The Discordance Between the Renal Histopathology and Clinical Presentation of Diabetic Nephropathy Calls for Novel Approaches for the Prediction and Monitoring of Kidney Failure in Diabetes

A dvances in our understanding of the pathogenesis of diabetic nephropathy are severely hampered by our limited knowledge as to how kidney histopathological changes mirror clinically available markers, such as urinary albumin excretion and estimated glomerular filtration rate and vice versa. A significant obstacle in this regard has been the low number of renal biopsy specimens obtained in clinical practice as part of diagnosing and monitoring diabetic nephropathy. This is particularly relevant over the last 20 years when most clinicians have considered the limited gain and potential risk of performing kidney biopsies. Thus, in clinical

• Publication year

  2021

• Venue

  Kidney International Reports

• Publication date

  2021-08-08

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.ekir.2021.07.029PMID 34514188PMCID 8419110
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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