Permethrin Alters Adipogenesis in 3T3‐L1 Adipocytes and Causes Insulin Resistance in C2C12 Myotubes

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of biochemical and molecular toxicology

• Publication date

  2014-09-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1002/jbt.21580PMID 24911977
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Imidacloprid, a neonicotinoid insecticide, potentiates adipogenesis in 3T3-L1 adipocytes.

  2013cited by this paper
• Imidacloprid, a neonicotinoid insecticide, induces insulin resistance.

  2013cited by this paper
• Tipping the Balance of Autism Risk: Potential Mechanisms Linking Pesticides and Autism

  2012cited by this paper
• Environmentally relevant mixtures in cumulative assessments: an acute study of toxicokinetics and effects on motor activity in rats exposed to a mixture of pyrethroids.

  2012cited by this paper
• Regional variation in pesticide concentrations in plasma of delivering women residing in rural Indian Ocean coastal regions of South Africa.

  2012cited by this paper
• Advances in the mode of action of pyrethroids.

  2012cited by this paper
• Abnormal glucose regulation in pyrethroid pesticide factory workers.

  2011cited by this paper
• Regulation of AMP‐activated protein kinase by LKB1 and CaMKK in adipocytes

  2011cited by this paper
• CHAPTER 3:Pyrethrins and Pyrethroid Insecticides

  2011cited by this paper
• Low Dose Organochlorine Pesticides and Polychlorinated Biphenyls Predict Obesity, Dyslipidemia, and Insulin Resistance among People Free of Diabetes

  2011cited by this paper
• Organophosphorus pesticides as food chain contaminants and type 2 diabetes: a review

  2010cited by this paper
• Prenatal Organochlorine Compound Exposure, Rapid Weight Gain, and Overweight in Infancy

  2010cited by this paper
• Strong associations between low-dose organochlorine pesticides and type 2 diabetes in Korea.

  2010cited by this paper
• Monitoring health implications of pesticide exposure in factory workers in Pakistan

  2010cited by this paper
• Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance.

  2009cited by this paper
• Neonatal Organophosphorus Pesticide Exposure Alters the Developmental Trajectory of Cell-Signaling Cascades Controlling Metabolism: Differential Effects of Diazinon and Parathion

  2009cited by this paper
• Consumption of a High-Fat Diet in Adulthood Ameliorates the Effects of Neonatal Parathion Exposure on Acetylcholine Systems in Rat Brain Regions

  2009cited by this paper
• Chronic elevated calcium blocks AMPK-induced GLUT-4 expression in skeletal muscle.

  2009cited by this paper
• Chronic exposure to pyrethroid-based allethrin and prallethrin mosquito repellents alters plasma biochemical profile.

  2008cited by this paper
• Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.

  2008cited by this paper
• Characterization of 11 commercial pyrethroids on the functional attributes of rat brain synaptosomes

  2008cited by this paper
• Exposure of Neonatal Rats to Parathion Elicits Sex-Selective Reprogramming of Metabolism and Alters the Response to a High-Fat Diet in Adulthood

  2008cited by this paper
• Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003.

  2008cited by this paper
• Oxidative stress-induced insulin resistance in rat skeletal muscle: role of glycogen synthase kinase-3.

  2008cited by this paper
• Rats gain excess weight after developmental exposure to the organophosphorothionate pesticide, chlorpyrifos.

  2008cited by this paper
• AKT/PKB signaling: navigating downstream.

  2007cited by this paper
• Serum levels of insulin-like growth factor-I in relation to organochlorine pesticides exposure.

  2007cited by this paper
• WHO SPECIFICATIONS AND EVALUATIONS FOR PUBLIC HEALTH PESTICIDES

  2006cited by this paper
• Developmental Exposure of Rats to Chlorpyrifos Elicits Sex-Selective Hyperlipidemia and Hyperinsulinemia in Adulthood

  2005cited by this paper
• The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent.

  2005cited by this paper
• 2-NBDG as a fluorescent indicator for direct glucose uptake measurement.

