Tamoxifen Modulation of Etoposide Cytotoxicity Involves Inhibition of Protein Kinase C Activity and Insulin-Like Growth Factor II Expression in Brain Tumor Cells

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Neuro-Oncology

• Publication date

  2004-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1023/B:NEON.0000021738.77612.1bPMID 15072444
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2006cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
• Surgery, Tamoxifen, Carboplatin, and Radiotherapy in the Treatment of Newly Diagnosed Glioblastoma Patients

  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
• Tamoxifen alters levels of serum insulin-like growth factors and binding proteins in postmenopausal breast cancer patients: A prospective paired cohort study

  1998cited by this paper
• Tamoxifen modulation of carboplatin cytotoxicity in a human U-138 glioma cell line.

  1998cited by this paper
• Phorbol ester-induced P-glycoprotein phosphorylation and functionality in the HTB-123 human breast cancer cell line.

  1998cited by this paper
• Antagonist effect of insulin-like growth factor I on protein kinase inhibitor-mediated apoptosis in human glioblastoma cells in association with bcl-2 and bcl-xL.

  1998influential reference
• Tamoxifen in the treatment of breast cancer.

  1998cited by this paper
• Tamoxifen and carboplatin combinational treatment of high-grade gliomas Results of a clinical trial on newly diagnosed patients

  1998cited by this paper
• Tumors of the central nervous system.

  1998cited by this paper
• A phase I study of high-dose tamoxifen for the treatment of refractory malignant gliomas of childhood.

  1997cited by this paper
• Phase II study of daily oral etoposide in children with recurrent brain tumors and other solid tumors.

  1997cited by this paper
• Recurrent supratentorial malignant gliomas in children. Long-term salvage therapy with oral etoposide.

  1997cited by this paper
• CGP 41251 and tamoxifen selectively inhibit mitogen-activated protein kinase activation and c-Fos phosphoprotein induction by substance P in human astrocytoma cells.

  1997cited by this paper
• Tamoxifen interferes with the insulin-like growth factor I receptor (IGF-IR) signaling pathway in breast cancer cells.

  1997cited by this paper
• Tamoxifen for the treatment of malignancies other than breast and endometrial carcinoma.

  1997cited by this paper
• Treatment of recurrent malignant gliomas with chronic oral high-dose tamoxifen.

  1996cited by this paper
• Tamoxifen Modulates Protein Kinase C via Oxidative Stress in Estrogen Receptor-negative Breast Cancer Cells*

  1996cited by this paper
• Phase II study of prolonged oral therapy with etoposide (VP16) for patients with recurrent malignant glioma

  1996cited by this paper
• Insulin-like growth factors in breast cancer.

  1996cited by this paper
• Inhibitory effects of tamoxifen and tumor necrosis factor alpha on human glioblastoma cells.

  1995cited by this paper
• Interaction of tamoxifen with the multidrug resistance P-glycoprotein.

  1995cited by this paper
• Insulin-like growth factors and breast cancer.

  1995cited by this paper
• The efficacy of tamoxifen as an antiproliferative agent in vitro for benign and malignant pediatric glial tumors.

  1995cited by this paper
• Inhibitory effects of tamoxifen and tumor necrosis factor α on human glioblastoma cells

  1995cited by this paper
• Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen.

  1993cited by this paper
• Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. A comparison between staurosporine and tamoxifen.

  1993cited by this paper
• Effect of endocrine therapy on growth of T61 human breast cancer xenografts is directly correlated to a specific down-regulation of insulin-like growth factor II (IGF-II).

  1993cited by this paper
• Thaliblastine, a plant alkaloid, circumvents multidrug resistance by direct binding to P-glycoprotein.

  1993cited by this paper
• Tamoxifen modulation of cisplatin cytotoxicity in human malignancies

  1993cited by this paper
• High Dose Tamoxifen in the Treatment of Recurrent High Grade Glioma: A Report of Clinical Stabilization and Tumour Regression

  1993cited by this paper
• Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase C.

  1992cited by this paper
• High-dose oral tamoxifen, a potential multidrug-resistance-reversal agent: phase I trial in combination with vinblastine.

