Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Food and Chemical Toxicology

• Publication date

  2001-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0278-6915(00)00119-8PMID 11267705
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation

  1998cited by this paper
• Cytochromes P450 and species differences in xenobiotic metabolism and activation of carcinogen.

  1998cited by this paper
• Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6‐hydroxylation

  1998cited by this paper
• Human lymphocyte cytochrome P450 2E1, a putative marker for alcohol-mediated changes in hepatic chlorzoxazone activity.

  1997cited by this paper
• Cytochrome P-4502E1: its physiological and pathological role.

  1997cited by this paper
• Drugs, diet and disease

  1996cited by this paper
• Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype.

  1996cited by this paper
• Cytochromes P450 Metabolic and Toxicological Aspects

  1996cited by this paper
• Role of cytochrome P4502E1‐dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol

  1996cited by this paper
• Cytochrome P450 2: peroxidative reactions of diversozymes.

  1996cited by this paper
• P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

  1996cited by this paper
• Extrahepatic expression of P450 proteins in insulin-dependent diabetes mellitus.

  1995cited by this paper
• Use of lymphocytes for assessing ethanol-mediated alterations in the expression of hepatic cytochrome P4502E1.

  1995cited by this paper
• Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species.

  1994cited by this paper
• HEPATIC CYTOCHROME-P450 PROFILE IN BB RATS WITH SPONTANEOUS INSULIN-DEPENDENT DIABETES-MELLITUS

  1994cited by this paper
• Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less.

  1994cited by this paper
• Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins.

  1994cited by this paper
• Comparison of levels of cytochromes P-450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples.

  1993cited by this paper
• Ethanol-inducible cytochrome P4502E1: genetic polymorphism, regulation, and possible role in the etiology of alcohol-induced liver disease.

  1993cited by this paper
• Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high.

  1993cited by this paper
• Life-span and cancer: the induction time of tumors in diverse animal species treated with nitrosodiethylamine.

  1993cited by this paper
• Pretranslational activation of cytochrome P450IIE during ketosis induced by a high fat diet.

  1992cited by this paper
• Induction of rat hepatic mixed-function oxidases by acetone and other physiological ketones: their role in diabetes-induced changes in cytochrome P450 proteins.

  1992cited by this paper
• Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects.

  1991cited by this paper
• Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1.

  1991cited by this paper
• Role of ethanol-inducible cytochrome P450 (P450IIE1) in catalysing the free radical activation of aliphatic alcohols.

  1991cited by this paper
• Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes.

  1991cited by this paper
• Hyperketonaemia markedly modulates the metabolic activation of chemical carcinogens.

  1990cited by this paper
• Cytochrome P450IIE1 is elevated in lymphocytes from poorly controlled insulin-dependent diabetics.

  1990cited by this paper
• Cytochrome P450IIE1: roles in nitrosamine metabolism and mechanisms of regulation.

  1990cited by this paper
• Multiple mechanisms in the regulation of ethanol‐inducible cytochrome P450IIE1

  1990cited by this paper
• Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes.

  1990cited by this paper
• Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

  1990cited by this paper
• Cytochrome P-450 and oxygen toxicity. Oxygen-dependent induction of ethanol-inducible cytochrome P-450 (IIE1) in rat liver and lung.

  1989cited by this paper
• Induction of rat hepatic N-nitrosodimethylamine demethylase by acetone is due to protein stabilization.

  1989cited by this paper
• Role of ketone bodies in the diabetes-induced changes in hepatic mixed-function oxidase activities.

  1988cited by this paper
• Pyridine induction of cytochrome P-450 in the rat: role of P-450j (alcohol-inducible form) in pyridine N-oxidation.

  1988cited by this paper
• Hepatic cytochrome P-450j induction in the spontaneously diabetic BB rat.

  1988cited by this paper
• The predictivity of animal bioassays and short-term genotoxicity tests for carcinogenicity and non-carcinogenicity to humans.

  1987cited by this paper
• Stabilization of cytochrome P450j messenger ribonucleic acid in the diabetic rat.

  1987cited by this paper
• Hydroxyl-radical production and ethanol oxidation by liver microsomes isolated from ethanol-treated rats.

  1986cited by this paper
• Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme.

  1986cited by this paper
• Ethanol oxidation and toxicity: role of alcohol P-450 oxygenase.