  2005cited by this paper
• Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects.

  2005cited by this paper
• Insulin-stimulated Phosphorylation of a Rab GTPase-activating Protein Regulates GLUT4 Translocation*

  2003cited by this paper
• Mechanisms of pyrethroid neurotoxicity: implications for cumulative risk assessment.

  2002cited by this paper
• A Method to Identify Serine Kinase Substrates

  2002cited by this paper
• Mechanisms of pyrethroid neurotoxicity: implications for cumulative risk assessment.

  2002cited by this paper
• Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptors.

  2001cited by this paper
• Binding of IRS proteins to calmodulin is enhanced in insulin resistance.

  2000cited by this paper
• Nutritional and endocine modulation of intracellular calcium: Implications in obesity, insulin resistance and hypertension

  1998cited by this paper
• Whitefly (Hemiptera: Aleyrodidae) binding site for imidacloprid and related insecticides: a putative nicotinic acetylcholine receptor.

  1997cited by this paper
• Oral calcium supplementation reduces intraplatelet free calcium concentration and insulin resistance in essential hypertensive patients.

  1997cited by this paper
• Pyrethrum Flowers. Production, Chemistry, Toxicology, and Uses

  1996cited by this paper
• Agouti regulation of intracellular calcium: role in the insulin resistance of viable yellow mice.

  1995cited by this paper
• Cytosolic calcium and insulin resistance.

  1993cited by this paper
• Postprandial changes in cytosolic free calcium and glucose uptake in adipocytes in obesity and non-insulin-dependent diabetes mellitus.

  1990cited by this paper
• Toxicology of selected pesticides, drugs, and chemicals. Pyrethrin and pyrethroid insecticides.

  1990cited by this paper
• Mechanism of insulin resistance induced by sustained levels of cytosolic free calcium in rat adipocytes.

  1989cited by this paper
• Use of MTT colorimetric assay to measure cell activation.

  1986cited by this paper
• Biochemical changes in the rat cerebellum following cypermethrin administration.

  1981cited by this paper
• Structure-activity relationships of some pyrethroids in rats

  1980cited by this paper
• The action of decamethrin (a synthetic pyrethroid) on the rat

  1979cited by this paper
• Differentiation of 3T3-L1 fibroblasts to adipocytes. Effect of insulin and indomethacin on the levels of insulin receptors.

  1978cited by this paper
• Toxicity of new pyrethroid insecticide

  1974cited by this paper
• Toxicity of natural and synthetic pyrethrins to rats

  1972cited by this paper

• Permethrin Decreased Insulin Secretion and the Expression of Proteins Linked to Metabolism and Exocytosis in INS832/3 Pancreatic Beta Cells.

  2026cites this paper
• Pesticides associated with incident diabetes among licensed private pesticide applicators in the Agricultural Health Study cohort (1993-2021).

  2026cites this paper
• Review: Multigenerational effects of selected environmental contaminants in fishes: A comprehensive review.

  2026cites this paper
• Permethrin Stimulates Fat Accumulation via Regulating Gut Microbiota and Its Metabolites in Mice.

  2025cites this paper
• Sodium benzoate, a common food preservative-induced Insulin resistance and atrophy in C2C12 myotubes.

  2025cites this paper
• Association between DDT or its byproducts and T2DM: a systematic review and meta-analysis

  2025cites this paper
• Relationship between organophosphate and pyrethroid pesticides and metabolic syndrome in Korean farmers

  2024cites this paper
• Association of maternal pyrethroid pesticides exposure during the whole pregnancy with neonate lipid metabolism: A prospective birth cohort, Yunnan, China.

  2024cites this paper
• Associations of chronic exposure to a mixture of pesticides and type 2 diabetes mellitus in a Chinese elderly population.

  2024cites this paper
• Lambda-cyhalothrin-induced pancreatic toxicity in adult albino rats

  2023cites this paper
• The diabetogenic effects of pesticides: Evidence based on epidemiological and toxicological studies.