  1992cited by this paper
• Enhancement of radiosensitivity by tamoxifen in C6 glioma cells.

  1992cited by this paper
• Suppression of mouse mammary tumorigenesis by long-term tamoxifen therapy.

  1991cited by this paper
• Sex steroid receptors in intracranial tumors

  1990cited by this paper
• The impact of childhood cancer on the United States and the world

  1990cited by this paper
• Effect of tamoxifen on DNA synthesis and proliferation of human malignant glioma lines in vitro.

  1990influential reference
• Tamoxifen in the treatment of breast cancer.

  1988cited by this paper
• Effects of acute high dose and chronic low dose estrogen on plasma somatomedin-C and growth in patients with Turner's syndrome.

  1988cited by this paper
• Calcium channel antagonist properties of the antineoplastic antiestrogen tamoxifen in the PC12 neurosecretory cell line.

  1987cited by this paper
• Cancer incidence, survival, and mortality for children younger than age 15 years

  1986cited by this paper
• Inhibition of protein kinase C by tamoxifen.

  1985cited by this paper
• Analysis of combined drug effects: a new look at a very old problem

  1983influential reference
• Tumors of the central nervous system

  1972cited by this paper
• The United States and the world

  1965cited by this paper

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  2023cites this paper
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  2021cites this paper
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  2020cites this paper
• The effect of tamoxifen on IGF signaling pathway in mouse ovary

  2019cites this paper
• Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity

  2017cites this paper
• Delineating the molecular mechanisms of tamoxifen's oncolytic actions in estrogen receptor-negative cancers.

  2016cites this paper
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  2015cites this paper
• Novel Aspects Concerning the Functional Cross-Talk between the Insulin/IGF-I System and Estrogen Signaling in Cancer Cells

  2015cites this paper
• Review on the Role of Estrogen Receptors in Breast Cancer

  2015cites this paper
• Tamoxifen Prevents Apoptosis and Follicle Loss from Cyclophosphamide in Cultured Rat Ovaries1

  2015cites this paper
• Radiosensitization of human glioma cells by tamoxifen is associated with the inhibition of PKC-ι activity in vitro.

  2015cites this paper
• Improved Neuroprotective Effects by Combining Bacopa monnieri and Rosmarinus officinalis Supercritical CO2 Extracts

  2014cites this paper
• Tamoxifen inhibits migration of estrogen receptor‐negative hepatocellular carcinoma cells by blocking the swelling‐activated chloride current

  2013cites this paper
• Journal of Complementary and Integrative Medicine Potentiation of Etoposide and Temozolomide Cytotoxicity by Curcumin and Turmeric Force TM in Brain Tumor Cell Lines

  2012cites this paper
• Targets for therapy in ependymoma

  2011cites this paper
• A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat

  2011cites this paper
• The role of estrogen and estrogen receptors in chemoresistance.

  2011cites this paper
• Roles and Mechanisms of Estrogen and Estrogen Receptors in Breast Cancer Resistant to Chemotherapy

  2011cites this paper
• Potentiation of gemcitabine by Turmeric Force in pancreatic cancer cell lines.

  2010cites this paper
• Isolation and characterization of an anticancer catechol compound from Semecarpus anacardium.

  2009cites this paper
• Salvage chemotherapy for metastatic and recurrent ependymoma of childhood

  2009cites this paper
• Targeting malignant glioma survival signalling to improve clinical outcomes.

  2007cites this paper
• Recurrent ependymoma treated with high‐dose tamoxifen in a peripubertal female: Impact on tumor and the pituitary–ovarian axis

  2007cites this paper
• Antiestrogenic effect of 20S‐protopanaxadiol and its synergy with tamoxifen on breast cancer cells

  2007cites this paper
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  2007cites this paper
• New treatment strategies for malignant gliomas

  2006cites this paper
• PKC eta as a therapeutic target in glioblastoma multiforme.

  2005cites this paper
• Human central nervous system tissue culture: a historical review and examination of recent advances.

  2005cites this paper
• PKCη as a therapeutic target in glioblastoma multiforme

  2005cites this paper