  1986cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Mechanism of induction of hepatic microsomal drug metabolizing enzymes by a series of barbiturates

  1975cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• Isolation of mononuclear cells and granulocytes from human blood.

  1968cited by this paper

• Acrylamide-derived DNA adducts in human peripheral blood mononuclear cell DNA: Correlation with body mass.

  2021cites this paper
• Utility of Quantitative Proteomics for Enhancing the Predictive Ability of Physiologically Based Pharmacokinetic Models Across Disease States

  2020cites this paper
• Compartmentalized effects of aging on group 2 innate lymphoid cell development and function

  2019cites this paper
• Alterations of drug-metabolizing enzymes and transporters under diabetic conditions: what is the potential clinical significance?

  2018cites this paper
• Effets du diabète de type 2 sur l’expression et l’activité des cytochromes P450 hépatiques et extra-hépatiques chez la souris C57BL/6 sous une diète riche en gras

  2017cites this paper
• Targeted CYP2E1 quantification and its correlation to currently acceptable clinical biochemical indices

  2016cites this paper
• Effect of Diabetes Mellitus on the Metabolism of Drugs and Toxins

  2015cites this paper
• Effects of type 1 and type 2 diabetes on the pharmacokinetics of tramadol enantiomers in patients with neuropathic pain phenotyped as cytochrome P450 2D6 extensive metabolizers

  2014cites this paper
• Effect of Diabetes Mellitus on Pharmacokinetic and Pharmacodynamic Properties of Drugs

  2012cites this paper
• The use of degenerate oligonucleotide primed polymerase chain reaction (DOP-PCR) technique to detect and isolate cytochrome P450 2E1 and 2A genes

  2012cites this paper
• Effect of Diabetes Mellitus on Pharmacokinetic and Pharmacodynamic Properties of Drugs

  2012cites this paper
• Drug metabolizing enzymes and transporters mRNA in peripheral blood mononuclear cells of healthy subjects: biological variations and importance of pre-analytical steps.

  2009cites this paper
• Lymphocyte cytochrome P450 expression: inducibility studies in male Wistar rats

  2008cites this paper
• Transcription Factor and Drug-Metabolizing Enzyme Gene Expression in Lymphocytes from Healthy Human Subjects

  2008cites this paper
• The role of oxidative stress in diabetic complications

  2007cites this paper
• Antidiabetic Properties of 2,5-Dihydroxy-4,3′-Di(β-D-Glucopyranosyloxy)-trans-Stilbene from Mulberry (Morus bombycis Koidzumi) Root in Streptozotocin-Induced Diabetic Rats

  2007cites this paper
• Mechanisms and Outcomes of Drug- and Toxicant-Induced Liver Toxicity in Diabetes

  2007cites this paper
• Pharmacodynamics, Chiral Pharmacokinetics, and Pharmacokinetic‐Pharmacodynamic Modeling of Fenoprofen in Patients With Diabetes Mellitus

  2006cites this paper
• Oxidative and Glycooxidative Stress in Diabetic Nephropathy

  2006cites this paper
• Methyl-parathion and organophosphorous pesticide metabolites modify the activation status and interleukin-2 secretion of human peripheral blood mononuclear cells.

  2005cites this paper
• CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes.

  2005cites this paper
• Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals.

  2005cites this paper
• Effect of insulin-mimetic vanadyl sulfate on cytochrome P450 2E1-dependent p-nitrophenol hydroxylation in the liver microsomes of streptozotocin-induced type 1 diabetic rats.

  2005cites this paper
• Bioequivalence revisited: Influence of age and sex on CYP enzymes

  2004cites this paper
• Novel inhibitors of advanced glycation endproducts.

  2003cites this paper
• Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes

  2003cites this paper
• The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine

  2003cites this paper
• Identification of a 16-Nucleotide Sequence That Mediates Post-transcriptional Regulation of Rat CYP2E1 by Insulin*

  2002cites this paper
• Neurovascular disease, antioxidants and glycation in diabetes

  2002cites this paper
• Diabetes and elimination of antipyrine in man: an analysis of 298 patients classified by type of diabetes, age, sex, duration of disease and liver involvement.

  2002cites this paper
• Dynamic and kinetic disposition of nisoldipine enantiomers in hypertensive patients presenting with type-2 diabetes mellitus

  2002cites this paper
• Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population

  2002cites this paper
• Novel inhibitors of advanced glycation endproducts.

  1999cites this paper