Rabdomiossarcoma botrióide na vesícula urinária de um American Pitbull Terrier

O rabdomiossarcoma botrioide e uma variante do rabdomiossarcoma embrionario e tem origem nas celulas musculares estriadas, ou precursores destas celulas, por isso podem se iniciar em partes do corpo com ausencia de musculo estriado, como o trato urogenital. Geralmente, os caes acometidos sao jovens ate dois anos e as massas neoplasicas tem aspecto de cacho de uva. O objetivo do presente relato foi descrever um caso de rabdomiossarcoma botrioide em um cao, American Pittbull Terrier, de 16 meses que apresentou uma massa no interior da vesicula urinaria, posteriormente diagnosticada atraves de exame histopatologico e imunoistoquimico. A massa era multilobulada, firme, rosea a vermelha com areas multifocais de necrose e estava aderida na mucosa da regiao mais cranial da vesicula urinaria emitindo ramificacoes disseminadas em direcao ao trigono vesical. Microscopicamente, a neoplasia e constituida por duas populacoes celulares entremeadas a uma matriz mixoide, uma composta por celulas pequenas e redondas, com citoplasma escasso e nucleo basofilico hipercorado e a outra por celulas alongadas, com citoplasma eosinofilico e nucleo paracentral, ambas as populacoes celulares possuiam pleomorfismo moderado e 2 figuras de mitose por campo (400 x). Densidade celular aumentada foi observada abaixo do epitelio vesical. A combinacao de exames complementares foi conclusiva para o diagnostico da neoplasia.

• Publication year

  2021

• Venue

  Research, Society and Development

• Publication date

  2021-05-12

• Fields of study

  Not labeled

• Identifiers
  DOI 10.33448/RSD-V10I5.14888
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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