  2023cites this paper
• The Interaction of Inflammation and Exposure to Pyrethroids is Associated with Impaired Fasting Glucose and Type 2 Diabetes

  2023cites this paper
• Autophagy perturbation upon acute pyrethroid treatment impacts adipogenic commitment of mesenchymal stem cells.

  2023cites this paper
• Sex difference in the association between pyrethroids exposure and sleep problems among adolescents: NHANES 2007–2014

  2023cites this paper
• Obesity II: Establishing Causal Links Between Chemical Exposures and Obesity.

  2022cites this paper
• Membrane polarization in non-neuronal cells as a potential mechanism of metabolic disruption by depolarizing insecticides.

  2022cites this paper
• Lambda-cyhalothrin induces lipid accumulation in mouse liver is associated with AMPK inactivation.

  2022cites this paper
• Association between serum pyrethroid insecticide levels and incident type 2 diabetes risk: a nested case–control study in Dongfeng–Tongji cohort

  2022cites this paper
• Lipid Metabolic Disorder Induced by Pyrethroids in Nonalcoholic Fatty Liver Disease of Xenopus laevis.

  2022cites this paper
• Transcriptome analysis provides insight into deltamethrin-induced fat accumulation in 3T3-L1 adipocytes.

  2022cites this paper
• Permethrin inhibits tube formation and viability of endothelial cells.

  2022cites this paper
• Persistent exercise fatigue and associative learning deficits in combination with transient glucose dyshomeostasis in a mouse model of Gulf War Illness

  2021cites this paper
• THE BIOACTIVE EFFECTS OF CHICORIC ACID AS A FUNCTIONAL FOOD INGREDIENT

  2021cites this paper
• KRAS Affects Adipogenic Differentiation by Regulating Autophagy and MAPK Activation in 3T3-L1 and C2C12 Cells

  2021cites this paper
• Pyrethroids exposure induces obesity and cardiometabolic diseases in a sex-different manner.

  2021cites this paper
• Efficient and modified 2-NBDG assay to measure glucose uptake in cultured myotubes.

  2021cites this paper
• Stereoselectivity and Environmental Behaviour of Pyrethroids

  2020cites this paper
• Piceatannol attenuates fat accumulation and oxidative stress in steatosis-induced HepG2 cells

  2020cites this paper
• Pesticides-induced energy metabolic disorders.

  2020cites this paper
• β -Cypermethrin promotes the adipogenesis of 3T3-L1 cells via inducing autophagy and shaping an adipogenesis-friendly microenvironment.

  2020cites this paper
• Impact of pesticide exposure on adipose tissue development and function.

  2020cites this paper
• Obesity Worsens Gulf War Illness Symptom Persistence Pathology by Linking Altered Gut Microbiome Species to Long-Term Gastrointestinal, Hepatic, and Neuronal Inflammation in a Mouse Model

  2020cites this paper
• Multi- and transgenerational effects following early-life exposure of zebrafish to permethrin and coumarin 47: Impact on growth, fertility, behavior and lipid metabolism.

  2020cites this paper
• The relationship of urinary 3-phenoxybenzoic acid concentrations in utero and during childhood with adiposity in 4-year-old children.

  2019cites this paper
• Environmental pyrethroid exposure and diabetes in U.S. adults.

  2019cites this paper
• Chlorantraniliprole induces adipogenesis in 3T3-L1 adipocytes via the AMPKα pathway but not the ER stress pathway.

  2019cites this paper
• Effects of Ivermectin and Perfluorobutanesulfonic Acid (PFBS) on Lipid Metabolism

  2019cites this paper
• Deltamethrin promotes adipogenesis via AMPKα and ER stress-mediated pathway in 3T3- L1 adipocytes and Caenorhabditis elegans.

  2019cites this paper
• Ivermectin decreases triglyceride accumulation by inhibiting adipogenesis of 3T3-L1 preadipocytes.

