatörlerinin sistemik dolaşıma aniden salınmasına bağlı gelişen, yaşamı tehdit edebilen multisistemik bir hastalıktır. Çoğunlukla gıdalarla, ilaçlarla ve böcek sokmalarına karşı immunoglobulin E (IgE) aracılı reaksiyonlardan kaynaklanır ancak mast hücrelerinin degranülasyonuna neden olan bir ajanda neden olabilir. Eşlik eden ağır ve kontrolsüz astım, mastositozis, kardiyovasküler hastalıklar, bazal serum triptaz yüksekliği, beta bloker veya ACE inhibitör kullanımı, egzersiz, akut enfeksiyonlar ve duygusal stres anafilaksi riskini artıran nedenlerden birkaçıdır. Anafilaksi sırasında kalp ve solunum durması dakikalar içinde gelişebileceği için tanı konulduktan hemen sonra hızla tedavi edilmelidir. Tedavide verilmesi gereken en önemli ve ilk ilaç adrenalindir. Bu derlemede anafilaksinin tanı ve tedavisi güncel literatüre göre özetlenmiştir.

• Publication year

  2021

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• Identifiers
  DOI 10.30733/std.2021.01502
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  Open on Semantic Scholar

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  Semantic Scholar

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