Gene-specific oxidative lesions in aged rat brain detected by polymerase chain reaction inhibition assay

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Free radical research

• Publication date

  2007-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/10715760601083722PMID 17364957
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells.

  2006cited by this paper
• Lipid peroxidation associated cardiolipin loss and membrane depolarization in rat brain mitochondria.

  2006cited by this paper
• Age-dependent increase of etheno-DNA-adducts in liver and brain of ROS overproducing OXYS rats.

  2005cited by this paper
• Parallel changes in gene expression in aged human and mouse cortex.

  2005cited by this paper
• Gene regulation and DNA damage in the ageing human brain

  2004cited by this paper
• Effect of DNA damage on PCR amplification efficiency with the relative threshold cycle method.

  2004cited by this paper
• Oxidative damage to DNA: formation, measurement and biochemical features.

  2003cited by this paper
• Oxidative and alkylating damage in DNA.

  2003cited by this paper
• Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration.

  2003cited by this paper
• Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment

  2003cited by this paper
• Free radical-induced damage to DNA: mechanisms and measurement.

  2002cited by this paper
• The effectiveness of increased apical enlargement in reducing intracanal bacteria.

  2002cited by this paper
• PCR-based methods for detecting DNA damage and its repair at the sub-gene and single nucleotide levels in cells

  2002cited by this paper
• PCR-based methods for detecting DNA damage and its repair at the subgene and single nucleotide levels in cells.

  2002cited by this paper
• Does oxidative damage to DNA increase with age?

  2001cited by this paper
• Lipid peroxidation associated protein damage in rat brain crude synaptosomal fraction mediated by iron and ascorbate.

  2001cited by this paper
• Levels of 8-hydroxy-2'-deoxyguanosine in cellular DNA from 12 tissues of young and old Sprague-Dawley rats.

  2001cited by this paper
• The polymerase inhibition assay: A methodology for the identification of DNA‐damaging agents

  2000cited by this paper
• DNA damage, repair, and antioxidant systems in brain regions: a correlative study.

  2000cited by this paper
• A catalytic antioxidant metalloporphyrin blocks hydrogen peroxide-induced mitochondrial DNA damage.

  2000cited by this paper
• Gene-expression profile of the ageing brain in mice

  2000cited by this paper
• NO Synthase and NO-Dependent Signal Pathways in Brain Aging and Neurodegenerative Disorders: The Role of Oxidant/Antioxidant Balance

  2000cited by this paper
• Age-related changes in reactive oxygen species production in rat brain homogenates.

  2000cited by this paper
• PCR assay of DNA damage and repair at the gene level in brain and spleen of gamma-irradiated young and old rats.

  1999cited by this paper
• Oxidative DNA damage in the aging mouse brain

  1999cited by this paper
• Antioxidants, oxidative stress, and degenerative neurological disorders.

  1999cited by this paper
• Age-related increases of 8-hydroxy-2'-deoxyguanosine and DNA-protein crosslinks in mouse organs.

  1999cited by this paper
• Structure of the rat p53 tumor suppressor gene.

  1993cited by this paper
• Iron-mediated oxidative DNA damage detected by fluorometric analysis of DNA unwinding in isolated rat liver nuclei.

  1991cited by this paper
• Bulky adducts detected by 32P-postlabeling in DNA modified by oxidative damage in vitro. Comparison with rat lung I-compounds.

  1991cited by this paper
• Iron-mediated oxidative DNA damage detected by fluorometric analysis of DNA unwinding in isolated rat liver nuclei.

  1991cited by this paper
• Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

  1990cited by this paper
• Free radicals in biology and medicine

  1985influential reference
• The nucleotide sequence of the rat cytoplasmic β–actin gene

  1983cited by this paper
• The nucleotide sequence of the rat cytoplasmic beta-actin gene.

  1983cited by this paper

• The aging brain: impact of heavy metal neurotoxicity

  2020cites this paper
• The emerging role of iron dyshomeostasis in the mitochondrial decay of aging.

  2010cites this paper