  2019cites this paper
• Chicoric acid promotes glucose uptake and Akt phosphorylation via AMP-activated protein kinase α-dependent pathway

  2019cites this paper
• Pyrethroid Insecticides: An Update

  2019cites this paper
• Identification of metabolic pathways related to the bisphenol A‐induced adipogenesis in differentiated murine adipocytes by using RNA‐sequencing

  2019cites this paper
• Permethrin and ivermectin modulate lipid metabolism in steatosis-induced HepG2 hepatocyte.

  2019cites this paper
• Flubendiamide Enhances Adipogenesis and Inhibits AMPKα in 3T3-L1 Adipocytes

  2018cites this paper
• Effects of pyrethroid pesticide cis-bifenthrin on lipogenesis in hepatic cell line.

  2018cites this paper
• Pyrethroid Insecticides as the Mitochondrial Dysfunction Inducers

  2018cites this paper
• Permethrin, a pyrethroid insecticide, regulates ERK1/2 activation through membrane depolarization-mediated pathway in HepG2 hepatocytes.

  2018cites this paper
• Diazinon exposure activated transcriptional factors CCAAT-enhancer-binding proteins α (C/EBPα) and peroxisome proliferator-activated receptor γ (PPARγ) and induced adipogenesis in 3T3-L1 preadipocytes.

  2018cites this paper
• Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice.

  2018cites this paper
• Permethrin potentiates adipogenesis via intracellular calcium and endoplasmic reticulum stress-mediated mechanisms in 3T3-L1 adipocytes.

  2017cites this paper
• Pear pomace ethanol extract improves insulin resistance through enhancement of insulin signaling pathway without lipid accumulation

  2017cites this paper
• Permethrin alters glucose metabolism in conjunction with high fat diet by potentiating insulin resistance and decreases voluntary activities in female C57BL/6J mice.

  2017influential citation
• Pyrethroid pesticides in the autophagy/apoptosis balance: Role in adipocyte lipidogenesis.

  2017cites this paper
• Deltamethrin increases the fat accumulation in 3T3-L1 adipocytes and Caenorhabditis elegans.

  2017influential citation
• EFFECTS OF PERMETHRIN, A PYRETHROID INSECTICIDE, ON GLUCOSE AND LIPID METABOLISM

  2017cites this paper
• IMIDACLOPRID, A NEONICOTINOID INSECTICIDE, IMPAIRS LIPID AND GLUCOSE METABOLISM

  2017influential citation
• Permethrin decreased insulin-stimulated AKT phosphorylation dependent on extracellular signal-regulated kinase-1 (ERK), but not AMP-activated protein kinase α (AMPKα), in C2C12 myotubes.

  2017cites this paper
• Imidacloprid Promotes High Fat Diet-Induced Adiposity in Female C57BL/6J Mice and Enhances Adipogenesis in 3T3-L1 Adipocytes via the AMPKα-Mediated Pathway

  2017cites this paper
• Activity 6-2-2016 4 , 4 ’-Dichlorodiphenyltrichloroethane ( DDT ) and 4 , 4 ’-dichlorodiphenyldichloroethylene ( DDE ) promote adipogenesis in 3 TL 1 adipocyte cell culture

  2017cites this paper
• Potential contribution of insecticide exposure and development of obesity and type 2 diabetes.

  2017cites this paper
• 4,4'-Dichlorodiphenyltrichloroethane (DDT) and 4,4'-dichlorodiphenyldichloroethylene (DDE) promote adipogenesis in 3T3-L1 adipocyte cell culture.

  2016cites this paper
• Imidacloprid Promotes High Fat Diet-Induced Adiposity and Insulin Resistance in Male C57BL/6J Mice

  2016cites this paper
• Prenatal pesticide exposure and PON1 genotype associated with adolescent body fat distribution evaluated by dual X‐ray absorptiometry (DXA)

  2016cites this paper
• Metal and Microelement Biomarkers of Neurodegeneration in Early Life Permethrin-Treated Rats

  2016cites this paper
• Fipronil promotes adipogenesis via AMPKα-mediated pathway in 3T3-L1 adipocytes.

  2016cites this paper
• Environmental chemical risk factors for Type 2 diabetes: an update

  2015cites this paper